Version-1 (Jul–Aug 2016)
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| Paper Type | : | Research Paper |
| Title | : | Plasma Proteins in Type 2 Diabetes Mellitus |
| Country | : | India |
| Authors | : | BN Malawadi || Usha Adiga |
Abstract: Introduction: Insulin resistance in type 2 diabetes mellitus is known to alter fractional synthetic rates of different plasma proteins. Objective of our study was to compare plasma total proteins and albumin in type 2 diabetics with that of non-diabetic controls. Methodology: This retrospective study was conducted in a medical college hospital in coastal Karnataka. Data of plasma proteins and demographic profiles of 81 type 2 diabetes mellitus patients was compared with that of 72 healthy non-diabetics. Student' s independent t test was used to compare the data.............
Key words: total protein, albumin, globulin, type 2 DM
[1]. Rehman A, Zamir S, Bhatti A, Jan SS, Ali S, Wazir F. Evaluation of albuminuria,total plasma proteins and serum albumin in diabetics.
Gomal J Med Sci 2012; 10: 198-200.
[2]. Taj Mohammad, Akbar Khoja, Khem A Karira, Abdur Harman. Comparison of Plasma Protein Concentration and Hematological
parameters in type-1 and type-2 Diabetics of short and long duration. Med channel Oct-Dec 2001; 7(4); 51-4.
[3]. American diabetes association(ADA).Standards of medical care in diabetes -2016.Diabetes care 2016; 39(1): S1-S106.
[4]. Schmidt MI, Duncan BB, Sharrett AR, Lindberg G, Savage PJ, Offenbacher S, Azambuja MI, Tracy RP, Heiss G: Markers of
inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study. Lancet
1999;353:1649 – 1652.
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| Paper Type | : | Research Paper |
| Title | : | Mir-221 in the Detection of Head and Neck Squamous Cell Carcinoma |
| Country | : | Pakistan |
| Authors | : | Obaid Hayat || Abdul Rauf Leghari || Muhammad Imran Sarwar || M.H Qazi || Bushra Nisar |
Abstract: Head and Neck Squamous cell carcinoma is the sixth most common cancer worldwide with increasing incidence in developing countries. Due to its late diagnosis and lack of availability of reliable biomarker for this disease, its incidence is still on rise. Aims & Objectives: The aim of this study was to characterize the role of miR-221 in the tumor genesis of Head and neck squamous cell carcinoma (HNSCC). The objective of the study was to analyze the expression profile of miR-221 in HNSCC..............
Key words: Head and neck squamous cell carcinoma, miR-221, Taqman assay, intra oral, extra-oral.
[1]. Dai, Y., Liu, Y., Huang, D., Yu, C., Cai, G., Pi, L., Ren, C., Chen, G.Z., Tian, Y., and Zhang, X. (2012). Increased expression of Rab coupling protein in squamous cell carcinoma of the head and neck and its clinical significance. Oncol Lett 3, 1231-1236.
[2]. Shibuya, K., Mathers, C.D., Boschi-Pinto, C., Lopez, A.D., and Murray, C.J. (2002). Global and regional estimates of cancer mortality and incidence by site: II. Results for the global burden of disease 2000. BMC Cancer 2, 37.
[3]. Jo, S., Juhasz, A., Zhang, K., Ruel, C., Loera, S., Wilczynski, S.P., Yen, Y., Liu, X., Ellenhorn, J., Lim, D., et al. (2009). Human papillomavirus infection as a prognostic factor in oropharyngeal squamous cell carcinomas treated in a prospective phase II clinical trial. Anticancer Res 29, 1467-1474.
[4]. Maru, D.M., Singh, R.R., Hannah, C., Albarracin, C.T., Li, Y.X., Abraham, R., Romans, A.M., Yao, H., Luthra, M.G., Anandasabapathy, S., et al. (2009). MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus. Am J Pathol 174, 1940-1948.
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| Paper Type | : | Research Paper |
| Title | : | Development of a suitable plant regeneration protocol of cotton cultivar variety in comparison to non cultivar Coker |
| Country | : | India |
| Authors | : | Nandini Bandyopadhyay || Soumitra Kr. Sen |
Abstract: We initiated our attempts with Coker-312(non cultivar) and other two cultivar varieties, Ankur-3 and JK-1. It was observed that genotype played an important role in callus induction and plant regeneration. Further, trials showed that kinetin played a major role in callus induction frequency. In case of JK-1, the MST2 calli became dull and unable to produce embryogenic calli leading to elimination of these genotypes from further consideration. The other two genotypes, responded favorably in callus proliferation and emergence of embryogenic calli. We had used charcoal in MSG media which helped in production of root system in normal looking plantlets. Hypocotyl, cotyledon and roots have been used in the past as explants, where hypocotyls produce more friable callus than other explants..............
