ABSTRACT: Background: This study aimed to evaluate the effects of cadmium on reproductive parameters and oxidative stress in male guinea pig (Cavia porcellus).
Materials and methods: Thirty two (32) male guinea pigs were randomly assigned to four groups of eight each. Group 1 received distilled water orally; groups 2, 3 and 4 were treated with cadmium chloride at doses 8.75, 13.13 and 26.25 mg/kg.b.w. respectively. After 90 days of treatment, all animals were sacrificed and data collected.
Result: Results revealed a significant (p < 0.05) increase of kidney and liver weights in cadmium chloride-treated animals compared to the control....
Keywords: cadmium chloride, heavy metals, male guinea pigs, oxidative stress, reproduction
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