Volume-1 ~ Issue-6

Abstract: Solid complexes of 5-C-prenylgallacatophenone having general formula [M (C13H15O4)3] {Where M = La(III), Pr(III), Nd(III) & Tb(III)} are prepared and characterized by elemental analyses, I R., diffuse reflectance spectra, 1HNMR and thermal decomposition studies. They are found to have octahedral geometries. The complexes undergo thermal decomposition involving random nucleation mechanism. The evaluation of thermal kinetic parameters (E&Z) by using non isothermal method is reported.
Key words: Characterization, kinetic parameters, decomposition, complexes.

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Abstract :A two-step process for the synthesis of tribromomethyl-substituted cyclopropanes is described.
Halothane, an anesthetic agent, is added to olefins in a ruthenium-catalyzed reaction. The resulting 1,3-
dihalides are converted into cyclopropanes by dehalogenation with magnesium. This procedure represents an
alternative to metal-catalyzed cyclopropanations involving tribromomethyl diazomethane.

[1] O'Hagan, D. J. Fluorine Chem. 2010, 131, 1071– 1081
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Abstract: Soil samples were collected from floodplain sediment in Enugu Urban, Nigeria to investigate the speciation and bioavailability of some trace metals, namely; iron, manganese, copper, zinc, lead, nickel and cadmium. Extracts from the soil were obtained by sequential extraction as described by Horowitz et al. The metals occurred with the following percentage bioavailability: Fe(67.00%), Mn(65.10%), Cu(44.70%), Zn(52.90%), Pb(53.80%), Ni(53.90%) and Cd(8.30%). Exchangeable metals and metals bound to carbonates accounted for over 50% of the total fractions. Metals bound to Fe-Mn oxides and humic materials accumulated 4.50% and 7.96% respectively, while residual metals bounded 34.93% of the sediment fraction. Lead had the highest distribution in exchangeable, carbonate and residual fractions while zinc was partitioned mostly in reducible and oxidizable forms. The high concentration of lead in both the carbonate and exchangeable forms depict its greater mobility tendency in the soil and consequently, bioavailable to biota. The results of the finding indicated that these trace metals with exception of cadmium were readily bioavailable in this urban soil, therefore, phytoremediation is advocated.
Keywords: Speciation; Trace metals; Floodplain sediments; Bioavailability; Pollution.

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Abstract: The interaction of Cu (II) metal ion complex with Rubeanic acid has been studied at various ionic strengths PH - metrically. The values of Pk [Proton - Ligand stability constant] and log k [Metal - Ligand stability constant] are utilised to estimate the thermodynamic stability constant at zero ionic strength and to know the exact nature of complexation equilibria. Pk/log k values are found to be increasing with decreasing the values of ionic strengths. Key words: Cu (II), Dithio-oxamide [Rubeanic acid] Ethanol.

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Abstract: The corrosion inhibition efficiency of Schiff base, 3-formylindole-3-aminobenzoic acid (3FI3ABA) on mild steel (MS) in 1.0 M HCl solution have been investigated using weight loss measurements, electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization studies. 3FI3ABA exhibited good inhibition on mild steel in HCl medium even at low concentrations and the inhibition efficiencies increases with increase in concentration of the inhibitor. The adsorption of inhibitor on the surfaces of the corroding metal obeys Langmiur isotherm. Polarization studies revealed that 3FI3ABA act as a mixed type inhibitor. Thermodynamic parameters (Kads, ΔG0 ads) were calculated using Langmiur adsorption isotherm.
Keywords: Corrosion inhibitors, Impedance. Isotherm, Mild Steel, Schiff base,

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[4] A. Yurt and Özlem Aykın, Diphenolic Schiff bases as corrosion inhibitors for aluminium in 0.1 M HCl: Potentiodynamic polarisation and EQCM investigations, Corrosion Science, 53(11), 2011, 3725-3732.
[5] A. K. Singh, S. K. Shukla, M. Singh and M.A. Quraishi, Inhibitive effect of ceftazidime on corrosion of mild steel inhydrochloric acid solution, Materials Chemistry and Physics, 129(1), 2011, 68-76.
[6] M. Behpour, S.M. Ghoreishi, N. Soltani, M. Salavati-Niasari, M. Hamadanian and A. Gandomi, Electrochemical and theoretical investigation on the corrosion inhibition of mild steel by thiosalicylaldehyde derivatives in hydrochloric acid solution, Corrosion Science, 50(8), 2008, 2172-2181.
[7] K. Stanly Jacob and G. Parameswaran, Corrosion inhibition of mild steel in hydrochloric acid solution by Schiff base furoin thiosemicarbazone, Corrosion Science, 52(1), 2010, 224-228..
[8] S. Deng, X. Li and H. Fu , Alizarin violet 3B as a novel corrosion inhibitor for steel in HCl, H2SO4 solutions Corrosion Science, 53(11), 2011, 3596-3602.
[9] S. John and A. Joseph, Electro analytical, surface morphological and theoretical studies on the corrosion inhibition behavior of different 1,2,4-triazole precursors on mild steel in 1 M hydrochloric acid, Materials Chemistry and Physics, 133(2), 2012, 1083-1091.
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Abstract: The introduction and removal of protecting groups can play an important role in organic and natural product synthesis.The synthesis of dimethyl acetals of carbonyl compound such as cyclohexanone has successfully been carried out by the reaction between cyclohexanone and methanol using different transition metals modified mesoporous ceria catalysts. The strong influence of the textural properties of the catalysts such as acid amount and adsorption properties (surface area and pore volume) determine the catalytic activity. We introduced a mild and selective reagent for the oxidative cleavage of acetals under aqueous and heterogeneous conditions.The stability, simple work-up and high yields of the products are among the advantages of this procedure which make it an attractive supplement to the present reported methods. Keywords: dimethyl acetals, deprotection of acetals, catalytic activity, transition metals modified mesoporous ceria

