iosr-JDMS   Volume-15 ~ Issue-12 ~ December-2016

Abstract: Background: The purpose of this study was to evaluate the condylar changes through cone beam computed tomography images in patients treated with twin block functional appliance. Material and Method: In this study, CBCT of 30 patients who were treated with the Twin Block appliance were used. Pretreatment(TO) and Posttreatment (T1) condylar volume was compared on the 3D images. Angular measurements (Saddle angle, Gonial angle, ANB angle, Angle of Convexity and lower facial Height angle) and Linear Measurements (Na-Me, Co-Gn,CoR-CoL, CC-Gn) were also measure and compared by using 3D images. Differences between T0 and T1 were analyzed and compared with the use of paired 't' test and Wilcoxon signed rank test..........

Keywords:Cone Beam Computed Tomography,Functional Appliance,Twin Block, Condyle, Temporomandibular Joint

[1]. Little AC, Jones BC, DeBruine LM. Facial attractiveness: evolutionary based research. Philosophical Transactions of the Royal
Society B: Biological Sciences. 2011 Jun 12;366(1571):1638-59.
[2]. MCNAMARA JR JA. Components of Class II malocclusion in children 8-10 years of age. The Angle orthodontist. 1981
Jul;51(3):177-202.
[3]. Tümer N, Gültan AS. Comparison of the effects of monoblock and twin-block appliances on the skeletal and dentoalveolar
structures. American journal of orthodontics and dentofacial orthopedics. 1999 Oct 31;116(4):460-8.
[4]. Schaefer AT, McNamara JA, Franchi L, Baccetti T. A cephalometric comparison of treatment with the Twin-block and stainless
steel crown Herbst appliances followed by fixed appliance therapy. American journal of orthodontics and dentofacial orthopedics.
2004 Jul 31;126(1):7-15.
[5]. Cozza P, Baccetti T, Franchi L, De Toffol L, McNamara JA. Mandibular changes produced by functional appliances in Class II
malocclusion: a systematic review. American Journal of Orthodontics and Dentofacial Orthopedics. 2006 May 31;129(5):599-e1.

Abstract:Objective: To describe outcome of patients with relapsed Clear cell sarcoma when treated with Temazolamide. Methods: 36 year gentle man a diagnosed case of clear cell sarcoma of foot post wide local excision was being treated with adjuvant RT. On regular follow up patient had multiple time regional recurrence along with distant metastasis for which he received Temazolamide and had partial remission. Result: With regional therapy (surgical) and systemic chemotherapy in form of temazolamide such aggressive tumour can be managed and patient can achieve long term survival..........

Keywords: temazolamide , clear cell sarcoma .

[1]. Liu X, Zhang H, Dong Y: Primary clear cell sarcoma of humerus: case report.

[2]. World J SurgOncol 2011, 9:163.

[3]. Sandberg AA, Bridge JA: Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: clear cell sarcoma (malignant melanoma of soft parts).

[4]. Cancer Genet Cytogenet 2001, 130:1-7.

[5]. Enzinger FM: Clear-cell sarcoma of tendons and aponeuroses. An analysis of 21 cases..

Abstract: Background: The thalassemia syndromes are a heterogeneous group of inherited disorders caused by genetic lesions leading to decreased synthesis of one or more of the globin subunits. The β-thalassemia major is the most severe form and the affected children are dependent on regular blood transfusions for survival. One of the major complications in chronically transfused patients is development of irregular antibodies and in this situation; further transfusion of compatible red cell is difficult..........

Keywords:Alloimmunization, Irregular antibodies, Thallassemia, Transfusion

[1]. John NL. The thalassemias and related disorders: Quantitative disorders of hemoglobin synthesis; Wintrobe's Clinical Hematology,
tenth edition, Vol. I, chapter 1999 53:1405–1448.
[2]. Collins AF, Goncalves Dias C, Haddad S et al Comparison of a transfusion preparation of newly formed red cells and standard
washed red cell transfusion in patients with homozygous beta Thalassemia. Transfusion (1994) 34:517–520
[3]. Thuret I Therapeutic management of patients with thalassemia major. Bull Soc Pathol Exot (2000) 94:95–97

[4]. Weiner M, Kartpatkin M, Hart D et al Cooley's anemia: High transfusion regimen and chelation therapy. Results and prospective. J
Paediatr (1978) 92:653–658
[5]. Proter JB Practical management of iron overload. Curr Opin Hematol (1997) 4:436–441

Abstract: Early detection of breast cancer can provide patients a wider range of therapeutic options as well as a higher success rate of therapy that lowers mortality. Metastatic breast cancer is the principal cause of breast cancer death worldwide. Change in serum levels of some biochemical parameters could assist diagnosis, prediction and follow-up of metastatic breast cancer. Total 235 human subjects were taken in the study...........

