Volume-6 ~ Issue-4

Abstract: The compositions of the areal parts of essential oils of Artemisia abyssinica, A. absinthium (Ariti), and A. annua have been studied. The oils were examined by GC, GC/MS, 1HNMR, and 13CNMR techniques.The total constituents of the oils 59%, 56%, and 44% have been identified from A. abyssinica, A. absinthium(Ariti), and A. annua respectively. The major components were yomogi alcohol and artemisia alcohol acetate for A. abyssinica; camphor,davanone and chamazulene for A. absinthium and camphor for A. annua. Four compounds were isolated from A. abyssinica and A. absinthium and their structure were elucidated based on spectroscopic techniques.

Key words: Artemisia, A. absinthium ( Ariti),anisaldehyde reagent ,chamazulene,essential oils, monoterpenes.

[1]. http://www.essential-oil.org/essential_oilcomponents.asp
[2]. http://www.ics.trieste.it/MAPs/EssentialOils_Compound.aspx?id=4
[3]. M.R. Verdian-rizi, E. Sadat-Ebrahimi, A. Hadjiakhoondi, M.R. Fazeli and P. Hamedani, Chemical Composition and Antimicrobial Activity of Artemisia annua L. Essential Oil from Iran, Journal of Medicinal Plants, 7 (4), 2008, 123-127
[4]. G. Brown, G. Liang and L. SY, Terpenoids from the Seeds of Artemisia annua, Phytochemistry, 64, 2003, 303-323
[5]. S. Khangholil, and A. Rezaeinodehi, Effect of Drying Temperature on Essential Oil Content and Composition of Sweet Wormwood (Artemisia annua) Growing Wild in Iran, Pak. J. Biol. Sci., 11 (6), 2008, 934-937
[6]. B. Abegaz and W. Herz, A Non-Monoterpene from Artemisia schimperi, Phytochemistry, 30, 1991, 1011-1012
[7]. B. Abegaz and G. Yohannes, Constituents of the Essential Oil of Artemisia rehan, Phytochemistry, 21 (7), 1982, 1791-1793
[8]. C. Dale and M. John, Model Studies of Biosynthesis of Non-Head-to-Tail Terpenes. Stereochemistry of Ionization for N-Methyl-4-[(1S,1'R,3'R)-[1-2H]chrysanthe- myloxy] -pyridinium Iodide, J. Am. Chem. Soc., 99, 1977, 3824-3829
[9]. C. Dale and M. John, Model Studies of Biosynthesis of Non-Head-to-Tail Terpenes, stereochemistry of the head-to-head Rearrangement, J. Am. Chem. Soc., 99, 1977, 3830-3837
[10]. J. Leland, B. Peter, L. Sara, A. James and L. Herry, Natural Products from Plants 2nd edition, 2006, 10- 11

Abstract: First of all I give my love to all the students who reside in 'Chemistry Phobia zone'. In this short article I shall try to share my simple thinking that I achieved during my last 16 years of journey in the route of Chemical Education. Before starting my journey it was a big encounter for me to change the conventional methods and makes chemistry easier and interesting to such student who belongs to Chemistry Paranoia Zone. I believe that students are just like flowers and it is our duty to nourish them properly as a gardener. In my infinitely small area of knowledge, I just try to innovate fourteen (14) teaching methodologies by including thirty four (34) completely new formulae in the chemistry world which were followed by different eminent writers in their books since last 90-95 years namely Sir G.Wilkinson, Prof. F. Albert Cotton, Prof. I.L.Finar, Prof. R.T. Morrison, Prof. R.N. Boyd, Prof. Solomons and Prof. Fryhle, Prof. J.G. Smith etc.

Key words: Hybridization, Bond-order, Acid radical, Bond-Distances, Spin Multiplicity, Aromatic and Anti aromatic compound, Magnetic Moment, Open chain olefinic system, cyclic olefinic system, π and σ-bond, double and single bond, number of carbon and hydrogen atoms.

