Version-1 (May-June 2018)
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| Paper Type | : | Research Paper |
| Title | : | HsCRP And Serum Zinc Levels In Type 2 Diabetes Mellitus And Their Correlation With GLYCEMIC Status |
| Country | : | India |
| Authors | : | Dr .Mamatha B.V || Dr. Leela P || Dr. Chandrakanth K.H || Dr. Kashinath R.T |
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: | 10.9790/264X-0403010104  |
Abstract: Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder in which prevalence has been increasing steadily all over the world. Type 2 DM represents a significant global health problem. Metabolically triggered inflammation has been proposed as a key step in the pathogenesis of this disease and accelerate atherosclerosis and premature death in subjects. C-reactive protein is an acute phase reactant protein., which is found elevated and serum zinc levels are lower in T2DM. Objectives: To estimate hsCRP (high sensitivity C reactive protein) and serum zinc levels in cases and controls and to compare and analyze the levels of these parameters between two groups............
Key words: T2DM; hsCRP; serum Zinc ; inflammation ; Oxidative stress.
[1]. Abdulfatai B. Olokoba, Olusegun A. Obateru, Lateefat B. Olokoba . Type 2 Diabetes Mellitus: A Review of Current Trends. Oman Medical Journal (2012) Vol. 27, No. 4: 269-273
[2]. Amanullah S, Jarari A , Govindan M , Basha MI and khatheeja S. Association of hs-CRP with Diabetic and Non-diabetic Individuals. JJBS 2010Jan;3(1);7-12.
[3]. Badawi A , Klip A, Haddad P, Cole DE, Bailo BG, Sohemy AE, Karmali M. Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention, Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2010;3:173–86.
[4]. Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus. JAMA 2001July;286(3).
[5]. Haque AF, Ekram AS, Islam QT, Jahan S, Haque Z. Evaluation of serum high sensitivity c -reactive protein (hs-CRP) in type-2 diabetic patient. J Medicine 2010; 11:20-3.
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| Paper Type | : | Research Paper |
| Title | : | Antimicrobial Activity Of Murraya Koenigii And Zingiber Officinale Plants On Drug Resistant Pathogens Isolated From Clinical Specimens And Preliminary Phytochemical Analysis Of The Crude Extract Preparations |
| Country | : | India |
| Authors | : | Nagesh Malik || Samreen Ahmed |
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: | 10.9790/264X-0403010510 |
Abstract: The aim of the present study was to investigate the antimicrobial activity and phytochemical screening of Murraya koenigii and Zingiber officinale plant extracts. Ethanol and Methanol were used as the solvents for extraction. The antimicrobial activities of these plant extracts were tested against the drug resistant Gram-positive and Gram-negative bacterial strains. The bacteria used in the study were Staphylococcus aureus, Staphylococcus epidermidis, Acinetobacter baumannii, Salmonella spp., Proteus mirabilis, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecium and Neisseria spp. The ethanol and methanol extracts of leaves of Murraya koenigii and rhizome extracts of Zingiber officinale showed promising results against the drug resistant pathogens with zone diameter of inhibition more than 15mm. The ethanol extracts gave larger zones of inhibition than methanol extracts...........
Key words: Antibacterial activity, Drug resistant pathogens, ethanol, methanol, Phytochemical screening
[1]. Alo, M. N, Anyim, C., Igwe, J. C., Elom, M. and Uchenna, D. S. 2012. Antibacterial activity of water, ethanol and methanol extracts of Ocimum gratissimum, Vernonia amygdalina and Aframomum melegueta. 3:844-848.
[2]. Bipul Biswas, Kimberly Rogers, Fredrick McLaughlin, Dwayne Daniels and Anand Yadav. 2013. Antimicrobial Activities of Leaf Extracts of Guava (Psidium guajava L.) on Two Gram-Negative and Gram-Positive Bacteria. 2013:7.
[3]. Chang-Geun Kang, Dae-Sik Hah, Chung-Hui Kim, Young-Hwan Kim, Euikyung Kim and Jong-Shu Kim. 2011. Evaluation of Antimicrobial Activity of the Methanol Extracts from 8 Traditional Medicinal Plants. 27:31-36.
[4]. Chitra Wendakoon, Peter Calderon and Daniel Gagnon. 2011. Evaluation of Selected Medicinal Plants Extracted in Different Ethanol Concentrations for Antibacterial Activity against Human Pathogens. 1:60-68.
[5]. David G.White, Shaqua Zhao, Robert Sudler, M.S., Sherry Ayers, Sharon Friedman, Sheng Chen, Patrick F. Mcdermott, Shawn Mcdermott, B.S., David G. Wagner and Jianghong Meng. 2001. The Isolation of Antibiotics-Resistant Salmonella from Retail Ground Meats. 345.
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| Paper Type | : | Research Paper |
| Title | : | Apolipoproteins: Risk Assessment Tools For Coronary Heart Disease |
| Country | : | India |
| Authors | : | Dr.Leela .P || Dr.Mamatha .B.V || Dr.Chandrakanth .K.H || Dr.Kashinath .R.T |
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: | 10.9790/264X-0403011115 |
Abstract: Myocardial Infarction (MI) is one of the major causes of morbidity and mortality in the world. Dyslipidemia is one of the important risk factor. It initiates atherosclerotic plaque formation, finally resulting in degeneration of endothelial cell function which enhances the coagulability of blood by activation of various factors for which apolipoproteins have been implicated. Apolipoprotein A-1 (apo A1) and apolipoprotein B (apo B) are the protein constituents of high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C), respectively. Apo A-1 and HDL-C are antiatherogenic whereas Apo B and LDL-C are atherogenic. Objectives: To evaluate and to compare the serum concentrations of apo A1, apo B and lipid profile between Coronary Heart Disease (CHD) patients and healthy subjects and to establish interrelationship if any, between apolipoproteins and lipid profile in CHD patients............
Key words: Coronary heart disease, apolipoprotein, lipid profile, dyslipidemia.
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[2]. Rifai N, Warnick GR. Lipids, lipoproteins, apolipoproteins and other cardiovascular risk factors. In: Burtis CA, Ashwood ER and Bruns DA, editors. Tietz Text Book Of Clinical Chemistry and Molecular Diagnostics, 4th ed. New Delhi: Elsevier Co;2006:903-64.
[3]. Sharma R, Singh VS. Serum apolipoproteins in the patients of myocardial infarction in different age groups. Ind J ClinBiochem 2001;16(1):122-26.
[4]. Rifai N, Bachorik PS and Albers JJ. Lipids, lipoproteins, apolipoproteins and other cardiovascular risk factors. In: Burtis CA, Ashwood ER and Bruns DA, editors. Tietz Fundamentals of Clinical Chemistry, 5th ed. New Delhi: Elsevier Co;2006:903-64.
[5]. Irshad M, Dubey R. Apolipoproteins and their role in different clinical conditions: An overview. Indian Journal of Biochemistry & Biophysics 2005 April;42:73-80.