Keywords: Alkaline phosphatase, Acid phosphatase, Breast cancer, Calcium.

[1]. Weigelt B, Peterse LJ and Laura JV. Breast cancer metastasis: markers and models. Nature reviews cancer.2005; 5:591-602.
[2]. Feller L, Kramer B and Lemmer J.A short account of metastatic bone disease. Cancer Cell Int.2011;11: 24–9 .
[3]. Korde LA and Gralow JR Can we predict who's at risk for developing bone metastases in breast cancer? J Clin Oncol .2011; 29:3600–4.
[4]. Cho SY, Choi HY. Causes of death and metastatic patterns in patients with mammary cancer. Am J Clin Pathol.1980; 73:232-4.
[5]. Halabay R, Abdollahi J, Martinez ML. Acid phosphatase in human breast tumors. Breast Cancer Res. 2001; 3: E002..

Abstract: Cleidocranial dysplasia (CCD) is an autosomal dominant disease characterized by general dysplastic bone formation manifested in typical malformations in the skull, the pelvis and the thoracic region. It is caused by mutation in the gene on 6p21 encoding transcription factor Core Binding Factor Subunit Alpha 1 (CBFA1) or Runt related transcription factor 2 (RUNX2), which is involved in the differentiation of osteoblasts and bone formation. This paper reports a case of cleidocranial dysplasia in a 28 year old female patient and review of literature with a brief emphasis on the role of CBFA1 gene in the pathogenesis of CCD. Radiographs of the skull, teeth and clavicles were the diagnostic evidences of our case.........

Keywords: CBFA gene; Clavicle; Cleidocranial Dysplasia; Supernumerary Teeth; Open fontanelle.

[1]. Ilan Golan, Uwe Baumert, Paul Held, Stefan Feuerbach, Dieter Mubig. Radiological Findings and Molecular Genetic Confirmation
of Cleidocranial Dysplasia. Clinical Radiology, 2002; 57(6): 525-9.
[2]. Manjunath K, Kavitha B, Saraswathi TR, Sivapathasundharam B, Manikandhan R. Cementum analysis in cleidocranial dysostosis.
Indian Journal of Dental Research. 2008; 19(3): 523-6.
[3]. McNamara CM, O' Riordan BC, Blake M, Sandy JR. Cleidocranial dysplasia: radiological appearances on dental panoramic
radiography. Dentomaxillofacial Radiology. 1999; 28: 89-97.
[4]. Mohan RPS, Suma GN, Vashishth S, Goel S. Cleidocranial dysplasia: clinico-radiological illustration of a rare case. Journal of Oral
Science. 2010; 52(1):161-166.
[5]. Londono RM, Lee B: University of Washington, Seattle. Cleidocranial Dysplasia-Gene Reviews, NCBI Bookshelf [Internet]. [Cited
2006 Jan 3]..

Abstract: Background: The locking compression plate (LCP) with combination holes is a newer device in fracture fixation. We undertook a study comparing the LCP with limited contact dynamic compression plate (LC-DCP) in the treatment of diaphyseal fractures of both bones of the forearm. Materials and Methods: This is a prospective comparative study, 36 patients (18 in each group) with fractures of both the forearm bones (72 fractures) were treated with one of the two devices. The average age of the patients was 30.5 years (range 16-60 years) with mean followup of 2.1 years (range 1.5-2.8 years)..........

Keywords: Diaphyseal forearm fractures, limited contact dynamic compression plate, locking compression plate, plate fixation, radius and ulna

1]. Knight RA, Purvis GD. Fractures of both bone forearm in Adults. J Bone Joint Surg Am 1949;31:755-64.
[2]. Leung F, Chow SP. Locking compression plate in the treatment of forearm fractures: A prospective study. J Orthop Surg (Hong Kong) 2006;14:291-4.
[3]. Anderson LD, Sisk D, Tooms RE, Park WI 3rd. Compression-plate fixation in acute diaphyseal fractures of the radius and the ulna. J Bone Joint Surg Am 1975;57:287-7.
[4]. Bagby GW, James JM. The effect of compression on the rate of Fracture healing using a special plate. Am J Surg 1958;95:761-71.
[5]. Müller ME, Allgöwer M, Willenegger H. Technique of internal fixation of fractures. NewYork, Springer; 1965