[1]. Lee.J.D.(2009 5th ed.), Concise Inorg. Chem, ; Wiley India and Oxford, 944 and 109-112.
[2]. Douglas.B.(2007 3rd ed.), Mcdaniel. D. and Alexander.J., Concepts and Models of Inorg. Chem.,; Wiley India, 157 and 38.
[3]. Cotton.F.A.,Wilkinson.G.and Gaus.P.L.(2007 3rd ed.),Basic Inorg.Chem.,;Wiley India, 107, 523 & 111.
[4]. Mahan. B.M. and Meyers.R.J. (1998 4th ed.),International Student Edition University Chemistry,599-603,.
[5]. Dutta R.L., Inorganic Chem.(2009 6th ed.P1), 146-147.
[6]. Finar I.L, Organic Chemistry, Vol-1, (2004 6th ed.), 1, 532, 577-580, Pearson.
[7]. Morrison R.T. and Boyd R.N., 7th ed., Organic Chemistry, 208, Pearson.
[8]. Solomons T.W.Graham and Fryhle C.B. (2009 & 2012 10th ed.), Organic Chemistry,150, 632- 639, Wiley India.
[9]. Madan R.L.,Chem.(2011 1st ed.), p88.
[10]. Smith J.G. (2008 2nd ed.), Organic chemistry, 616-619.

Abstract: Three new ternary copper(II) complexes formulated as [Cu(HIda)(bipy)] 1; [Cu(HIda)(phen)] 2; [Cu(HIda)(dmp)] 3; where HIda =N-(2-hydroxyethyl)-2- iminodiacetic acid ; bipy = 2, 2'- bipyridine; phen = 1,10- phenanthroline; dmp = 2,9-dimethyl 1,10-phenanthroline, have been synthesized and characterized by partial elemental analysis, FAB-mass (m/z), EPR, UV-visible and CV measurements. The magnetic and spectroscopic data of all these complexes 1-3 indicate distorted octahedral geometry. The EPR spectra of these complexes in frozen DMSO solutions showed a single at g ca. 2. The trend in g-value (g||>g>2.0023) suggests that the unpaired electron on copper (II) has dx2–y2 character. The SOD activities of the complexes have been investigated. Antibacterial and antifungal activity of these complexes were also measured and discussed.

Key words: Copper (II) complexes; EPR spectra; SOD activity, antibacterial and antifungal activity.

[1]. H. Sigel (Ed.), Metal ions in Biological System, vol.12, Marcel Dekker, New York (1981).
[2]. H. Sigel (Ed.), Metal ions in Biological Systems, Vol.13, Marcel Dekker, New York (1981).
[3]. T. Miura, A. Hori-i, H. Mototani and H. Takeuchi, Biochemistry, 38, 11560 (1999).
[4]. J. D. Ranford and P.J. Sadler, J. Chem. Soc., Dalton Trans., 3393 (1993).
[5]. G. Majella, S. Vivienne, M. Malachy, D. Michael and M. Vickie, Polyhedron, 18, 2931 (1999).
[6]. D. K. Saha, U. Sandbhor, K. Shirisha, S. Paddye, D. Deobagkar, C.E. Ansond and A. K. Powell, Bioorg. Med. Chem. Lett., 14, 3027 (2004).
[7]. M. A. Zoroddu, S. Zanetti, R. Pogni and R. Basosi, J. Inorg. Biochem., 63, 291 (1996).
[8]. R. N. Patel, N.singh, K. K. Shukla, V. L. N. Gundla and U. K. Chauhan, Spectrochim. Acta. A63, 21 (2006).
[9]. L. W. Oberley and G.R. Buettner Cancer Res, 39 (1979) 1141
[10]. J. M. Mc Cord, Biol. Med., 2, 307 (1986).

