Volume-6 ~ Issue-1
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|Paper Type||:||Research Paper|
|Title||:||Herbal Cures Practised By Rural Populace In Varanasi Region Of Eastern U.P.(India)|
|Authors||:||Sanjay Srivastava, C.O.Samuel|
Abstract: A survey based study to collect information regarding use of herbs as household treatment of common ailments in rural areas of Varanasi region of eastern U.P. was undertaken .In Varanasi as in other parts of India , the people especially those residing in rural and semi-urban areas still practise herbal cures for many of their ailments. In the present investigation a total of 40 medicinally important plant species belonging to 27 families were recorded which are frequently used by local populace to cure diseases such as cold,cough,fever,snake bite,boils piles etc.As plants are easily available and sometimes the only source of healthcare available to poor therefore there is a great need for preservation of such medicinal plants.
Keywords: Ayurvedic, healthcare, herbal cure ,medicinal plants.
[ Ben-Erik van Wyk and Michael Wink, Medicinal Plants of the World : an illustrated guide to important medicinal plants and their uses (Singapore:Times Edition,c2004).
 D.A.Possey and G.Dutfield, Beyond Intellectual Property : Towards Traditional Resource Rights for indigenous People and Local communities (Canada : International Development Research Centre,1996).
 E.M.Williamson, Major Herbs of Ayurveda (Churchill Livingstone,London,2002).
 J.F.Duthie, Flora of the upper Gangetic Plains (Government Printer,1903-1929).
 J.D.Hooker, The Flora of British India (L.Reeve and Company,London, Vol. I-VII,1872-1897).
 M.Giday, Z.Afsfaw, T.Elmqvist and Z.Woldu, An Ethnobotanical study of medicinal plants used by the Zay people in Ethiopia, Journal of ethnopharmacology 85, 2003, 43-52.
 S.Biswas, Rare and threatened taxa in the forest flora of Tehri Garhwal Himalaya and strategies for their conservation, Indian Journal of forestry II (3),1998, 233-237.
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Abstract: The present study was carried out to validate the anti-inflammatory and analgesic activities of Karuvilanchi ver chooranam (KVC) (Root powder of Smilax zeylanica) in rodents. Analgesic study was carried out by using Eddy's Hotplate method and acetic acid-induced writhing test and Anti inflammatory study was evaluated by Cotton pellet granuloma method and by plethysmometer method. The result of the analgesic activity evaluated using hot plate method revealed that the reaction time for mice was significantly increased in a dose dependent manner after one hour of oral administration. It was found that both KVC and Aspirin caused an inhibition on the writhing response induced by acetic acid. Doses of 250 and 500 mg/kg of the KVC and aspirin respectively, could completely block the writhing response exhibited about 61.51 and 72.51% inhibition. In acute inflammation model, the formalin induced paw oedema was significantly reduced by all the doses of KVC used when compared to control (P<0.05). The results of cotton pellet granuloma method indicated that KVC in both doses significantly reduced the weight of the cotton pellet granuloma with a dose dependent effect. From the result it can be concluded that the trial drug Karuvilanchi Ver Chooranam has potent analgesic and anti inflammatory properties which confirmed the traditional use.
Key Words: Analgesic, Anti inflammatory, Karuvilanchi ver chooranam, Siddha drug , Smilax zeylanica
. Ikram M, Economic potential of medicinal plants. Hamdard Medicus, 26:1983; 16-17.
. Hostettmann K, Bull Soc Fib Sc Nat, 76:1987; 51-63.
. Mohanraj, Vadha Noi Nidhanam 800. Edn 1,( A.T.S.V.S. Siddha medical college, Kanyakumari, Tamilnadu, 2008), 163.
. The wealth of India: A Dictionary of Indian Raw materials and Industrial products – Raw materials series, (Publication and information Directorate , CSIR, New Delhi, Reprints, 1999), 368.
. Kannusamy Pillai C. Chikitcha Rathna Deepam. Edn 3, Vol 1, (Thirumagal Press, Chennai, 1991), 30-31.
