Series-1 (Jul. – Aug. 2024) Jul. – Aug. 2024 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Progress In The Classification, Bacterial Flora And Main Flavor Substances Of Fermented Bean Curd |
| Country | : | China |
| Authors | : | Shuangying Jia || Feng Ji || Xinyu Shi || Mengying Li || Yingjie Mei || Yueqin Xue || Xinhe Zhao |
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: | 10.9790/ 264X-1004010109  |
Abstract: Fermented bean curd is a traditional Chinese fermented food, usually used as an appetizer, side dish, or condiment. During fermentation, compounds such as soybean proteins and fats are hydrolyzed by microbial action to form flavor substances. At the same time, microorganisms are also essential for the food safety of fermented bean curd. In order to comprehensively understand the characteristics and research progress of fermented bean....
Keywords: fermented bean curd; classification; fermentation strains; flavor substances
[1] Tziva M, Negro S O, Kalfagianni A, Et Al. Understanding The Protein Transition: The Rise Of Plant-Based Meat Substitutes[J]. Environmental Innovation And Societal Transitions, 2020, 35: 217-231.
[2] Wei G, Chitrakar B, Regenstein J M, Et Al. Microbiology, Flavor Formation, And Bioactivity Of Fermented Soybean Curd (Furu): A Review[J]. Food Research International, 2023, 163: 112183.
[3] Hwan C H, Chou C C. Volatile Components Of The Chinese Fermented Soya Bean Curd As Affected By The Addition Of Ethanol In Ageing Solution[J]. Journal Of The Science Of Food And Agriculture, 1999, 79(2): 243-248.
[4] Lin Q, Sirisansaneeyakul S, Wang Q, Et Al. Yunnan Fermented Bean Curds: Furu (Lufu)[J]. Modernization Of Traditional Food Processes And Products, 2016: 125-144.
[5] Li Y Y, Yu R C, Chou C C. Some Biochemical And Physical Changes During The Preparation Of The Enzyme-Ripening Sufu, A.
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| Paper Type | : | Research Paper |
| Title | : | Assessment Of Genotoxicity And Chromosomal Stability Of Aloe Extract Complex Using An In Vitro Test |
| Country | : | Korea |
| Authors | : | Dongmyong Kim || Chaeyun Yang || Yeojin Lee || Seohyeon Hwang || Hyung-Kon Lee || Yong-Seong Kwon || Yeon-Mea Choi |
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: | 10.9790/ 264X-1004011019 |
Abstract: Aloe has long been valued for its medicinal properties, particularly its anti-inflammatory, antioxidant, and immunomodulatory effects. Despite its widespread application in cosmetics, dietary supplements, and pharmaceuticals, concerns regarding the genetic stability of aloe extract components require thorough scientific evaluation. This study aimed to investigate the genotoxic potential of a complex aloe extract containing quercetin and aloesin. Utilizing the reverse mutation test on specific bacterial strains (Salmonella typhimurium and Escherichia coli) and the chromosomal aberration test on Chinese hamster lung fibroblasts (CHL/IU cells), we assessed...
Keywords: Aloe extract, Genotoxcity, chromosomal stabiliy, mutagenicity,safety
[1].
Sánchez, Marta ; González-Burgos, Elena ; Iglesias, Irene ; Gómez-Serranillos, M. Pilar, Pharmacological Update Properties Of Aloe Vera And Its Major Active Constituents, Molecules (Basel, Switzerland), 2020-03, Vol.25 (6), P.1324, Article 1324
[2].
Darzi, Saeedeh ; Paul, Kallyanashis ; Leitan, Shanilka ; Werkmeister, Jerome A. ;
Mukherjee, Shayanti, Immunobiology And Application Of Aloe Vera‐Based Scaffolds In Tissue Engineering, International Journal Of Molecular Sciences, 2021-02, Vol.22 (4), P.1-19, Article 1708
[3].
Mariana Chelu , Adina Magdalena Musuc , Monica Popa And Jose Calderon Moreno, Aloe Vera-Based Hydrogels For Wound Healing: Properties And Therapeutic Effects, Gels 2023, 9(7), 539
[4].