Key words: Callus regeneration, Charcoal, Genotypes, KNO3, Somatic embryogenesis
[1]. Barwale RB, Gadwal RB, Zehr U and Zehr B (2004) Prospects for Bt cotton technology in India. Ag Bio Forum, 7 (1&2): 23-26. http://www.agbioforum.
[2]. Gould J, Banister S, Hasegawa O, Fahima M and Smith R (1991) Regeneration of Gossypium hirsutum and G Barbadense from shoot apex tissues for transformation. Plant cell rep. 10: 12-16.
[3]. Hemphill JK, Maier CGA and Chapman KD (1998) Rapid in vitro plant regeneration of cotton (Gossypium hirsutum L.) Plant Cell Rep. 17: 273-278.
[4]. Murashige T and Skoog F(1962) A revised medium for rapid growth and bio assays with tobacco tissue cultures. Physiol. Plant. 15: 473-497.
[5]. Gamborg O, Miller R and Ojima K (1968) Nutrient requirements of suspension cultures of soybean root cells. Exp. Cell. Res. 50: 151-158.
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| Paper Type | : | Research Paper |
| Title | : | Evolution of protein carbonyl content as a marker of AMI |
| Country | : | India |
| Authors | : | K. N. Kalaivanam || N.Santhosh Kumar || R. Bheemasen || Dinesha Ramadas |
Abstract: Reactive oxygen species modifies amino acid side chains of proteins such as arginine, glutamyl, lysine, threonine and proline to form protein carbonyls. Oxidative modification reaction leads to carbonylated proteins which appear as aldehyde or ketones in proteins. Protein carbonyl groups are rigorously related with cardiovascular diseases, as a sensitive marker of an acute inflammatory state and as an important index of oxidative stress. Measuring protein carbonyl associated with CVDs as oxidative protein damage is the primary aim of our study. This indicates carbonyl group formation and evidence of free radical modification of proteins............
Key words: AMI: Acute myocardial infarction, CVDs: Cardiovascular diseases, PC: Protein carbonyl, ROS: Reactive oxygen species
[1]. Ahmed IA, Myocardial-infraction based on intelligent techniques, Am J Applied Sci, 7, 2010, 349-351.
[2]. I. Peluso, G. Morabito, L. Urban, F. Ioannone, and M. Serafini, "Oxidative stress in atherosclerosis development: the central role of LDL and oxidative burst," Endocrine Metabolic & Immune Disorders Drug Targets, 12(4), 2012, pp. 351–360.
[3]. Isabella Dalle-Donne,a,, Ranieri Rossib, Daniela Giustarinib, Aldo Milzania, Roberto Colomboa, Protein carbonyl groups as biomarkers of oxidative stress, Clinica Chimica Acta, 329(1–2), 2003, Pages 23–38.
[4]. Santhosh Kumar, Mohammad Anwar, Balu Mahendran. K, Kalaivanam. K N, Significance of lipid profile estimation in patient with acute myocardial infarction, IJABPT, 4(2) 2013, 248-250.
[5]. Ramón Rodrigo,Matías Libuy, Felipe Feliú, and Daniel Hasson, Oxidative Stress-Related Biomarkers in Essential Hypertension and Ischemia-Reperfusion Myocardial Damage, Hindawi Publishing Corporation Disease Markers, 35(6),2013,773–790.
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| Paper Type | : | Research Paper |
| Title | : | Assessment of Oxidative Stress Among Type 2 Diabetes Mellitus Patients Attending in A Rural Teaching Hospital, Sangareddy |
| Country | : | India |
| Authors | : | Dr. Sarala Devi Tenepalli || Nagababu Pyadala |
Abstract: Background: Oxidative stress is associated with the poor glycemic control in diabetes mellitus. Severe oxidative stress may cause cellular inflammation and damaging blood vessels in type 2 diabetic patients. Objectives: The present study was aimed to assess oxidative stress among type 2 diabetic patients by estimating MDA along with the lipid profile and blood glucose. Materials and methods: The present study was carried out at MNR Medical college & hospital situated in Sangareddy, part of Medak District, Telangana state. The 80 study subjects were selected from the medicine ward of MNR hospital during the period from February 2016 to July 2016............