. OECD Guidelines For The Testing Of Chemicals For Acute Oral Toxicity 425– Up-And-Down-Procedure Adopted On 3 October 2008.
. Lipnick R.L., Cotruvo J.A., Hill R.N., Bruce R.D., Stitzel K.A., Walker A.P., Chu I., Goddard M., Segal L., Springer J.A., and Myers R.C. Comparison of the Up-and-Down, Conventional LD50 and Fixed Dose Acute Toxicity Procedures, Fd. Chem. Toxicol., 33, 1995,223-231
. Eddy, N.B., Leimback, D, Synthetic analgesics II Dithienylbutenyl and Dithenbutylamines, JPET, 107, 1953, 385-393.
. Turner RA, Screening Methods in Pharmacology, 2nd Ed. (New York, Academic Press, 1965,158.
. Collier, H.D.J., Dinnin, L.C., Johnson, C.A. and Schneider, CBr. J. Pharmacol. 32(2) , 1968 295.
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|Paper Type||:||Research Paper|
|Title||:||Parasites Associated with wild-caught houseflies in Awka metropololis|
|Authors||:||Nwangwu, U.C., Onyido, A.E., Egbuche, C.M, Iwueze, M.O. and Ezugbo-Nwobi, I.K|
Abstract: Investigation of parasites associated with wild-caught houseflies in Awka metropolis, Anambra State, southeastern Nigeria, was undertaken between April and August, 2012. Locally designed fly traps were used to collect flies. The flies were identified into genera and species using their characteristic features. These flies were demobilized by chilling, washed with sterilized distilled water, and the suspension homogenised before processing for parasites on their external body parts. For internal parasites, the external surfaces of the flies were sterilized with 70% alcohol, squashed to release the internal contents and the suspension homogenized with 100ml distilled water. Aliquots of the suspensions from both the internal and external contents of the flies were used for parasite isolations and identification using standard parasitological techniques. Eight fly species were processed for parasites identification. Parasites isolated from the flies were Entamoeba histolytica cysts, Hookworm ova, Ascaris lumbricoides ova, and Trichuris trichiura ova. All the parasites isolated were from the external surfaces of the flies. This reveals the fact that wild-caught flies, especially M. domestica, harbour parasites on their bodies, which can cause diseases. Hence, there is need for improved sanitation in our urban communities, to prevent epidemics associated with poor sanitary conditions.
Key words: Awka, Flies, Housefly, Parasites, Wild-caught.
. B.M. Che-Ghani, P. Oothuman, B.B. Hashim and B.I. Rusli, Patterns of hookworm infections in traditional Malaysia villages with and without JOICFP Integrated Project in Peninsular Malaysia-1989. Collected papers on the control of soiltransmitted helminthiases, Vol. V. APCO, Tokyo, 1993, Pp. 14-21.
. A. Montresor, D.W.T. Crompton, A. Hall, D.A.P. Bundy and L. Savioli, Guidelines for the evaluation of soil-transmitted helminthiasis and schistosomiasis at community level, 1998. WHO/CTD/SIP/98.1
. K.E. Mott, The World Health Organization and the control of intestinal helminths. Collected papers on the control of soil-transmitted helminthiases, Vol. IV. Tokyo: APCO, 1989, Pp. 189-200.
. A.C. Chandler and C.P. Read, Introduction to parasitology with special references to the parasites of man. 10th ed. (John Wiley & Sons; New York, 1962).
. S. Getachew, T. Gebre-Michael, B. Erko, M. Balkew and G. Medhin,. Non-biting cyclorrhaphan flies (Diptera) as carriers of intestinal human parasites in slum areas of Addis Ababa, Ethiopia. Acta Tropica. 103: 2007, 186-94.
. D.A.P. Bundy, A. Hall, G.F. Medley and L. Savioli, Evaluation measures to control intestinal parasitic infections. World Health Stat Q. 45: 1992, 168-79.