Abstract: Primary angiosarcoma is a rare malignant tumour that arise from endothelial cells lining the vascular channels.It is an aggressive tumour with a high propensity for metastasis. Primary angiosarcomas account for <1% of all breast cancer cases . The other more frequent histological subtypes encountered are malignant fibrous histiocytoma, fibrosarcoma and liposarcoma.1 Most angiosarcomas are secondary to radiotherapy treatments for breast cancer or to an arm lymphoedema subsequent to a modified radical mastectomy.

Keywords: Primary,angiosarcoma,malignant, endothelial,vascular ,lymphoedema

[1]. S. A. Vorburger, Y. Xing, K. K. Hunt et al., ―Angiosarcoma of the breast,‖ Cancer, vol. 104, no. 12, pp. 2682–2688, 2005.
[2]. X. Y. Wang, J. Jakowski, O. W. Tawfik, P. A. Thomas, and F. Fan, ―Angiosarcoma of the breast: a clinicopathologic analysis of
cases from the last 10 years,‖ Annals of Diagnostic Pathology, vol. 13, no. 3, pp. 147–150, 2009.
[3]. J. S. Scow, C. A. Reynolds, A. C. Degnim, I. A. Petersen, J. W. Jakub, and J. C. Boughey, ―Primary and secondary angiosarcoma of
the breast: the Mayo Clinic experience,‖ Journal of Surgical Oncology, vol. 101, no. 5, pp. 401–407, 2010.
[4]. M. Ohta, Y. Tokuda, S. Kuge et al., ―A case of angiosarcoma of the breast,‖ Japanese Journal of Clinical Oncology, vol. 27, no. 2,
pp. 91–94, 1997.
[5]. T. Sher, B. T. Hennessy, V. Valero et al., ―Primary angiosarcomas of the breast,‖ Cancer, vol. 110, no. 1, pp. 173–178, 2007

Abstract: Background: Optimal titration of inspired oxygen is important to prevent hyperoxia in mechanically ventilated patients in ICUs, but there is paucity of data about FiO2 practice among patients in NICUs. We evaluate the association of excessive FiO2 exposure with acute lung injury in mechanically ventilated young infants. Methods: By prospective study, we enrolled NICU patients who underwent invasive mechanical ventilation. Ventilator settings (FiO2) and corresponding SpO2 were collected for the first 48 hours. Excessive FiO2 was defined as FiO2 > 0.7. The association between excessive exposure and pulmonary outcomes was analyzed by change in oxygenation index (OI) and lung injury score by correlation.........

Keywords: Acute lung injury, FiO2, Hyperoxia , Mechanical ventilation

[1]. Jindal SK. Oxygen Therapy: Important Considerations. Indian J Chest Dis Allied Sci 2008; 50: 97-107.
[2]. MacNee W. Prescription of oxygen: still problems after all these years. Am J Respir Crit Care Med 2005; 172: 517-8.
[3]. Rachmale S, LI G, Malinchoc M. Practice of excessive FiO2 and effect on pulmonary outcomes in mechanically ventilated
patients with acute lung injury. Respiratory care 2012; 51(11):1887-93.
[4]. Comroe J. Oxygen toxicity, the effect of breathing high concentration of oxygen for 24 hours in normal men at sea level and
simulated at 18,000 feet. JAMA 1945; 128(10):710-17.
[5]. MacIntyre NR. Supporting oxygenation in acute respiratory failure. Respiratory Care 2013; 58(1):142-50.

Abstract: Background: In nulliparous women dystocia is the most common obstetric problem and its etiology is largely unknown. The conventional view is that dystocia may be caused by abnormalities of either the passage, power or the passenger. In the past, the importance of passage and power has been highlighted, but the role of passenger (the fetus) in the etiology of dystocia has received less attention. Aims and Objectives : To study the association between labor pattern and birth weightandto evaluate the impact of birth weight on maternal and neonatal outcome..........

