Volume-15 ~ Issue-5 ~ May 2022

Abstract: Harungana madagascariensis is a plant used in the traditional medicine in Africa. Many studies show that it can be used for the treatment of many deseases : diarrhea, diabete,malaria, grounds, hypertension,…etc. The objective of this studiy consists to release phyotochemical screening and evaluation of polyphenols and flavonoids content of the ethanolic extract of his trunk bark. Phytochemical analysis revealed the abundance of alkaloids, polyphenols, flavonoids and tannins. Saponins, terpenoids and reducing compounds are present. However, sterols and coumarins are absent. The total polyphenols (Folin-Ciocalteu method) and total flavonoids (AlCl3 method) content was respectively 584.07±6.89 mg GAE/100g of dry matter and 146±6.76mg QE/100g of dry matter. These results showed a hight content in phenolics compounds in the ethanolic extract of Harungana madagascariensis trunk bark.

Keywords: Harungana madagascariensis; ethanolic extract; Phytochemical; total polyphenols; total flavonoids..

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[3]. Kengni F, Tala DS, Djimeli MN, Fodouop SPC, Kodjio N, Magnifouet HN, Gatsing D. In vitro antimicrobial activity of Harungana madagascariensis and Euphorbia prostrate extracts against some pathogenic Salmonella. International Journal of Biological and Chemistry Sciences. 2013. 7(3):1106-1118.
[4]. Mba JR, Weyepe FCL, Mokale ALK, Tchamgoue AD, Tchokouaha LRY, Nole T, Tarkang PA, Nehemie DT, Alambert TT, Mbita M, Dongmo B, Agbor GA. Antidiarrhoeal, Antibacterial and Toxicological Evaluation of Harungana madagascariensis. Scholar Academic Journal of Biosciences. 2017. 5(3): 138-141.
[5]. Mouthé HG, Laure MTG, Gbetnkkoma BYM, Husaind H, Greene IR, Tchaleu NB, Kouama SF. Phytochemistry and pharmacology of Harungana madagascariensis: mini review. Phytochemistry Letters. 2020. 35: 103-112

Abstract: In our ongoing research on some novel hemicyanines scaffolds a series of novel 6-substituted -2,3 dimethyl- 4- quinazolinones were prepared from o-anthranilic acid derivatives as starting material. 6- substituted -2,3 dimethyl quinazolinonium salts are valuable intermediates in the preparation of a wide range of cyanines & hemicyanines having significant absorptiophotospectrospecific potentiality and antimicrobial susceptibility. Some quinazolinonium styryl hemicyanines were synthesised by the catalytic condensation of 4- dimethylamino benzaldehyde & 4- dimethylaminonaphthaldehyde with 6- substituted, 2- methyl quinazolinonium methiodide. These QSH were synthesised with a view to study the effect of electron donor & electron withdrawing substituents at 6- position of quinazolinonium.......

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Abstract: The symmetrical compound 4-chloro-2,6-bis(4,5-diphenyl-1H-imidazol-2-yl)phenol (I) was synthetized from the rection of benzil with 2,6-diformyl-4-chlorophenol in presence of ammonium acetate and glacial acetic acid. After isolation, one arm of the compound was monoprotonated with nitric acid to yield the nitrate salt (II). The compounds were characterized by physico-chemical analyses, elemental analysis and FTIR spectroscopy. The structure of the compound II was determined by single-crystal X-ray diffraction study. The nitrate salt crystallizes in the monoclinic space group P21/c with the following unit cell parameters: a = 14.682 (5) Å, b = 14.514 (5) Å, c = 18.460 (5) Å,  = 128.210 (5)°, V = 3090.9 (17) Å3, Z = 4, R1 = 0.071 and wR2 = 0.203. The dihedral angle between the mean......

Keywords: Benzil, 2,6-diformyl-4-chlorophenol, Ammonium acetate, Spectroscopies, X-ray.

[1]. Lefebvre C.; Fortier L.; Hoffmann N. Photochemical rearrangements in heterocyclic chemistry. European Journal of Organic Chemistry. 2020, 2020(10), 1393–1404. https://doi.org/10.1002/ejoc.201901190.
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Abstract: Water, the elixir of life, is a priceless commodity and should be available to each and every person on this planet. Jaipur district is the fastest developing city of Rajasthan. Though Jaipur is famous for its historical places and art ,city is facing current trends of urbanization, over-exploitation of resources and exorbitantly increasing population. Therefore, study of physico-chemical parameters of water is considered as an important aspect of pollution studies in the environment.This study is aimed to explore the physico- chemical parameters of water quality standards of Well of RIICO at leather complex, Jaipur.

Keywords: Water quality of Well of RIICO at leather complex, Jaipur., Physico-chemical parameters, statistical analysis SAR, CAI, %Na, KR and LSI

[1]. APHA (1989), Standard methods for the examination of water and waste water, 17th Ed.American Public Health Association, American Water Works Association, Water Pollution Control Federation, Washington D.C.
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[3]. Doneen L.D. (1964), Notes on water quality in agriculture Published as a water science and engineering paper 4001, Department of water Science and engineering, University of California.
[4]. Indian Council of Medical Research (ICMR), New Delhi, India
[5]. Indian standard specification for drinking water. IS:10500, Ind. Standard Institute, India, ISI, 1983.