. K.P.F. Lai and C.K. Ow-Yang, Soil-transmitted helminthiasis in a rubber and oil-palm estate in Selangor Peninsular, Malaysia. Collected papers on the control of soil-transmitted helminthiases, Vol. V. Tokyo: APCO, 1993, Pp. 72-7.
. S. Yu, L. Xu, Z. Jiang, Q. Chai, C. Zhou and Y. Fang, Environmental and human behavioral factors in propagation of soil-transmitted helminth infections. In: Yokogawa M, et al, editors. Collected papers on the control of soil-transmitted helminthiases, Vol. V. Tokyo: APCO, 1993, Pp. 83-8.
. M.T. Anantaphruti, J. Waikagul, W. Maipanich, S. Nuamtanong and S. Pubampen, Soil-transmitted helminthiases and health behaviours among schoolchildren and community members in a west-central border areas of Thailand. Southeast Asian J Trop Med Public Health. 35: 2004, 260-6.
. W. Maipanich, S. Sanguankiat, S. Pubampen, T. Kusolsuk, W. Rojekittikhun and F. Castelli, Helminthic infections in a Tsunami-affected area: soil contamination and infection rates in the population. J Trop Med Parasitol. 30: 2007, 5-11.
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Abstract: Nyctotherus periplanetae is very common intestine dwelling ciliate in invertebrates. During the period of two years total number of 1842 intestinal samples of Periplaneta americana were checked. The percentage of prevalence of ciliates was found quite high and it was 57.77% during the year 2007 and 60.75% in 2008.
Key words- Periplaneta, Intestine, Nyctotherus, Prevalence
. Algamaliev, (1973): Observtion sur des nycthotherus des genres sicuopbora de puytorac and Grain Mestasicuphora gen N.et Parascicuophora Albert cilie parasites de batracienus anoeres
. Amero A and Sena, S. (1967a): Lista provisora des species do genero "Nyctotherus" Leidy, 1849 (Ciliatea Heterotrichida) Ates soc. Biol. Rio de Janeiro; 10(6): 149-151.
. Amero, A. and Sena, S. (1967a): Sobre a sistematica do genero: Nyctotherus" Leidy, 1849 (Ciliatea, Heterotrichida). Ibid; 11 (3): 119-120 J.protozol; 20: 51-57.
. Amoji, S. D. and Rodgi, S. S. (1970): A ciliates parasites Nyctotherus georgei n.sp.from the millipede Gongylorrhus sp. The Indian Zoologist, 1:81-86.
. Bhandari J. C. (2010): Studies on some Ciliate and Gregarine parasites of Annelida and Arthropoda
. Bhatia, B. L. (1936): The Fauna of British India, Protozoa, Ciliophora. Taylor and Francis, London.
. Bhatia, B. L. And Gulati A. N. (1972): On some parasitic ciliates from Indian frogs,toads earthworms and cockroaches. Arch Protistenk; 57: 85-120.
. Corliss, J. O. (2001): Two most remarkable amoeba men: Joseph Leidy (1823-1891) of Philadelphia and Eugene Penard (1855-1954) of Geneva Protist; 152: 69-85.
. Grasse,P. P. (1928): sur quelques Nyctotheres (Infusories heteroriches) nouveaux ou peu connus . Annuls Protist; 1: 55-98.
. Klein, B. M. (1958): The "dry" silver method and its proper use. J. Protozool. 5:99.
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Abstract: In this paper an inquiry was conceded away for segregation of some microorganisms from rhizosphere zone of tea from tea growing regions of Barak valley, Assam; India. The isolates were secluded from tea rhizosphere of Toklai varieties (TV17, 20, 23) from some tea estates of Barak valley. Five isolates were recognized up to their genre stage on the foundation of their morphological and biochemical distinctiveness and finally the appraisal of disorganize possibility against fungi Fusarium oxysporum was ascertained and spelled out.
Key words: ascertained, disorganize possibility, genus, rhizosphere, Toklai variety.