Abstract: Five new mixed-ligand nickel (II) complexes; viz; [Ni (BHM)(PMDT)]1; [Ni(BHM)(dien)] 2; [Ni(BHM)(L1)]3; [Ni(BHM)(L2)] 4, [Ni(BHM)(L3)] 5; where H2BHM= N'-(1E)-(5-bromo-2-hydroxyphenyl) methylidene] benzoylhydrazide, PMDT= N,N,N',N,"N"-Pentamethyldiethylenetriamine; dien= diethylenetriamine; L1 = N,N- dimethyl-N' (Pyrid-2-yl-methyl) ethylenediamine; L2= N-methyl-N'-(pyrid-2-ylmethyl)ethylenediamine; L3 = N,N-dimethyl-N'-(6-methyl)pyrid-2-ylmethyl) ethylenediamine, have been synthesized and characterized by using elemental analyses, FAB (fast atomic bombardment), magnetic measurements, electronic absorption , conductivity measurements, cyclic voltammetry (CV) and IR- spectroscopy . All the complexes yielded an irreversible couple that can be assigned to a NiII→ NiI redox process. Infrared spectra, ligand field spectra and magnetic susceptibility measurements agree with the observed octahedral environment. H2BHM is a diprotic tridentate Schiff base ligand (ONO donor atom) whereas L1-L3 possessing N3 coordination sites. The SOD activities have been measured using alkaline DMSO as a source of superoxide radical (O2–) and nitro blue tetrazolium (NBT) as O2– scavenger.

Key words: Nickel (II) complexes; Schiff bases; CV; UV-Visible; SOD activity.

[1]. M.G.B. Drew, S.M. Nelson and J. ReedijkInorg. Chem. Acta, 64, 1189 (1982).
[2]. P.K. Caughlin and S.J. Lippard, Inorg. Chem., 23, 1446 (1984).
[3]. C.A. Salata, M.T. Youinon and C.J. Burrows, J. Am. CHem. Soc. 111, 9278 (1989).
[4]. M.E. Stroupe, M. DiDonato, J.A. Tainer, In: A. Messer Schmidt, R. Huber, R. Poulos and K. Weighardt (eds.). Hand Book of Metalloproteins, Wiley, England, (2001).
[5]. H.D. Younet al. Arch. Biochem. Biopsy's., 334, 341, (1996).
[6]. H.D. Youn, E.J. Kin, J.H. Roe, Y.C. Hah and S.O. Kang, J. Biochem., 318, 889 (1996).
[7]. J.M. Mc Cord, Superoxide Dismutase, 349, 331, (2002).
[8]. R. N. Patel, N. Singh, K.K. Shukla, V.L. N. Gundla and U.K. Chauhan, Spectrochim. Acta, A63, 21 (2006).
[9]. L. W. Oberley and G. R. Buettner , Cancer Res, 39, 1141(1979)
[10]. J.R.G. Sorenson, Chem. Ber., 21, 169 (1989).

Abstract: Complexes of some lanthanide picrates (Ln3+ = Pr3+, Nd3+ and Dy3+) with benzo-18-crown-6 and 221-cryptand were synthesized and characterized by elemental analysis, FTIR, and UV-Visible. Spectrophotometric methods, thermal analysis (TGA & DTG), melting point, magnetic susceptibility and molar conductance. Also an in-vitro study on gram positive (Staphylococcus aureus) and gram negative bacteria (Escherichia coli, Salmonella and pseudomonas aeruginosa) was performed and the results were compared to those of the broad spectrum antibiotic Chloramphinicol. The benzo-18-crown-6 complexes have the general formula of [Ln.L.(Pic)2]Pic.nH2O , where; (Ln3+ = Pr3+, Nd3+, and Dy3+) , (L = Benzo-18-crown-6) , (Pic = Picrate anion) , (n = 1-2). In these complexes two picrate anions are coordinated to the metal ion through the phenolic oxygen and oxygen of the ortho nitro group, thus, the metal ions in these complexes have a coordination number of (10). The complexes of 221-cryptand have the general formula of [Ln.L.(Pic)]Pic2.nH2O where; (Ln3+ = Pr3+, Nd3+, and Dy3+), (L = 221-cryptand), (Pic = Picrate anion), (n = 1,2 or 7). In these complexes one picrate anion is coordinated to the metal ion, also through the phenolic oxygen and the oxygen from the ortho nitro group, thus the metal ions in the cryptand complexes have a coordination number of (9).