Key words: Oxidative stress, Malondialdehyde (MDA), Fasting blood sugar (FBS), Lipid profile, Type 2 diabetes mellitus,.
[1]. Diabtes.http://.who.int/mediacentre/factsheets/fs312/en/ index.html (Updated on November 2009).
[2]. Berry C, Tardif J C, Bourassa M G. Coronary heart disease in patients with diabetes: part I: recent advances in prevention and non invasive management. J.Am.Coll.Cardiol 2007; 49:631-42.
[3]. Sicree R, Shaw J, Zimmet P. Diabetes and impaired glucose tolerance. In: Gan D, editor. Diabetes Atlas. International Diabetes Federation. 3rd ed. Belgium: International Diabetes Federation 2006; p.15-103.
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[5]. David L.Nelson and Michael M.Cox. Oxidative phosphorylation and photophosphorylation .In :Lehninger's principal of biochemistry, Fifth Edition, India, Freeman, 2011.page no 720-721..
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| Paper Type | : | Research Paper |
| Title | : | The Use of Rauwolfia serpentina in Hypertensive Patients |
| Country | : | India |
| Authors | : | Ritu Soni || Sakshi Jaiswal || Jyoti Kiran Bara || Dr.Parul Saksena |
Abstract: The root of Sarpgandha is a species of flowering plant in the family Apocynaceae has been traditionally used in Ayurveda for many years to treat a variety of diseases that at first thought appear to bear little similarity to one another. These include insanity, epilepsy, insomnia, hysteria, eclampsia and hypertension. On reflection, however, these various diseases could have a common denominator if they were all relieved symptomatically by a sedative or a 'relaxing' drug such as Rauwolfia. In the fifty decade, its root gained popularity for its effect on hypertension...........
Key words: hypertension, sarpagandha, reserpine, Rauwolfia serpentina.
[1]. Singh R.K., Singh A., Rath S., Ramamurthy A., A review of Sarpgandha – whole herb v/s Reserpine –its Alkaloid in the
management of the hypertension, International Ayurvedic Medical Journal,3(2) , 2015, 565-569.
[2]. Kumari R., Rathi B., Rni A., Bhatnagar S., Rouvolfia Serpentina L. Benth :phytochemical , pharmacological and therapeutic
aspects, International journal of pharmaceutical sciences Review amd Research,23(2) , 2013,348-355.
[3]. Pandey V.P., Cherian E., Patani G., Effect of growth regulators and culture conditions on direct root induction of Rauvolfia
serpentina L. (Apocynaceae) Benth. by leaf explants, Tropical Journal of Pharmaceutical Research, 9(1), 2010, 27-34.
[4]. Prusoff W.H., Effect of reserpine on the 5-hydroxytryptamine and adenosinetriphosphate of the dog intestinal mucosa, British
Journal of Pharmacology, 17, 1961, 87-91.
[5]. Rolf S., Bruns H.J, Wichter T., Kirchhof P., Ribbing M., Wasmer K., Paul M., Breithardt G.,. Haverkamp W., Eckardt L., The
ajmaline challenge in Brugada syndrome: diagnostic impact, safety, and recommended protocol, European Heart Journal, 24(12),
2003, 1104-1112.
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| Paper Type | : | Research Paper |
| Title | : | A Study Of Thyroid Disorders Among The Patients Of Type 2 Diabetes Mellitus |
| Country | : | India |
| Authors | : | Gulab Kanwar || Monika Shekhawat || Suman Meena || Neeraj Saxena || Mahesh Chandra Mehra || Mohini Rathore |
Abstract: Diabetes Mellitus and Thyroid disorders are the most common endocrine diseases globally. These have been shown to mutually influence each other. Thyroid disorders, including both hypo- and hyper have been associated with insulin resistance due to various mechanisms. Level of Thyroid Stimulating Hormone (TSH) was measured. The study was carried out in Govt. Medical College and attached group of hospitals, Kota, Rajasthan. The study period was from January 2016 to June 2016 .A total of 124 Diabetic patients (type 2) were included in the study. The estimation of TSH was done in Department of Biochemistry, Govt. Medical College, Kota, Rajasthan , India...........
Key words: Diabetes Mellitus, Euthyroid, Hyperthyroid, Hypothyroid, Insulin Resistance, Thyroid Stimulating Hormone (TSH),
[1]. Motala A, Pirie FJ, Rauff S, Bacus HB. Cost-effective management of diabetes mellitus. Ethn Dis. 2006; Spring; 16(2 Suppl 2) : S2-79-84.