. Travers, R.S., Martin, P.A.W. and Reichelderfer, C.F. (1987). Selective process of efficient isolation of soil Bacillus spp. Appl. Environ. Microbiol. 53:1263-1266.
. Priyanthi.L.K.Teenakoon. (2007).Studies on Plant growth Promoting Microorganisms of Tea (camellia sinensis L. (o) Kuntze) Plants. Thesis submitted for partial fulfillment of the award of master degree in agricultural sciences in Agricultural microbiology. Department of agricultural Microbiology. College of Agriculture. University of Agricultural Sciences .Dharwad.
. Martin, J. P. (1950). Use of acid, Rose Bengal and streptomycin in the plate method for estimating soil fungi. Soil Sci. 69: 214-232.
. Dubey, R.C. and D.K, Maheshwari. (2002).A Textbook of Practical Microbiology.S.Chand & Co.Ltd, Ram Nagar, Newdelhi.pp.2-192.
. Gilman, J.C. (1957). A Manual of soil fungi.2nd ed. Lowa State College, Press. Amst, Iowa, USA. Pp: 450.
. Cappuccino, J.G.and Sherman, N. (2005). Microbiology: A Laboratory Manual.7th edition. Pearson.Inc. and Darling Kindesley publishing, Inc.
. Sakthivel, N.and. Gnanamanickam, S.S. (1987).Evaluation of Pseudomonas fluorescens for suppression of sheath rot disease and enhancement of grain yields in rice (Oryza sativa L.) .Appl. Environ.Microbiol.pp.2056-2059.
. Wei, G., Kloepper, J.W. and Tuzum, S. (1991).Induction of systematic resistance of Cucumber to Colletotrichum orbiculare by selected strains of plant growth promoting rhizobacteria.Phytopathol.81:1508-1512.
. Mariano, R.L. (1993). Métodos de seleção in vitro para o control e microbiológico de patógenos de plantas. Revisão Anual de Patología de Plantas. 1:369-409.
. V.Sanfuentes.,A.Gacitu,S.,P.Diaz,K.,C.Hernandez,J.,F.Valiente,C. and M.Uribe,M. (2009).Identification and Biological Characterization of Isolates with Activity Inhibitive Against Macrophomina phaseolina (Tassi) Goid. Chilean J. Agri. Research. 69(4): 526-533.
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Abstract:As previously work has been done on the isolation of free living nitrogen fixers from tea rhizosphere of South Assam, this edition was an additional work for verifying the nitrogen fixing ability of an isolate was an attempt to understand the nitrogenase activity of the isolate. In this paper an isolate has been isolated in a nitrogen free medium, it's morphological and biochemical assessments have been made earlier. And here its nitrogen fixation ability was depicted after doing Acetylene reduction Assay. From that a clear idea of its nitrogen fixing ability has been drawn, even if the capacity is low.
Key Words: Free living nitrogen fixers, nitrogenase activity, nitrogen free medium and Acetylene reduction Assay.
 .Capone, D. G. 1993. Determination of Nitrogenase Activity in Aquatic Samples Using the Acetylene Reduction Procedure, 621-631. In P. F. Kemp, B. Sherr, E. Sherr and J. Cole, [eds.], Handbook of methods in aquatic microbial ecology. Lewis Publishers.
. Dubey, R.C. and D.K, Maheshwari. (2002).A Textbook of Practical Microbiology.S.Chand & Co.Ltd, Ram Nagar, Newdelhi.1:2-192.
 Hardy, R.W.F., Holsten, R.D., Jackson, E.K. and Burns, R.C. (1968).The Acetylene-Ethylene Assay for Nitrogen Fixation: Laboratory and Field Evaluation. Plant Physiology.43:1185-1207.
