Abstract: We report three cases of Posterior Reversible Encephalopathy Syndrome in different settings. First case was associated with systemic lupus erythematosus with gestational hypertension and lupus nephritis. Second case had no history of hypertension while third patient had only transient rise of blood pressure during & soon after an episode of seizures. All three cases had complete recovery. Posterior Reversible Encephalopathy Syndrome is a clinical-neuroradiological term, often associated with delayed postpartum eclampsia & classical imaging features usually in the form of bilateral, symmetrical, reversible white matter oedema involving commonly the posterior cerebral circulation. Diagnosing these lesions early & providing appropriate treatment is important to achieve an optimal neurological outcome.
[1] Williams Obstetrics book, 23rd edition, Pregnancy Hypertension, page 708-709.
[2] Sibai bm. Diagnosis prevention and management of eclampsia, Obstet Gynecol. 2005 Feb; 105(2):402-10.
[3] Lubarsky SL, Barton JR, Friedman SA, Nasreddine S,Ramaddan MK, Sibai BM, Late postpartum eclampsia revisited. Obstet Gynecol 1994;83:502–5.
[4] Felz MW, Barnes DB, Figueroa RE. Late postpartum eclampsia 16 days after delivery: case report with clinical,radiologic, and pathophysiologic correlations. J Am BoardFam Pract 2000;13:39-46
[5] Bartynski WS. Posterior reversible encephalopathy syndrome, part 1: fundamental imaging and clinical features, AJNR 2008;29(6):1036-42.
[6] V. L. Stott, M. A. Hurrell, T. J. Anderson, Reversible posterior leukoencephalopathy syndrome: a misnomer reviewed, Internal Medicine Journal 2005; 35: 83–90
[7] Bartynski WS, Boardman JF, Zeigler ZR, et al , Posterior reversible encephalopathy syndrome in infection, sepsis and shock. AJNR 2006; 27:2179-90.
[8] Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin MS, Lamy C, Mas JL, Caplan LR, A reversible posterior leukoencephalopathy syndrome, NEJM, 1996 Feb 22; 334(8):494-500.
[9] W.S. Bartynskia and J.F. Boardmana, Distinct Imaging Patterns and Lesion Distribution in Posterior Reversible Encephalopathy Syndrome, AJNR, August 2007; 28: 1320-1327
[10] Silvia Pugliese, V. Finocchi, M. L. Borgia, C. Nania, B. Della Vella, A. Pierallini , A. Bozzao, Intracranial hypotension and PRES: case report, J Headache Pain (2010) 11:437–440