Abstract: Water, the elixir of life, is a priceless commodity and should be available to each and every person on this planet. Jaipur district is the fastest developing city of Rajasthan. Though Jaipur is famous for its historical places and art ,city is facing current trends of urbanization, over-exploitation of resources and exorbitantly increasing population. Therefore, study of physico-chemical parameters of water is considered as an important aspect of pollution studies in the environment.This study is aimed to explore the physico- chemical parameters of water quality standards of Newta dam Jaipur, Rajasthan

Keywords: Water quality of Newta dam, Jaipur., Physico-chemical parameters, statistical analysis SAR, CAI, %Na, KR and LSI

[1]. APHA (1989), Standard methods for the examination of water and waste water, 17th Ed.American Public Health Association, American Water Works Association, Water Pollution Control Federation, Washington D.C.
[2]. Alagbe SA (2006) Preliminary evaluation of hydrochemistry of the Kalambain Formation, Sokoto Basin, Nigeria. Environ Geol 51:39–45. |
[3]. Doneen L.D. (1964), Notes on water quality in agriculture Published as a water science and engineering paper 4001, Department of water Science and engineering, University of California.
[4]. Indian Council of Medical Research (ICMR), New Delhi, India
[5]. Indian standard specification for drinking water. IS:10500, Ind. Standard Institute, India, ISI, 1983.

Abstract: The chemical activity, adsorption, dissolution, and bioavailability of a drug may depend on the surface of the molecule. To develop new and better molecules with improved qualities of drugs, knowledge of surface tension is of most importance. In this study different molecular models have been used to describes surface tension of phenols derivatives as anti-leukaemia agents. To developing the models for surface tension of phenol derivatives we used descriptors like Mor04m, Mor23m, FDI, RDF045m, MATS5p, R3e, eHOMO, eLUMO RDF045m, MATS5p, R3e and the best model proposed for surface tension. for this we used several statistical parameters like R, PRESS, R2cv, SSY, SPRESS, PSE, LSE, PE etc. to validate the model.

Keywords: QSAR, Surface Tension, Molecular descriptors, 3D MoRSE descriptors, FDI descriptors, RDF descriptors, Moreau autocorrelation descriptors, correlation coefficient

[1]. Azarbayjani A. F., Jouyban A,, Yung C. S., Impact of Surface Tension in Pharmaceutical Sciences, J Pharm Pharmaceut Sci, 12(2), 218-228, (2009)
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Abstract: The effective control against vector borne diseases through larva source management requires the information on the breeding sites and the chemical parameters that affect larval tolerance to larvicides. This study aims to establish the correlation between the presence of chemical parameters in breeding sites of Culex quinquefasciatus and the larva tolerance to larvicides. The study was carried out in November 2021 during the small rainy season to collect information about the visual characteristics of Culex quinquefasciatus breeding sites present in Dogbo district. Then, the measurements of chemical parameters in breeding sites were done in laboratory using a spectrophotometer DR6000. The results showed that different Culex quinquefasciatus breeding sites were found.....

Keywords: chemical parameters, Culex quinquefasciatus, larval tolerance, larval habitat, Benin

[1]. Brasil. Guia de vigilância do Culex quinquefasciatus. Ministério da Saúde, Secretaria de Vigilância em Saúde, Departamento de Vigilância Epidemiológica, Coordenação Francisco Anilton Alves Araújo, Marcelo Santalucia. 3rd ed. Brasília: Ministério da Saúde. 2011.
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Abstract: Carcinus maenas (Crab) are important constituent of the human diet. Carcinus Maenas are rich source of vitamins, minerals, fibre, protein, lipid, energy and moisture. Crabs are commonly eaten and the area where the Mairua Dam is found is associated with farming activities and agro-allied industries (potential source of water contamination). The study is aimed at determining trace metals levels in Carcinus Maenas found in Mairua Dam. The study also obtained and compared results for both male and female Carcinus Maenas. From the obtained results; the concentration of Zinc (4.814 mg/L for male and 2.023 mg/L female) and Cadmium.....

Keywords: Carcinus maenas, Mairua Dam, Cadmium, Lead, Proximate, Trace metals, Zinc

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Abstract: Plants are used for treatment of number of diseases for thousands of years. Plants contain number of active compounds, which are responsible for various biological activities and play an important role in conventional as well as western medicine. It is also reported that phytochemicals, which are known as secondary metabolite from plants act as synergists or potentiators of antibacterial agents. This study has been done to find out the chemicals suitable for maximum extraction of the biologically active constituents as well as to find the effect of storage for one year on the chemical contents of seeds of Psoralea corylifolia Linn. There was a decrease in the total alkaloid and phenolic content of the seeds. The fresh seed extract has more alkaloid content than the seeds stored for a year. Also the maximum......

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