Key words: crown ethers, lanthanides, picrates, cryptand.

[1] Sergey, P. B., and Anna, V. G. , Lanthanide Paramagnetic Probes for NMR Spectroscopic Studies of Fast Molecular Conformational Dynamics and Temperature Control.18-Crown-6 Intramolecular Reorientation in Complexes of Cerium(III) Chelates, Макрогетероциклы / Macroheterocycles, 5(2), 2012, pp. 178 – 181.
[2] Sudhindra, N. M., Minaz, A. G., Indira, D. M., and Ram, S. Biological and Clinical Aspects of Lanthanide Coordination Compounds, Bioiorganic Chemistry and Applications, vol. 2, 2004, pp. 3 – 4.
[3] Robin, D. R., Andrew, N. R., and Mathew, M. B., f – Element/Crown Ether Complexes. Preparation and Structural Characterization of Lanthanide Chloride Complexes of 12-crown-4. Inorg. Chem., 27, 1988, pp. 3826 – 3835.
[4] Robin, D. R., and Lynn, K. K. , f – Element/Crown Ether Complexes. Synthesis and crystal and Molecular Structures of [MCl(OH2)2(18-crown-6)]Cl2.2H2O (M = Sm, Gd, Tb). Inorg. Chem., 26, 1987, pp. 1498 – 1502.
[5] King, R. B., and Paul, R. H., Lanthanide Nitrate Complexes of Some Macrocyclic Polyethers. Journal of the American Chemical Society, 1974, 96:10.
[6] Lawrence, L. David, J. B., and Gordon, W. B., Lanthanide and Yttrium Complexes of Deprotonated 4,13-Diaza-18-crown-6 (DAC): Synthesis and Structural Characterization of Y [DAC][N(SiMe3)2] and the Novel Trinuclear Ytterbium(I1) Complex { Yb[N(SiMe3)2l[μ -DAC]}2Yb. Inorg. Chem., 33, 1994, pp. 5302 – 5308.
[7] Sinelshchikova, A. A., Gorbunova, G. Y., Lapkina, L. A., Konstantinov, N. Y., and Tsivadze, A. Y. , Erbium Complexes with Tetra_15_crown_5_phthalocyanine: Synthesis and Spectroscopic Study. Russian Journal of Inorganic Chemistry, Vol. 56, No. 9, 2011, pp. 1370 – 1379.
[8] Rita, D., Judite, C., Krassimira, P. G., and Luis, M. P. L. , Lanthanide complexes of macrocyclic derivatives useful for medical applications. Pure Appl. Chem., Vol. 77, No.3, 2005, pp. 569 – 579.
[9] Taheri, K., Chamsaz, M., Rounaghi, G. H., and Ansari, M. F. , Study of complexes formation between La3+, Ce3+ and Y3+ cations with some 18-membered crown ethers in methanol – water and methanol – acetonitrile binary mixtures. J. Incl. Phenom. Macrocycl. Chem., 63, 2009, pp. 43 – 52.
[10] Bunzli, J. C. G. , Benefiting from the unique properties of lanthanide ions. Acc. Chem. Res. 39, 2006, pp. 53–61.

Abstract: Soils around painted buildings in Gboko and katsina-Ala (Benue state) and Ibi and Wukari (Taraba State) were collected and analysed for heavy metal contamination using standard methods. The study revealed that the level of contamination in Gboko and Katsina-Ala was in the order of Pb>Zn>Cd>Cr while for Ibi and Wukari the order was Pb>Cd>Zn>Cr. The levels of contamination of Mn, Ni and Cu in the soil samples around the painted buildings were low. The high contamination of the soil with lead is a serious threat to man especially the children who play with soils around the environment. Blood monitoring for lead and other metals is therefore recommended for individuals living in and around painted buildings.

