Volume-15 ~ Issue-1 ~ January 2022

Abstract: Metal complexes of β – diketones: pentane – 1, 3 – diketones (Hpd), 1, 1, 1 – trifluoropentane – 1 ,3 – dione(Htfpd), 4, 4, 4 – trifluoro(2 - thienyl)butane – 1, 3 –dione (Htftbd), and 2 - thenoyltrifluoroacetone (Htta) in the studies examined have rate constants (kMHE) values lower than the rate of water exchange by several orders of magnitude, However, the Eigen Wilkinson trend: Cu2+ Co2+ Ni2+ Fe3+ was identified with some of the β – diketonates. Substituents effects were not important in the rate determining steps as the rate constant of most metal ions do not change significantly on varying the ligands. However, in mono, di and tri-metallic β – diketonates complexes of the type [M(RCOCHCOR), varying R have significant effect on the reaction rate and labile β – diketones were found to significantly influence reaction rates compared to reactions where the β – diketones are non – labile.

Key worlds: Eigen Wilkinson constant, protonated ligands, labile and non – labile β - diketone

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Abstract: Cu(I) catalysed 1,3-dipolar cycloaddition combination of azide and alkyne yielded a novel chemical series of [1,2,3]-triazole containing benzoxazine derivatives. In vitro testing of the produced drugs for antibacterial activity revealed that compounds 6a, 6i, 6j and 6k are effective antibacterial agents. Among these four compounds are the most common 3-((1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl)-2,2-dimethyl-2,3-dihydro-4H-benzo[e] [1,3] oxazin-4-one (6j) compound has shown the most powerful antibacterial action against gram negative and gram positive bacterial strains tested.

Keywords: 1,3- Benzoxazin-4-one, 1,2,3-triazole,in vitro antibacterial activity

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Abstract: The research work was conducted to assess the effect of methanol, ethylacetate and n-hexane fraction extracts of combretum obanense on ethanol-induced gastric ulcer in rats and also to assess the phytochemical constituent of the plant for identification of biochemical components present in the plant. The rats which was fasted for 24 hours was orally administered with distilled water and Omeprazole (20 mg/kg). 100 mg/kg each of Methanol, Ethylacetate and N-hexane fractions were administered respectively. After an hour, 1 mL /kg of 96 % ethanol was administered orally to all the rats. Omeprazole (20 mg/kg) was used as a positive control. The antiulcer activity was assessed by determining and comparing the ulcer index in the test group with that of the standard drug treated group. From the result, the effects.....

Key Words: Combretum obanense, Phytochemistry,Omeprazole,Antiulcer.

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Abstract: The use of Nanocrystalline Nickel sulphide (NiS) as a catalyst in a Hydrochloric Acid solution at 80-900C to synthesise amines A-H from nitro compounds has been developed. The current approach has the following advantages: global availability, bigger scale synthesis, higher yields, and shorter reaction times.

Key Words: Metal Sulfides; Reduction; Nickel Sulfide; Hydrochloric Acid; Nitro compounds.

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Abstract:Background: Kraft black liquor is a repository of valuable chemicals with potential application in high-value products. Fractionation of black liquor into low and high molecular weight fractions is imperative for the efficient isolation of these chemicals. Materials and Methods: This study investigated the performance of a 1KDa regenerated cellulose membrane (RCM) in the ultrafiltration of industrial hardwood kraft black liquor. The effect of pH on lignin recovery was evaluated, and resultant lignins were characterised with FTIR, DSC, TGA, Py-GC/MS and SEC. Results: The results revealed that RCM was......

Key Words: Kraft black liquor; Fractionation; Ultrafiltration; Regenerated cellulose membrane; Pulping; Lignin; Hardwood.

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Abstract: N-ethyl-3-nitro indole was prepared by treating 3-nitro indole with ethyliodide in presence of sodium hydride. N-ethyl-3-amino indole was synthesized by the reduction of N-ethyl-3-nitro indole with sodium dithionite and 0.5(N) sodium hydroxide solution in the solvent medium of ethanol at500c. N-ethyl-3-(4,4'-dinitro diphenyl amino) indole was synthesized by the reaction of N-ethyl-3-amino indole with 4-fluoro nitro benzene in presence of cesium fluoride in the solvent medium of DMSO under reflux at 1200C for 20h. N-ethyl-3-(4,4'-diamino diphenyl amino) indole was synthesized....

Key Words: N-ethyl-3-nitro indole, N-ethyl-3-amino indole, N-ethyl-3-(4,4'-dinitro diphenyl amino) indole, N-ethyl-3-(4,4'-diamino diphenyl amino) indole,6FDA, polyimide.

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Abstract: Free radical interactions with biomolecules are a process that could result in health issues like atherosclerosis, hypertension and even cancer, especially when there are insufficient antioxidants to maintain the oxidant/antioxidant balance in the body. Excessive oxidant level in the system is curbed by enzymatic and nonenzymatic antioxidants synthesized within or introduced into the system. Ascorbic acid has been, over the years, used as a standard drug for combating oxidative stress and researchers are in a continued search for a better substitute for this drug, at least one with negligible side effects. This research elucidates the antioxidant activity of 1-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl) (phenyl)methanone and its Co(II) chelate. The antioxidant property was determined....

Key Words: Free radical, antioxidant, superoxide dismutase, catalase, malondialdehyde

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Abstract: The heavy metals in soil have been a serious problem to the environment and one of the most pressings threat in the world today. The toxic heavy metals in roadside soil samples were collected randomly from three different sites for a period of four weeks between the months of June to October, 2021 and were taken through the digestion method, cooled and filtered. The filtrate was quantified using inductively coupled plasma optical emission spectrophotometry (ICP-OES). The pH ranged between 7.07 – 7.20 with soil sample recording the highest value of 7.20 with Lagos state university roadside soil while the percent moisture content value of the sample ranged from 10.7 % - 11.93 % for isheri and Iyana iba. The high moisture in Iyana-Iba area could be attributed to the reconstruction work going on along the Badagry expressway. The heavy metals (Zn, Ca, Fe, K, Na, Mg, Si) present in soil samples.......

Keywords: Soil, heavy metals, digestion, inductively coupled plasma spectrophotometry (ICP-OES) Ip address-197.211.61.41 Environmental & Analytical Toxicology

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Abstract: This article represents a study for fly ash (FA) features in NTPC, India. 14 Samples of FA were gathered from some different Indian power plants. Mostly all samples are categorized as F-class FA with high-quality pozzolanic property reported by standard. All samples were studied for their physio-chemical properties. Experiment was done by making various mortars and adhesive containing FA as substitute of cement in accord with three techniques. The constricting potency results were related with control samples prepared from OPC to get strength activity index (SAI). Mortar samples were made from each FA sample as per ASTM C 311. Their potential activity was studied at 7, 28 days. The data indicated that both physio-chemical characteristic of FA control mechanical characteristic of mortars containing FA.

Keywords: fly ash, F-class, OPC, SAI, Mortar.

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