Kloosterman, Wigard P. ; Hochstenbach, Ron, Deciphering The Pathogenic Consequences Of Chromosomal Aberrations In Human Genetic Disease, Molecular Cytogenetics, 2014-12, Vol.7 (1), P.100-100, Article 100
[5].
Yakkala, Lakshmi Madhuri ; Somanjeri, Nithya ; Begum, Shaheen, A Validated Stability-Indicating Rp-Hplc Method For The Simultaneous Estimation Of Aloe Emodin, Aloin, And Emodin In A Marketed Formulation Of Aloe Vera, Journal Of Analytical Chemistry (New York, N.Y.), 2024, Vol.79 (6), P.808-812
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| Paper Type | : | Research Paper |
| Title | : | CRISPR-Cas9 In Cancer Therapy: Applications, Challenges, And Future Directions |
| Country | : | Canada |
| Authors | : | Jahnavi Dalmia |
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: | 10.9790/ 264X-1004012031 |
Abstract: CRISPR-Cas9 technology provides novel and revolutionary strategies for cancer therapy through accurate genome editing to target the intervention in malignancies. Here, we review the wide varieties of applications for CRISPR/Cas9 in cancer to disrupt oncogenes with clear examples and thorough discussion on improving immunotherapies as well as presenting more advanced modeling systems using CRISPR allowing new personalized....
Keywords: CRISPR-Cas9, Drug resistance, Cancer therapy, Genome editing, Immunotherapy.
[1] Katti, A.; Diaz, B.J.; Caragine, C.M.; Sanjana, N.E.; Dow, L.E. Crispr In Cancer Biology And Therapy. Nat. Rev. Cancer 2022, 22, 259–279.
[2] Feng, J.; Lu, H.; Ma, W.; Tian, W.; Lu, Z.; Yang, H.; Cai, Y.; Cai, P.; Sun, Y.; Zhou, Z.; Et Al. Genome-Wide Crispr Screen Identifies Synthetic Lethality Between Dock1 Inhibition And Metformin In Liver Cancer. Protein Cell 2022, 13, 825–841.
[3] Zou, Y.; Zheng, S.; Xie, X.; Ye, F.; Hu, X.; Tian, Z.; Yan, S.M.; Yang, L.; Kong, Y.; Tang, Y.; Et Al. N6-Methyladenosine Regulated Fgfr4 Attenuates Ferroptotic Cell Death In Recalcitrant Her2-Positive Breast Cancer. Nat. Commun. 2022, 13, 2672.
[4] Wan, C.; Mahara, S.; Sun, C.; Doan, A.; Chua, H.K.; Xu, D.; Bian, J.; Li, Y.; Zhu, D.; Sooraj, D.; Et Al. Genome-Scale Crispr-Cas9 Screen Of Wnt/Β-Catenin Signaling Identifies Therapeutic Targets For Colorectal Cancer. Sci. Adv. 2021, 7, Eabf2567.
[5] Pan, J.; Zhang, M.; Dong, L.; Ji, S.; Zhang, J.; Zhang, S.; Lin, Y.; Wang, X.; Ding, Z.; Qiu, S.; Et Al. Genome-Scale Crispr Screen Identifies Laptm5 Driving Lenvatinib Resistance In Hepatocellular Carcinoma. Autophagy 2023, 19, 1184–1198
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| Paper Type | : | Research Paper |
| Title | : | Utilization Of Plant Extractives And Compounds For Sitophilus Oryzae (Rice Weevil) Management |
| Country | : | Kenya |
| Authors | : | Sylvia Awino Opiyo |
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: | 10.9790/ 264X-1004013241 |
Abstract: In stored crops, Sitophilus oryzae (rice weevil) can cause damage of up to 80%, depending on the circumstances of storage. A vast variety of grains and seeds, including sorghum, wheat, corn, oats, rye, barley, rice, and beans, are all highly palatable to the bug. The most practical and effective technique to control insect pests in stored food products is to use synthetic insecticides. These substances do, however, have adverse effects on the ecosystem. It has been established that plants contain important compounds that are poisonous to insects. Because they are renewable, do not persist in the environment, and are generally safe for use by humans, non-target creatures, and natural enemies, botanicals are the preferred method of controlling pests and diseases.......
Keywords: Rice weevil; Sitophilus oryzae; stored grains; Insecticide; plant extracts; plant compounds.