Keywords: Birth weight, laborpatterns, perinatal outcome

[1]. Al-Wazzan RM, Sarsam SD. Fetal macrosomia: Maternal and Perinatal outcome. Al - Kindy Col Med J 2011; 7: 50-55.
[2]. Boulet SL, Alexander GR, Salihu HM, Pass MA. Macrosomic births in the United States: Determinants, outcomes and proposed grades of risk.Am J ObstetGynecol 2003; 188: 1372-8.
[3]. Gurel SA, Gurel H, Sener T, Hassa H, Ozalp S. The Large for Gesational Age infant: a study of labour, delivery and newborn characteristics. Eastern Journal of Medicine 1996; 1:10-13.
[4]. Elvander C, Hogberg U, Ekeus C. The influence of fetal head circumference on labor outcome: a population-based register study. ActaObstetGynecolScand 2012; 91(4): 470-5.
[5]. Turner MJ, Rasmussen MJ, Turner JE, Boylan PC, MacDonald D, Stronge JM. The influence of birth weight on labor in nulliparas. ObstetGynecol 1990; 76: 159-63.

Abstract: Background And Objectives: Tuberculosis (TB) is disease caused by Mycobacterium tuberculosis, and rarely by other "tuberculosis complex". It is the number one killer infectious disease in developing countries. World Health Organization (WHO) reported in 1990 tuberculosis as a Global Burden of Disease and seventh most common morbidity-causing disease in the world, and expected to be the same position up to 2020. It is one of the oldest diseases known to affect humans. It is a major health problem in India.........

Keywords: Pulmonary Tuberculosis, smear positive, AFB(Acid Fast Bacilli)

[1]. Technical and Operational Guidelines for Tuberculosis Control. 1st ed. 2005.
[2]. Kapur V, Whittam T, Musser J. Is Mycobacterium tuberculosis 15000 years old? J Infect Dis.1994; 170:1348-9.
[3]. Hayman j. Mycobacterium ulcerans: an infection from Jurassic time? Lancet. 1984; 2:1015-6.
[4]. Central TB Division (CTD): Directorate General Of Health Services, Ministry Of Health And Family Welfare, Government Of India. RNTCP Status Report. 1st ed. 2011. Print. [5]. India, Ministry. "Technical And Operational Guidelines For TB Control In India 2016 :: Central TB Division". Tbcindia.gov.in. N.p., 2016. Web. 22 Nov. 2016

Abstract: The aim of this study was to evaluate and compare microwave disinfection with ultraviolet light disinfection of dental gypsum casts.Materials and methods : A total of 60 blocks were prepared from an L- key mold using Type III dental stone. Of the 60 blocks, 30 blocks were contaminated with 1 ml suspension of Staphylococcus aureus and 30 blocks were contaminated with 1 ml suspension of Pseudomonas aeruginosa. Then, the blocks were disinfected with microwave irradiation using the microwave oven and UV light disinfection. Bacteriologic procedures were performed.........

Keywords: Cast, disinfection ,gypsum, microwave, uv light

[1]. Leung RL, Schonfeld SE. Gypsum casts as a potential source of microbial cross-contamination. J Prosthet Dent 1983;49(2):210-1.
[2]. Mitchell DL, Hariri NM, Dunacson MG, Jacobsen NL, MacCallum RE. 1997. Quantitative Study of Bacterial Colonization of Dental Casts. The Journal of Prosthetic Dentistry, 78 (5): 518- 521
[3]. American Dental Association Council on Scientific Affairs and Council on Dental Practice. 1996. Infection Control Recommendations for the Dental Office and the Dental Laboratory. Journal of American Dental Association, 127 (5): 672- 680.
[4]. Adobo GL, Zanarotti E, Fonseca RG, Santos CAD. 1999. Effect of Disinfectant Agents on Dimensional Stability of Elastomeric Impression Materials. The Journal of Prosthetic Dentistry, 81 (5): 621- 624.
[5]. Ünalan F., Akit KS., Gürler B., Nakipoglu Y. (1994) ANKEM Derg., 8 (1), 73-782

Abstract: Background : Histopathological evaluation is a major component in the management of colorectal carcinoma. It acts as a important prognostic indicator in colorectal carcinoma resection and decides the adjuant therapy. Methods : this retrospective analysis of histopathological data of one year duration conducted on colonoscopic and surgical biopsies of colorectal lesions. Results: it shows one third of patient has rectal lesion and rest comprises entire colon, during presentation itself mostly it shows muscularis propria invasion. The commonest histopathological type being adenocarcinoma. Conclusion: colonoscopic biopsy showing muscularis propria invasion can guide us about adjuvant chemo radiation later and patient can be prepared for that