Key words: blood monitoring , Contamination, Heavy metals, Painted buildings, soil.

[1]. Odoh R., Agbaji E.B, Kagbu J.A. and Thomas S. A.,(2011); Heavy Metal Speciation in Agricultural Farmland in some selected local government areas of Benue state, Nigeria. Scholars Research Library, Archives of Applied Science Research, 3 (3) 560-573.
[2]. Fergusson,J.E.(1990) Chemistry, Environmental impacts and Health Effects. Pergamon press oxford, 1990, 371-405.
[3]. Oluyemi,E.A.,Fenyit,G.J., Oyekunle,J.A.O and Ogunfowokan,A.O.(2008) Seasonal Variations in heavy metal concentrations in soil and some selected crops at a land fill in Nigeria. African Journal of science and Technology. 2(5):89-96
[4]. Logan T.J. and Miller R.H. (1983) Soil contamination analysis Res. Circ. Ohio Agric. Res. Dev.Ctr.Wooster. 275: 3-15
[5]. Ohio state University (nd) Background levels of heavy metals in Ohio farm soils.http://www.ohioline.osu.edu/rc275/rc275_1.html. Accessed on 18th June 2013.
[6]. W.H.O (World health Organisation),(1995) Evaluation of certain food additives and contaminants(Forty-first report of the joint FAO/WHO expert committee on food additives).WHO Technical report series No 837,WHO,Geneva.
[7]. Ratha,D.S., Venkataraman,G., and Pahala-Kumar,S (1994).Soil contamination due to open cast mining in Goa. A statistical approach to environmental technology.15:853-862
[8]. Fatoki, O.S. (1996) Trace Zinc and copper concentration in roadside surface soils and vegetation measurement of local atmospheric pollution in Alice, South Africa. Environment International, 22(6):759-762.
[9]. Ross, S.M (1994). Toxic metals in soil- plant systems. John Wiley ,New- York
[10]. Opaluwa,O.D and Umar,M.A (2010).Distribution and concentration of Heavy metal in some vegetables and soils from vegetable farms in Tudun Wada keffi, Nigeria. International journal of chemical sciences.3(1):71-77.

Abstract: The paper points to the presence of heavy elements such as cobalt, nickel, lead and cadmium ratios of small but very harmful to the environment as well as health harmful if used by people for agricultural purposes, etc. This is the heavy elements harmful if it exceeds the limit as it is then used as components of the value after the extract has found these elements mentioned sources such as Ismailia Canal - Manzala Lake and the Red Sea, has been used as comparison tap water ELM for the separation of these elements has been selected cobalt (III) dicarbolide Span surfactant 80/85 and the use of acid silicon tungestic stage stripping effect concentrations of the carrier and the amendment, has been selected Co(III) dicarbolide because metal organic compound with a larger surface area and the distinction between the structure of certain net structure.

Key words: (III) dicarbolide; Ismailia Canal - Manzala Lake; acid silicon tungestic; Span surfactant 80/85.

[1]. M.C. Basso, E.G. Cerrella, A.L. Cukierman, journal of, Industrial and Engineering Chemistry Research 41 (2002) 180–189.
[2]. D. Nabarlatz, J.D. Celis, P. Bonelli, A.L. Cukierman, Journal of Environment Management 97 (2012) 109–115.
[3]. A. Ewecharoen, P. Thiravetyan, E. Wendel, H. Bertagnolli, Journal of Hazardous Materials 171 (2009) 335–339.
[4]. Review on cadmium removal from aqueous solutionsnK.S. Rao1*, M. Mohapatra, S. Anand, P. Venkateswarlu, International Journal of Engineering, Science and Technology. 7 (2010) 81-103.
[5]. Henry Kasaini, Paul Thabo Kekana, Amirali Alizadeh Saghti, and Kim Bolton J. World Academy of Science, Engineering and Technology 76(2013)233-9.
[6]. Mphahlele, R.C.J., Bolton, K. & Kasaini, H. journal of, World Academy of Science, Engineering and Technology, 47(2010).
[7]. Gupta, S. S. & Bhattacharyya, K. G. Kinetics of adsorption of metal ions on inorganic materials: A review. Advances in Colloid and Interface Science, 162, (2011) 39-58.
[8]. H. F. Alya, A. K. Ghonaimb, S. Abdel-Wanesb & A. T. Kasema* Journal of Dispersion Science and Technology.7( 2012).
[9]. Marta kolodziejska. J. Physicochemical. Probl. Miner. Process. 49(1), 2013, 267−276.
[10]. SINGH R., MEHTA R., KUMAR V., J., Desalination, 272 (2011)170–173.