[1]
Park D. S., Peterson C., Zhao S., Coats J. (2004). Fumigation Toxicity Of Volatile Natural And Synthetic Cyanohydrins To Stored-Product Pests And Activity As Soil Fumigants. Pest Manag Sci. 60: 833-838.
[2]
Campbell J. (2009). Fitness Consequences Of Multiple Mating On Female Sitophilus Oryzae L. (Coleoptera: Curculionidae). Environ Entomol. 34: 833-843.
[3]
Huang F., Subramanyam B. (2005). Management Of Five Stored-Product Insects In Wheat With Pirimiphos-Methyl And Pirimiphos-Methyl Plus Synergized Pyrethrins. Pest Manag Sci. 61: 356-362.
[4]
Isman M. (2006). Botanical Insecticides, Deterrents, And Repellents In Modern Agriculture And An Increasingly Regulated World. Annu Rev Entomol. 51: 45-66.
[5]
Opiyo S.A. (2021). A Review Of Insecticidal Plant Extracts And Compounds For Stored Maize Protection. Iosr J Appl Chem. 14(10): 23-37.
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| Paper Type | : | Research Paper |
| Title | : | Unraveling Hypothyroidism: The Genetic Predisposition And Molecular Basics |
| Country | : | |
| Authors | : | Rana Rahimova || Sabina Gulieva || Fakhranda Rzaeva || Ellada Huseynova || Firangiz Gulieva |
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: | 10.9790/ 264X-1004014244 |
Abstract: Hypothyroidism, a prevalent endocrine disorder affecting millions globally, manifests due to insufficient thyroid hormone production. While environmental factors undoubtedly contribute, recent advancements in genetic and molecular research have illuminated the complex interplay between genetic predisposition and molecular mechanisms. Among the key players, pendrin, an iodide transporter in thyroid follicular cells, and iodothyronine deiodinases (DIOs) stand out, shedding light on the intricate pathophysiology of hypothyroidism. In this article, we delve into the genetic underpinnings of hypothyroidism, explore the multifaceted role of pendrin, and unravel the significance of iodothyronine deiodinases, supported by contemporary research evidence.
[1]
Vijay Panicker, (2011). Genetics Of Thyroid Function And Disease. Clin Biochem Rev. Nov; 32(4): 165–175.
[2] Christine E. Cherella And Ari J. Wassner, (2017), Congenital Hypothyroidism: Insights Into Pathogenesis And Treatment, Int J Pediatr Endocrinol.; 11. Doi: 10.1186/S13633-017-0051-0
[3] Naoya Yamaguchi, Atsushi Suzuki, Aya Yoshida Et All. (2022), The Iodide Transporter Slc26a7 Impacts Thyroid Function More Strongly Than Slc26a4 In Mice, Sci Rep. 12: 11259 Doi: 10.1038/S41598-022-15151-4
[4] Joaquin Lado Abeal, (2008), Pendred Syndrome, Expert Rev Endocrinol Metab, 3(5):635-643. Doi: 10.1586/17446651.3.5.635.
[5] Liuska Pesce, Aigerim Bizhanova, Juan Carlos Caraballo Et All., (2012), Tsh Regulates Pendrin Membrane Abundance And Enhances Iodide Efflux In Thyroid Cells, Endocrinology. 153(1): 512–521. Doi: 10.1210/En.2011-1548.
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| Paper Type | : | Research Paper |
| Title | : | Effect Of Aqueous Leaf Extract Of Nauclea Latifolia On Antioxidant And Lipid Biomarkers Of Potassium Bromate - Induced Albino Rats |
| Country | : | Nigeria |
| Authors | : | Victor Nnaemeka Ogbonna || Victor Samuel || Otuamiobhedio Messiah Wilfred || Victoria Okure || Vincent Obinna Awah |
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: | 10.9790/ 264X-1004014551 |
Abstract: The current study evaluated the effect of aqueous leaf extract of Nauclea latifolia on antioxidant and lipid biomarkers of potassium bromate induced albino rats. A total of twenty-five (25) apparently assumed healthy male Albino rats were procured, they were divided into five (5) groups and five (5) animals in each cage according to their weight. on the Effect of aqueous leaf extract of Nauclea latifolia on Lipid Biomarkers of Potassium bromate induced....
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