Keywords: Histopathology, colonoscopy, tumour invasion, adenocarcinoma

[1]. Tomislav D, Vassiliki LT Colon Cancer, Adenocarcinoma. Available via Medscape CME. http://www.medscape.com/viewarticle/277496. update June 2009
[2]. Bull AD, Biffin AH, Mella J, et al. Colorectal cancer pathology reporting: regional audit. J Clin Pathol. 1997;50:138–142. doi: 10.1136/jcp.50.2.138. [PMC free article][PubMed] [Cross Ref]
[3]. Beattie GC, McAdam TK, Elliott S et al (2003) Improvement in quality of colorectal cancer pathology reporting with a standardized proforma – A comparative study. Blackwell Publishing ltd, Colorectal Disease 5:558–562 [PubMed]
[4]. Quirke P, Morris E. Reporting colorectal cancer. Histopathology. 2007;50:112–130. doi: 10.1111/j.1365-2559.2006.02543.x.[PubMed] [Cross Ref]
[5]. Keating J, Lolohea S, Kenwright D. Pathological reporting of rectal cancer: national audit. NZ Med J. 2003;116:1178.[PubMed]

Abstract: Background: Ventral hernia surgical repair done using prolene mesh. Mesh can be placed over anterior rectus sheath(onlay) or pre peritoneal space. These two techniques are compared to one another. Materials and methods : Patients admitted in the surgical wards with ventral hernias at Chengalpattu Medical College Hospital for a period of one year were operated by the above mentioned two methods and five variables compared between two groups. Results: Among the 50 patients, 25 patients underwent onlay and 25 patients underwent preperiotneal mesh repair. Out of 25 cases of onlay, only 8 cases took more than one hour for operating. Out of 25 cases of preperitoneal mesh repair , hospital stay was more than five days for only.........

Keywords: Ventral hernia; onlay vs preperitoneal; mesh repair

[1]. Björk D, Cengiz Y, Weisby L, Israelsson LA. Detecting Incisional Hernia at Clinical and Radiological Examination. Surg Technol
Int., 2015; 26: 128-31.
[2]. Fortelny RH, et al. Effect of suture technique on the occurrence of incisional hernia after elective midline abdominal wall closure:
study protocol for a randomized controlled trial. Trials, 2015; 16: 52.
[3]. SSAT patient care guidelines. Patient Care Committee, Society for Surgery of the Alimentary Tract. Surgical repair of incisional
hernias. J Gastrointest Surg., 2004; 8: 369-70.
[4]. Timmermans L, de Goede B, van Dijk SM, Kleinrensink GJ, Jeekel J, Lange JF. Meta- analysis of sublay versus onlay mesh repair
in incisional hernia surgery. Am J Surg., 2014; 207: 980-8.
[5]. Rajesh Godara, Pardeep Garg, Hans Raj, Sham L Singla. Comparative evaluation of "Sublay"versus "Onlay" meshplasty in ventral
hernias. Indian Journal of Gastroenterology, 2006; 25: 222-3.

Abstract: Treatment with a combination of chemotherapy and radiotherapy is known to be associated with gastrointestinal stricture in both children and adults with malignancies. However, gastrointestinal stricture resulting from chemotherapy alone is a rare complication in paediatric malignancies. We experienced a rare case of jejunal stricture causing small bowel obstruction in a child with retinoblastoma during receiving chemotherapy.

Keywords: Jejunal stricture; Retinoblastoma; Chemotherapy

[1]. Castillo BV Jr, Kaufman L. Pediatric tumors of the eye and orbit. Pediatr Clin North Am.2003;50:149-172.
[2]. Shields CL, Shields JA. Diagnosis and management of retinoblastoma. Cancer Control.2004;11:317-327.
[3]. Honavar SG, Singh AD. Management of advanced retinoblastoma. Opthalmo Clin North Am.2005;18:65-73.
[4]. Di Fiore F, Van Cutsem E: Acute and longterm gastrointestinal consequences of chemotherapy. Best Pract Res Clin Gastroenterol
23:113-124, 2009
[5]. Beck KE, Blansfield JA, Tran KQ, et al. Enterocolitis in patients with cancer after antibody blockage of cytotoxic T-lymphocyteassociated
antigen 4. J Clin Oncol 2006;24:2283-2289

Abstract: Non fuctionning pituitary adenomas (NFPA) are glandular tumors of the pituitary gland that do not manifest in any clinical aspect related to hypersecretion. They represent 28 to 33.2% of pituitary adenomas (PA). They are diagnosed at a later stage than functional adenomas, tumor size in these tumors is often more importantwhich is responsible for visual impairment and anterior pituitary deficiency We specify in this article the phenotypic and evolutionary characteristics of NFPA in women