[2]. Barbara A. Ramlo-Halsted, and Steven V. Edelman. The Natural history of type 2 diabetes: Practical points to consider in developing prevention and treatment Strategies. Clinical diabetes. 2000; Spring ; VOL. 18. NO.2.
[3]. American diabetic association. Diagnosis & classification of diabetes mellitus. Diabetes care. 2006 Jan; 29 (suppl 1): 43 – 48.
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[5]. J. Feely and T. E. Isles. Screening for thyroid dysfunction in diabetics. BMJ.1979; June; 1(6179):1678.
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| Paper Type | : | Research Paper |
| Title | : | Anaerobic Biodesulfurization of Kerosene Part II:Investigating Its Kinetics |
| Country | : | Nigeria |
| Authors | : | Semiu Adebayo Kareem |
Abstract: Extensive research works have been carried out on biodesulfurization, especially which of dibenzothiophene as a model sulfur compound in petroleum. Recently, biodesulfurization of real petroleum feed, mostly diesel have been reported. The biodesulfurization of kerosene is hardly reported because it is mostly combusted domestically especially in sub-sahara Africa including Nigeria. The capability of Desulfatiglans anilini comb. nov..to desulfurize kerosene has been reported by authors elsewhere. This work examines the kinetics of kerosene biodesulfurization with and without the influence of mass transfer. The bio-kinetic parameters were estimated using the various methods of Hanes, Lineweaver-Buck and Eadie-Hofstee, all from the linear transformation of Michaelis-Menten equation..........
Key words: Bio-kinetic Parameters, Finite Difference Method, Linear Solvation Energy Relationships (LSERs), Log Mean Concentration Difference (LMCD) and Mass Transfer.
[1]. Kerr, R. A. (2000). A North Atlantic Climate Pacemaker for the Centuries. J. Sci.288(5473): 1984 – 1985.
doi:10.1126/science.288.5473.1984.
[2]. Monticello, D. J. (2000). Biodesulfurization and the Upgrading of Petroleum Distillates. Curr. Opin. Biotechnol; 11: 540 – 546.
[3]. Kareem, S. A. (2010). Kinetics of Biodesulfurization of Diesel and Kerosene. Ph.D. Thesis, Department of Chemical Engineering,
University of Lagos, Nigeria.
[4]. Zhang, S. H., Chen, H and Li, W. (2013). The Kinetic Analysis of Biodesulfurization of Model Oil Containing Multiple Alkyl
Dibenzothiophenes. Appl. Microbiol. Biotechnol.95 (7): 2193 – 2200 doi:10.1007/s00253-012-4048-6.
[5]. Xu, L., Peng, T., Zhang, D and Zhang, F. (2012). Fractal Desulfurization Kinetics of High-Sulphur Coal. Elsevier International Journal
of Mining Science & Technology.22 (1): 111 – 114. http://dx.doi.org/10.1016/j.ijmst.2011.07.01.
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| Paper Type | : | Research Paper |
| Title | : | Anaerobic Biodesulfurization of Kerosene Part I: Identifying a Capable Microorganism |
| Country | : | Nigeria |
| Authors | : | Semiu Adebayo Kareem |
Abstract: Kerosene is the main fuel for domestic use in Nigeria and some other developing countries. It is used in cooking in mostly in poorly ventilated kitchens. The combustion of kerosene produces oxides of nitrogen and sulfur which are precursors to acid rain which is known to destroy buildings, destroy vegetation and is also dangerous to human health. Desulfatiglans anilinicomb, novwas isolated from petroleum products contaminated soil and subsequently evaluated for its ability to desulfurize kerosene. Kerosene obtained from retail outlet in Lagos, Nigeria was provided as the sole source of sulfur in batch cultures and the extent of desulfurization after treatment determined............
Key words: Anaerobicbiodesulfurization, Desulfatiglans anilini comb, nov., Hydrodesulfurization, Biochemical and Morphological Characteristics.
[1]. Speight, J. G. (2000). The Desulfurization of Heavy Oil and Residua. New York N.Y. Marcel Dekker.
[2]. Linguist, L and Pacheco, M. (1999). Enzyme based Diesel Desulfurization Process offers Energy, CO2 Advantages. Oil Gas J. 97:45 – 48.
[3]. Grossman, M. J., Lee, M. K., Prince, R. C., Minak-Bernero, V., George, N and Pickering, I. J. (2001). Deep Desulfurization of Extensively Hydrodesulfurized Middle-Distillate Oil by Rhodococcus sp. ECRD-1. Appl. Environ. Microbiol.67 (4): 1949 — 1952.doi: 10.1128/AEM.67.4.1949 – 1952.2001
[4]. McFarland, B. C., Boron, D. J., Deever, W., Meyer, J. A., Johnson, A. R and Atlas, R. M. (2001). Biocatalytic Sulfur Removal from Fuels: Applicability for Producing Low Fuel Gasoline. Crit. Rev. Microbiol.; 24:99 – 147.