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|Paper Type||:||Research Paper|
|Title||:||Antioxidant potential of Emblica officinalis (amla) aqueous extract delays cataractogenesis in hyperglycemic goat lenses|
|Authors||:||A.M Hajarnavis, P.M Bulakh|
Abstract: Aim: To study the antioxidant role of Emblica officinalis aqueous extract in delaying cataractogenesis in hyperglycemic goat lenses. Study design: Experimental study. Place and Duration of study: Department of Biochemistry, Bharati Vidyapeeth Deemed University Medical College, Pune, India, between February 2012 to June 2012. Methodology: Dried powder of Emblica officinalis fruit pericarp was obtained and crude water extract was prepared. Fresh goat lenses were removed from the eyeballs and divided into 3 groups as follows: Group I - Normal lenses ,incubated in Tissue Culture medium 199 (TC199), Group II & III- Experimental Cataract lenses incubated with TC 199 + 110mM Dextrose solution and TC 199 + 110mM Dextrose solution + 0.25% E.officinalis aqueous extract respectively. After 72 hours of incubation, lenses were homogenized in 0.1M sodium phosphate buffer, pH 7.4 and the supernatant was used for biochemical analysis. Effect of the extract on lens total soluble proteins, TBARS and antioxidant enzymes superoxide dismutase, glutathione peroxidase and glutathione reductase was statistically analyzed. Results: The lens total soluble proteins were maintained, TBARS were reduced and there was a significant rise in the activity of antioxidant enzymes SOD, glutathione peroxidase and glutathione reductase in the lenses incubated with the E.officinalis extract as compared to hyperglycemic lenses. Conclusion: The study highlights the antioxidant nature of E.officinalis which may play an important role in the prevention of hyperglycemia induced cataract.
Keywords: anticataract, antioxidant, E.officinalis, hyperglycemia, oxidative stress.
 Negahban K, Chern K, Cataracts associated with systemic disorders and syndromes. Curr Opin Ophthalmol. 2002;13:419–422.
 A Ceriello, Oxidative Stress and glycemic regulation. Metabolism, 2000 Vol. 49(2) : 27-29.
 JW Baynes, Role of oxidative stress in development of complications in diabetes. Diabetes 1991, Vol. 40: 405-412.
 DL Williams, Oxidation, antioxidants and cataract formation : a literature review, Veterinary Ophthalmology, 2006, Vol. 9 (5): 292-298.
 Jr Zigler JS, Lens Proteins: Principles and practice of Ophthalmology, Basic Science, (W.B.Saunders Co, Philadelphia), 1994, pp. 97-113.
 A, Wannemaker CF and Spector , Protein Synthesis in the core of the calf lens. Exp Eye Res, 1968,Vol. 7, p. 623.
 Lean ME, Noroozi M, Kelly I, Burns J, Talwar D, Sattar N & CrozierA. Dietary flavonols protect diabetic human lymphocytes against oxidative damage to DNA. Diabetes 1999.48:176-181.
 Marklund and Marklund, Involvement of superoxide anion radical in the autooxidation of pyrogallol and a convinient assay for superoxide dismutase. Eur J Biochem, 1974, Vol. 47, pp. 469-474.
 Paglia DE and Valentine WN. J.Lab. Clin Med, Vol. 70, p. 158.
 RJ Goldberg DM & Spooner, Methods of Enzymatic analysis( 3rd edition. Vol. 3) pp. 258-265.
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Abstract: The best strategy for management of obese, outside pharmacological interventions, is physical exercise associated to diet. Recent research has discovered that the problem of obesity is largely due to a biological clock and that lipid oxidation is higher in the evening compared to the morning and at night compared to day. The purpose of this study is to investigate the effect of time-of-day specific obese training on body composition and physical capacity in obese following a low calorie diet. 20 sedentary pre-obese and obese with a mean BMI of 34.3 kg/m2 aged 20 to 47 years subjects participated in a concurrent strength and specific endurance training for obese. Subjects were divided into two training groups: a Morning training Group (MG: n = 10) and an Evening training Group (EG: n=10). The specific training associated to lower caloric diet has increased physical capacity (17,7% for EG and 15,6% for MG), decreased body weight (7,3% for EG and 6% for MG) fat percentage (19,5% for EG and 11,3% for MG) and waist circumference (10,2% for EG and 8,2% for MG) in both groups. Afternoon training was more effective than morning training on fat loss (24.9% for EG versus 15.9% for MG) and on lean mass variation (+2.9% for EG versus -0.5% for MG).