Keywords: Non fuctionning pituitary adenomas, mmunohistochemistry, MRI, surgery, radiotherapy

[1]. G. Raverot and al, adénome hypophysaire gonadotrope, EMC Endocrinologie nutrition 2014 ;vol 11 n3
[2]. E. Fontana and al, épidémiologie des adénomes hypophysaires, revue médicale suisse ; 2009, vol n223
[3]. Molitch M.E. Non functioning pituitary tumors and pituitary incidentalomas Endocrinol Metab Clin N Am 2008 ; 37 : 151-171
[4]. G. Raverot and al, adénome hypophysaire gonadotrope, EMC endocrinologie Nutrition, juillet 2014, vol n3 ; 1-8
[5]. G.Assic and al, exploration et prise en charge des adénomes hypophysaires non fonctionnels : exploration biologique et radiologique, consensus de la société française d'endocrinologie ; juillet 2015 ; vol 77 : 14-20

Abstract: Gardneralla vaginalis as well as Trichomonas vaginalis are among the most common vectors of vaginal discharges and urogenital infections. The objective of this work was to evaluate the prevalence of Gardnerella vaginalis-Trichomonas vaginalis Co-infection, Gardneralla vaginalis and Trichomonas vaginalis versus the contributions of some sociodomestics factors among women of reproductive age attending the Catholic's Hospital Mgr Jean Zoa of Nkolndongo, Yaounde..........

Keywords:Gardneralla vaginalis, Trichomonas vaginalis, Gardneralla vaginalis-Trichomonas vaginalis Coinfection, prevalence, sociodomestic.

[1]. R.M. Brotman, Vaginal microbiome and sexually transmitted infections: an epidemiologic perspective, J Clin Invest, 121(12), 2011,
4610-4617, doi: 10:1172/JCI571172.
[2]. J.M. Marrazzo, Interpreting the epidemiology and natural history of bacterial vaginosis: are we still confused, Anaerobe , 17(4),
2011, 186-190, doi:10.1016/j.anaerobe.2011.03.016.
[3]. C.S. Bradshaw, S.N. Tabrizi, C.K. Fairley, A.N. Rudland E. and S.M. Garland, The association of Atopobium vaginae and
Gardnerella vaginalis with bacterial vaginosis and recurrence after oral metronidazole therapy, J Infect Dis, 194(6 ), 2006, 828 - 836.
[4]. J.P. Menard, F. Fenollar, M. Henry, F. Bretelle, D. Raoult, Molecular quantification of Gardnerella vaginilis and atopobium
vaginae loads to predict bacterial vaginosis, Clin Infect Dis, 47(1), 2010, 33-43.
[5]. J.P. Menard, C. Mazouni, I.Salem-Cherif, et al., High vaginal concentrations of Atopobium vaginae and Gardnerella vaginalis in
women undergoing preterm labor, Obstet Gynecol, 115(1 ) 2010, 134-40.

Abstract: Secondary hyper parathyroidisme (SHP) is defined by a compensatory elevation of the parathormone (PTH) habitualy associated with normal or hypocalcemia. This situation is frequently in multiple pathologies. Chronic renal insufficiency and vitamine D insufficiency are the most common causes. When the diagnosis is established, additional tests are performed to rule out differential diagnoses and institute effective treatment. In fact, the absence of correction of secondary hyperparathyroidism can lead to serious complications.........

Keywords: Secondary hyper parathyroidisme, hypocalcemia, Chronic renal insufficiency, vitamine D insufficiency PTH

[1]. Hyperparathyroïdies secondaires (hors insuffisance rénale) Rose-Marie Javier .Septembre 2012 ; Vol 79 - N° 4 P. 239-243
[2]. Ganesh SK, Stack AG, Levin NW, et al. Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients. J Am Soc Nephrol 2001;12: 2 8.
[3]. J. Cunningham and al, Secondary Hyperparathyroidism: Pathogenesis, Disease Progression, and Therapeutic Options, Clin J Am Soc Nephrol,2011, 6: 913–921.
[4]. J. Cunningham and al, Secondary Hyperparathyroidism: Pathogenesis, Disease Progression, and Therapeutic Options, Clin J Am Soc Nephrol,2011, 6: 913–921.
[5]. I. Gorsane et coll, Hyperparathyroïdie secondaire compliquée de tumeurs brunes, Revue de médecine interne 36S ,2015 ; A76–A18.