Abstract: Simultaneous multi-element graphite furnace atomic absorption spectrometer (SIMAA 6000) is used to get a new multi-element determinations methodology for Cu, Mn, and Se. Firstly, the optimum conditions for single-element mode are determined (which include: pyrolysis and atomization temperatures). Secondly, the optimum conditions for multi-element mode are also determined. The conditions in the two modes have been compared in terms of the characteristic masses, detection limits and pyrolysis and atomization temperatures. The effect of the matrix on the determination has been studied using urine standard sample from Seronorm (LOT 0511545). The accuracy of the developing methods has been confirmed by analysis different biological reference materials. Simultaneous multi-element GF-AAS offers a rapid, low cost and sensitive method for the analysis of trace elements.

Key words: Simultaneous multi-element Determination, Copper, Manganese, Selenium.

[1]. N-M Kuss, R Maibusch, and B Bayraktar, Trace Element Determination by means of Simultaneous Multielement Graphite Furnace
Atomic Absorption Spectrometry, Proceedings, XIVth Seminar on Atomic Spectrometry, High Tatras-Podbanske, 1998, 84-90
[2]. S Pi-guey and H Shang-Da, Direct and simultaneous determination of copper and manganese in seawater with a multielement
graphite furnace atomic absorption spectrometer, Spectrochim Acta Part B, 53, 1998, 699-708
[3]. H Man-Ching, S Yu-Hsiang, H Shang-Da, Direct and simultaneous determination of arsenic, manganese, cobalt and nickel in urine
with a multielement graphite furnace atomic absorption spectrometer, Talanta, 62, 2004, 791-799
[4]. S A Lewis and T C O,Haver, Determination of metals at the microgram-per-liter level in blood serum by simultaneous multielement
atomic absorption spectrometry with graphite furnace atomization, Anal. Chem., 57, 1985, 2-5
[5]. S A Lewis and T C O,Haver, Simultaneous multielement analysis of microliter quantities of serum for copper, iron and zinc by
graphite furnace atomic absorption spectrometry, Anal. Chem., 56, 1984, 1651-1654
[6]. K Kitagawa and Y Shimazaki, A simultaneous multielement atomic absorption spectrometer with an inverse polychromator and fast
fourier transformation, Analytical Sciences, 9, 1993, 663-669
[7]. C Chien-Ly, K Suresh Kumar Danadurai and H Shang-Da, Direct and simultaneous determination of coper, manganese and
molybdenum in seawater with a multi-element electrothermal atomic absorption spectrometer, J. Anal. At. Spectrom., 16, 2001,
404-408.

[8]. C Chun-Hao, S Yu-Hsiang, H Shang-Da, Simultaneous determination of manganese, iron and cobalt in copper with a multi-element graphite furnace atomic absorption spectrometer, Spectrochim acta part B, 58, 2003, 575-580
[9]. M Feuerstein and G Schlemmer, The simultaneous determination of Pb, Cd, Cr, Cu and Ni in potable and surface waters by GFAAS according to international regulations, Atomic Spectroscopy, 20 (4), 1999, 149-154
[10]. V R Amorim Filho, W L Polito, S R Oliveira, G P Freschi, J A Gomes Neto, Simultaneous determination of Cd and Pb in antibiotics used in sugar-cane fermentation process by GFAAS, Ecl. Quίm., Sau Paulo, 31 (2), 2006, 7-12.