Keywords: Obesity, Time of day Training, physical capacity, Body Composition
. P. T. James, N. Rigby, and R. Leach, International Obesity Task Force The obesity epidemic, metabolic syndrome and future prevention strategies, Eur. J. Cardiovasc. Prev. Rehabil, 2004, 11, 3–8.
. NHLBI, Obesity Task Force Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-the evidence report, Obes. Res, 1998, 6, 51S–209S.
. A. Basdevant, L'obésité : origines et conséquences d'une épidémie, Comptes Rendus Biologies, August 2006, volume 329, issue 8, pages 562–569.
. A. Basdevant, Obesity: Pathophysiological concepts, Joint Bone Spine, 2008, vol 75, p 665-666.
. A. Basdevant, B. Guy-Grand, Médecine de l'obésité. Flammarion – Médecine Sciences, 2004, vol 1, p 431.
. G.A Bray, L.A. Tartaglia, Medical strategies in the treatment of obesity, Nature 404, 2000, page 672-677.
. M. Merrouche, B. Coffin, Obésité : prise en charge, indication et méthode de traitement endoscopique et chirurgical, EMC- HEPATHO-Gastroentérologie, July 2005, volume 2, issue 3, page 189-200.
. F. Brandou, M. Dumortier, P. Garandeau, J. Mercier, J.F. Brun, Effects of two-month rehabilitation program on substrate utilization during exercise in obese adolescents, Diabetes Metab, 2003, 29, 20-7.
. O. Ben Ounis, M. Elloumi, M. Amri, Y. Trabelsi, G. Lac, Z. Tabka, Impact of training and hypocaloric diet on fat oxydation and body composition in obese adolescents. Sci Sports, 2009, volume 24, issues 3–4, pages 178-185.
. S. Lazzer, Y. Boirie, C. Montaurier, J. Vernet, M. Meyer, M. Vermorel, A weight reduction program preserves fat-free mass but not metabolic rate in obese adolescents. Obes Res, 2004, 12 (2), 233-40.
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Abstract: Regular exercise is one of the most used solutions to avoid obesity. In this study we compared the amounts of lipid oxidation and the level of perceived exertion in three physical exercises, one continuous and two intermittent in obese. Ten obese men (age 26.01 ± 6.0 years, weight: 104.2 ± 19.4 kg, BMI: 33.5 ± 3.6 kg / m2) performed three 45 minutes exercises during which we measured energy expenditure and the level of perceived exertion. A continuous exercise whose intensity corresponds to the intensity of Fat max, an intermittent exercise which alternate four minutes at the intensity of Fat max -10% and one minute at the fat max intensity +10% (intermittent 1/4), and a second intermittent exercise which alternate two minutes at the intensity of Fat max -10% and one minute at the Fat max intensity +20% (intermittent 1/2). While the total energy expenditure during continuous exercise (321.6 Kcal) is higher than those of the intermittent 1/4 (268.1 Kcal) and the intermittent 1/2 (268.9 Kcal), the amounts of energy from oxidized fats in the three exercises are equivalent: 34,6 Kcal, 31,8 Kcal and 36,2 Kcal respectively for the three exercises. The perceived exertion measured by the Borg scale showed that intermittent exercises causes less fatigue in obese than the continuous exercise.
Keywords: Obese, exercise form, fat expenditure, perceived exertion
 F. Samguigol, Obesity: A Chronic multifactorial disease, Physiotherapy, review, Volume 8 issue, in April, 2008, pages.14-16.