Abstract: Background: Bone healing is a complex biological process, involving many cell types, thousands of genes, and extracelullar matrix organization. Many studies had been done to enhance the healing of bone fracture, including biological intervention by using natural materials that can be found in the surrounding environment. Propolis is a substance produced by honeybees which have antioxidant, antimicrobial, and anti inflammation effects. This study was conducted to evaluate the effect of propolis inLawang on the bone healing process, reflected by the number of osteoblasts, osteoclasts, and chondrocytes..............

[1]. Arroyo S, Hutete F, Jesus M, Cadiz M, Legeai L, Micol V, Segura A, Joven J, Pintor J. 2001. The Impact of Polyphenols on Chondrocyte Growthand Survival. Spain.
[2]. Turk C, Halici M, Guney A et al. 2004. Promotion of fracture healing by vitamin E in rats. J Int Med Res 32:507–512.
[3]. Xu H,Watkins BA, Seifert MF. 1995. Vitamin E stimulates trabecular bone formation and alters epiphyseal cartilage morphometry. Calcif Tissue Int 57: 293–300.
[4]. Yilmaz HR, Uz E, Yucel N, Altuntas I, Ozcelik N. 2004. Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver. J BiochemMol Toxicol 18: 234–238.
[5]. Zhu W, Murrell GA, Lin J, Gardiner EM, Diwan AD. 2002. Localization of nitric oxide synthases during fracture healing. J Bone Miner Res 17: 1470–1477.

Abstract: Context: The emergence of Multi-Drug Resistant Tuberculosis (MDR-TB), has become a significant public health problem and an obstacle to effective TB control. In India prevalence of Primary MDR-TB is 2.2% (1.9– 2.6%) and Secondary MDR-TB is 15% (11–19%).So the factors responsible for Causation and Emergence of MDR-TB need to be assessed. Aims: Investigating the factors associated with Multi Drug Resistant-Tuberculosis. Setting & Design: An Unmatched Case Control Study, Purposively Recruited 68 MDR-TB Patients as Cases from DOTs Plus Site, NCH (New Civil Hospital) Surat and 136 Non - MDR-TB Patients on DOTS Therapy from Tuberculosis Ward, NCH Surat and UHC (Urban health Centre) and PHC (Primary health Centre) from Surat District as Control..........

Keywords: Multi drug resistant tuberculosis, risk factors, case control

[1]. Libo Liang et al.Factors contributing to the high prevalence of multidrug-resistant tuberculosis: a study from China.Thorax
2012;67:632-638
[2]. Central TB Division, Directorate General of Health Services, Ministry of Health & Family, India. Guidelines for programmatic
management of Drug Resistant Tuberculosis in India 2012.
[3]. James C.M. Brust et al. High Treatment Failure and Default Rates for Patients with MDR TB in KwaZulu-Natal, South Africa,
2000–2003 Int J Tuberc Lung Dis. 2010 ; 14: 413–419.
[4]. Central TB Division, Directorate General of Health Services, Ministry of Health & Family, India. Guidelines for programmatic
management of Drug Resistant Tuberculosis in India 2010.
[5]. Skrahina A et al. Multidrug-resistant tuberculosis in Belarus: the size of the problem and associated risk factors. Bulletin World
Health Organisation. 2013 :91:36-45

Abstract: Approximately 80% of the population secrete their blood group antigens in their saliva and other body fluids while others do not. These antigens in the digestive secretions have an association with the development of the diseases of the gastrointestinal tract. In this context, we did a case control study to test if there is any association between the blood antigen secretor status and the development of various gastrointestinal diseases..........

Keywords: Blood group antigen, secretor, gastro-intestinal diseases

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Abstract: This study aimed to define the bacteriological etiology and incidence of urinary tract infections (UTIs) among 55 pregnant women attending the antenatal care clinics in primary health center in Hodeida city, Yemen. Clean voided mid-stream urine samples were collected and cultured. Isolated bacteria were characterized by standard laboratory tests, and antibiotic sensitivity was performed by disk diffusion method. Clinically significant bacterial growth was detected in 30 (54.5%) of the samples examined. Escherichia coli was the most frequent etiological agent of UTI (50 %) followed by Staphylococcus aureus.........