[5]. Monticello, D. J. (1998). Riding the Fossil Fuel Biodesulfurization Wave. Chem. Tech. 28 (7): 38 – 45.
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| Paper Type | : | Research Paper |
| Title | : | Clinical significance of Serum Amylase in Acute Organo phosphorus Poisoning |
| Country | : | India |
| Authors | : | Mr. Choperla SK SK Dattatreya Sitaram || Sumathi M.E |
Abstract: Introduction: OP compounds constitute heterogeneous category of chemicals used as pesticides. In this study we intend to know the clinical significance of serum amylase levels in OP poisoning cases at the time of admission in assessing the severity. Materials and Methods: A prospective observational study was conducted in a total of 36 clinically proven cases of OP poisoning. Serum amylase, lipase and Cholinesterase were measured at the time of admission. Patients were followed up for final outcome............
Key words: Amylase, Cholinesterase, lipase, Organophosphate poisoning
[1]. Yijaya Kumar S, Md. Fareedullah, Sudhakar Y, Venkateswarlu B and Ashok Kumar E, Current review on Organophosphorus poisoning, Archives of Applied Science Research, 2(4), 2010, 199-215.
[2]. Davie JOJ, Eddleston M and Buckley NA, Predicting outcome in acute organophosphorus poisoning with a poison severity score or the Glasgow coma scale, Q J Med; 101, 2008,371-379.
[3]. [3] Krupesh N, Chandrashekar TR and Ashok AC, Organophosphorus poisoning- still a challenging proposition, Indian J. Anaesth, 46 (1), 2002, 40-43.
[4]. Namba T; Nolte CT, Jackrel J, Grob D, Poisoning due to organophosphate insecticides, Am J Med, 50, 1971, 475 - 92.
[5]. Amanvermez R, Baydın A , Yardan T, Başol N and Günay M, Emergency Laboratory Abnormalities in Suicidal Patients with Acute Organophosphate Poisoning, Turk J Biochem, 35 (1), 2010, 29–34.
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| Paper Type | : | Research Paper |
| Title | : | Study of Biological Activities and Characterization of the Crude Orange Pigment isolated from A Distinct Salinicoccus Sp. MKJ997975 |
| Country | : | India |
| Authors | : | Bhakti Patel || Thankamani Marar || Manish Bhat |
Abstract: In the present study crude orange pigment isolated from a distinct Salinicoccus sp. MKJ997975 was investigated for antibacterial and antioxidant activity. Elucidation of the structural characteristic of the pigment was performed using the techniques of FTIR and NMR. Antibacterial activity using disc diffusion method for two gram negative and two gram positive bacteria concluded that the orange pigments did not show any toxicity. Radical scavenging activity by DPPH test for analysing antioxidant activity showed a good antioxidant property...........
Key words: Salinicoccus sp MKJ997975, Antibacterial, Antioxidant, orange, pigment, Peridinin, Pyrrhoxanthin.
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9(4), 2010, 635-639.
[2]. R.Rajendran and B.Thamarai Selvi, Natural Dyeing of Cotton Fabrics with Pigment Extracted from Roseomonas Fauriae, Universal Journal of Environmental Research and Technology, 4(1), 2014, 54-59.
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[5]. Kushwaha Kirti, Saini Amita, Saraswat Priti, Agarwal Mukesh Kumar, and Saxena Jyoti, Colorful World of Microbes: Carotenoids and Their Applications, Hindawi Publishing Corporation Advances in Biology.
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| Paper Type | : | Research Paper |
| Title | : | Comprehensive Study of Nano Cellulose Lignocellulosic Bionano Material |
| Country | : | India |
| Authors | : | Dr. Udai Pratap Singh |
Abstract: There has been an explosion of interest in the use of biomass as a source of renewable energy and material. Nano technology has been advancing rapidly in recent yearsby attaining prominence as nano- structured material, in the form nanocellulose material. The nanostructure of cellulose can play a significant part in pa- per making and high quality nano composites. It mainly consists of chemically cellulose nano crystals or mechanically extracted nanoparticles (micro fibrillated cellulose)............
Key words: Nanocellulose, lignocellulosic biomass, cellulose, hemi- cellulose, lignin.
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