 C. Emery, J. Dinet, A. Lafuma, C. Sermet, B. Khoshnood, F. Fagnani, Evaluation of stroke associated with obesity in France, Metabolic disease medicine, Volume 1 issue 2 June 2007, Page 28-34.
 C.A. Dour, T. M. Horacek, S. M. Schembre, B. Lohse, S. Hoerr, K. Kattelmann, A. A. White, S. Shoff, B. Phillips, G. Greene Process Evaluation of Project WebHealth: A. Nondieting Web-based Intervention for Obesity Prevention in College Students. J Nutr Educ Behav. 2013, Feb 11.
 M. C. Kegler, D. W. Swan, I. Alcantara, L. Feldman, K. Glanz, The Influence of Rural Home and Neighborhood Environments on Healthy Eating, Physical Activity, and Weight.Prev Sci. 2013, Feb 14.
 M. MERROUCHE, B. Coffin. Obesity treatment, indication and method of Endoscopic and surgical treatment, EMC-Hepatho Gastroenterology, Volume 2, issue 3 July 2005, page 189-200.
 C. Grondard, F. Charbonnier, J. P. Gasc, P. P. Vidal, C. L. Gallien, C. Canon, Biological responses to training: data cineradiography. Science & Sports vol. 20 Issue 4 August, 2005. p. 232-234.
 J. K. Zakrzewski, K. Tolfrey, Comparison of fat oxidation over a range of intensities during treadmill and cycling exercise in children, Eur J Appl Physiol, 2012 Jan;112(1):163-71.
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|Paper Type||:||Research Paper|
|Title||:||Estimation of G6pd Status in the Rajbangshi Population of Sushrutanagar|
|Authors||:||Anindya Dasgupta, Tanushree Mondal, Asok Kumar Datta|
Abstract: The Glucose 6 Phosphate Dehydrogenase (G6PD) deficiency renders the cells susceptible to severe hemolysis under oxidative stress producing conditions. Due to considerable genetic heterogeneity it is found to be distributed in an unequal manner in different parts of the world including India. The present study was undertaken to find the distribution of G6PD deficiency in the Rajbangshi population group of Sushrutanagar, Darjeeling district. The Rajbangshis are one of the oldest tribes residing in North Bengal. A quantitative assay of the G6PD activity was performed in the Rajbangshi population and the non Rajbangshi control population of the same area. The G6PD deficiency was found in 12 percent of the Rajbangshi population studied which is significantly higher than the value of 3.3 percent found in the controls with the lower and upper confidence limit for the population Odds ratio being 3.58 and 25.93 respectively at 95% confidence interval. This high rate of G6PD deficiency in the population group studied poses them to a greater risk for several oxidative stress producing conditions including some commonly used antimalarial drug like Primaquin.
Key Words : Glucose 6 Phosphate Dehydrogenase (G6PD) deficiency, Rajbangshis, Ethnicity
. Vasudevan, D.M. and Srikumari, S. (1998), Text Book of Biochemistry for Medical Students, 2nd edn. Jaypee Brothers Medical Publishers Ltd., New Delhi, p 59.
. Ghai, O.P. (2001), Essentials of Paediatrics, 5th edn. Mehta Publishers, New Delhi, p 102-103.
. Vasudevan, D.M. and Srikumari, S. (1998), Text Book of Biochemistry for Medical Students, 2nd edn. Jaypee Brothers Medical Publishers Ltd. New Delhi, p103-104.
. Wendell, Ross. and H, Franklin Bunn. (2001), Harrison‟s Principle of Internal Medicine, vol 1,15th edn. (International edition). MCgraw Hills, Singapore, p 685.
. Vasudevan, D.M.and Srikumari, S. (1998), Text Book of Biochemistry for Medical Students, 2nd Edition. Jaypee Brothers Medical Publishers Ltd. New Delhi, p 305.
. Cai, W., Filosa, S., Martini, G. (1994), DNA haplotypes in the G6PD Gene Cluster studied in the Chinese Li Population and their relationship to G6PD. HumHered. 44 (5), 279-86.