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Abstract: A wide range of minerals are found in the soil as natural occurring and purposely added elements as well as by adventitious contamination. These mineral elements can generally be classified as nutritionally essential major elements, nutritionally essential minor and trace elements, and those regarded as toxic with an essential/toxic duality. An investigation was carried out regarding the concentrations of some of these nutritionally essential elements in the soil samples from Akanu Ibiam Federal Polytechnic, Unwana, Nigeria. The results revealed the presence of some of these mineral elements studied in moderate concentrations in the locations sampled. The study also showed that the institution soil is of low fertility and therefore recommend the use of fertilizers to improve its fertility and hence increase crops yield. Keywords: Unwana soil, mineral elements, fertilizers, nutrient deficiency, agricultural yield.

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Abstract : The Canavalia ensiformis used for this study was cultivated and harvested in Owo, Ondo state of Nigeria. The seed was prepared by sun drying for two weeks; it was later dehulled and milled to flour. The proximate and the mineral compositions of the seed were investigated using standard analytical techniques. The oil in the seed was extracted using solvent extraction method. The resulting crude oil was assessed for physicochemical parameters and fatty acid composition. Canavalia ensiformis contains high protein content, high carbohydrate content, high fibre content, low lipid and adequate minerals. The oil was bright in colour, transparent with low thermal stability when in contact with air. The free fatty acid and acid value was low, have high iodine and peroxide values, and low saponification value. Oleic acid has the highest fatty acid composition with 32.88%, followed by Linoleic acid with 25.93%. The total saturated fatty acid was 8.41%, while the total unsaturated fatty acid was 86.49%. Having considered the proximate and mineral compositions, the study revealed that the seed have high potential for animal and human consumption. In addition, it compared favourably with some conventional edible legumes. The oil, if refined and consumed will supply essential fatty acid to the body based on the fatty acid composition. Keywords: Canavalia ensiformis, Physicochemical, Mineral, Proximate, Oil

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Abstract: The aim of this review was to collate literature work reported by many researchers on Dibenzazepine derivatives for their varoius pharmacological activities and also to report the recent efforts made on this moiety. This interesting group of compound has diverse biological activities such as antimicrobial, antimyobacterial, antiviral, analgesic, anticonvulsant, antidepressant, anticancer, antidiabetic, antioxidant. The purpose of this review is to provide an overview of diverse pharmacological activities of Dibenzazsepine . Various derivatives of Dibenzazepine have been analysed in this review for varying pharmacological activities.
Key Words: Dibenzazepine derivatives, antiviral, anticancer, anticonvulsant, antimicrobial, antidepressant .,

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Abstract: In this study, the synthesis of fatty acid – carbohydrate esters used glucose (G) and coconut oil fatty acid (FA). The esterification reaction was carried out enzymatically using Candida rugosalipase in organic solvent (n-hexane). Lipase was immobilized on Ca-alginate gel beads withthe optimum condition for immobilization was1 % of Na-alginate, resulting 61.66% immobilization yield. The optimum conditions for esterification using immobilized lipase in Ca-alginate were at 35oC, the molar ratio 1:60 (G/FA), 16 hours incubation time and 0 g molecular sieve. Characterization of synthesized product with FT-IR showed that product exhibit the absorbtion of ester functional group at 1737 cm-1, but with thegreater OH groupabsorption peakat3344.57cm-1indicatedthat the degree ofesterificationwas still low. The synthesized product was then examined by simple emulsion test and was proved to be an emulsifier. Based on theemulsion test, it was known that theproducts ofthe reactionwereglucoseestersthat have propertiesampiphilicas anemulsifiersystem ofoil-in-water emulsion(o/w).
Keywords: glucose ester, Candida rugosalipase, lipase immobilization, Ca-alginate,coconut oil fatty acid

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[7]. Öztürk, Banu. (2001). Immobilization of Lipase from Candidarugosa onHydrophobic and Hydrophilic Supports. Đzmir Institute of Technology,Turkey.
[8]. Won, K., Kim, S., Kim, K.-J., & Park, H. W. (2005). Optimization of Lipase Entrapment in Ca-alginat gel beads. Process Biochemistry 40 , 2149-2154.
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Abstract: Transition metal complexes have emerged as promising candidates for therapeutic applications, owing to their diverse chemical properties and potential benefits in medicine. This paper aims to explore the burgeoning field of therapeutic applications of transition metal complexes, highlighting their significance and recent advancements. Initially, it offers a comprehensive overview of the fundamentals of transition metal complexes, elucidating their chemical nature, coordination chemistry, synthesis methodologies, and characterization techniques. By understanding these fundamentals, researchers can effectively design and manipulate transition metal complexes for specific therapeutic purposes. Furthermore, this paper delves into the therapeutic applications of transition metal complexes, focusing on their role in combating various diseases. Notably, transition metal complexes.........

Keywords: Transition metal complexes, therapeutic applications, anticancer, antimicrobial, anti-inflammatory, drug design, challenges, future prospects

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