Keywords: Bacteriuria, Escherichia coli, Hodeida,pregnant women, Urinary Tract Infection

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clinical practice. ClinChimActa. 2000 ; 301: 1–18.
[3]. Philip MH, David AB, Clemens JQ, Roger RD, Deborah E, Mary PF, et al.,. AUA Guideline for the Diagnosis and Treatment of
Interstitial Cystitis/Bladder Pain Syndrome. AUA,185( 6), 2011, 2162–170.
[4]. Nicolle LE. Asymptomatic bacteriuria: when to screen and when to treat. Infect Dis Clin North Am, 17,2003,367–94.
[5]. Kincaid-Smith P, Bullen M. Bacteriuria in pregnancy. Lancet,191, 1965,395–9.

Abstract: Backgound: Chronic spontaneous urticaria (CSU) is a common skin disorder, which is rarely fatal, but significantly deteriorates the patient's quality of life (QOL). Some symptom domains such as itch, pain and associated wheals, as reported by the patient serves as the primary source of assessment. Aim: The study was designed to assess the QOL in Indian patients with CSU and its relation to the disease severity. Subjects and Methods: To measure impairment of QOL in CSU patients, we used the urticaria specific QOL instrument, Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) as well as dermatology specific QOL instrument, Dermatology Life Quality Index (DLQI)..........

Keywords: CSU , CU-Q2oL, DLQI, UAS, QOL.

[1]. Zuberbier T, Aberer W, Asero R et al. The EAACI/GA²LEN/EDF/WAO Guideline for the definition, classification, diagnosis and management of Urticaria. The 2013 revision and update. Allergy 2014;69: 868–887.
[2]. Pherwani AV, Bansode G, Gadhia S. The impact of chronic urticaria on the quality of life in Indian patients. Indian J Dermatol 2012;57:110-3.
[3]. Mynek A, Zalewska-Janowska A, Martus P, Staubach P, Zuberbier T, Maurer M. How to assess disease activity in patients with chronic urticaria? Allergy. 2008;63:777-80.
[4]. Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI): A simple practical measure for routine clinical use. Clin Exp Dermatol 1994;19:210-16.
[5]. Baiardini I, Pasquali M, Braido F, Fumagalli F, Guerra L, Compalati E, et al. A new tool to evaluate the impact of chronic urticaria on quality of life: chronic urticaria quality of life questionnaire (CU-Q2oL). Allergy. 2005;60:1073-8.

Abstract: The lobulated form of the spleen in early developmental phase is represented by notches at later period which occur at the superior border. The superior border which separates the gastric impression from the diaphragmatic surface has notches near its lateral end. Methods: 40 adult spleens available in the department were studied and the splenic notches with respect to the borders were noted. Results: Two specimens showed notches only on inferior border, one specimen with notches on both superior and inferior borders and three spleens are without any notches on all borders

Keywords: spleen, notches, borders, variations.

[1]. Sadler, T.W. Langman‟s Medical Embryology. Baltimore; Lippincott Williams & Wilkins, 9th ed; 2000: 277.
[2]. Standring, S,Gray's anatomy. The anatomical basis of clinical practice. London UK , Elsevier Churchill Livingstone, 40th ed ,2005: 1191-1195.
[3]. Rosse C, Gaddum R (Eds). Hollinshead's Textbook of Anatomy. Philadelphia; Lippincott-Raven: 1997:556
[4]. Jakubovsky J, Porubsky J. Functional morphology of the spleen. The current knowledge. Bratisl Lek Listy 1995; 96:637-641.
[5]. Safak AA, Simsek E, Bahcebasi T. Sonographic Assessment of the Normal Limits and Percentile Curves of Liver, Spleen and Kidney Dimensions in Healthy School-Aged Children. J Ultrasound Med 2005; 24; 1359-1364

Abstract: Case Report Focuses On Placement Of Immediately Loaded Implants In Posterior Edentulous Mandible Bilaterally. It Is Follow Up Study Of 2 Years. A Total Of 6 Immediately Loaded Mandibular Dental Implants Were Placed In Medically Compromised Patients. All Immediately Loaded Implants Were Torque Tested To More Than 30 Ncm. All Were Provisionally Restored In 24 Hrs. The Survival Rate For Immediately Loaded Implants Was 100%. Immediately Loaded Implants Have Predictable Clinical Success Along With Psychological And Esthetical Benefits To The Patient

Keywords: Dental Implant, Functional Loading, Immediate Loading, Primary Stability

[1]. Laviv A, Levin L, Usiel Y et al, Survival of immediately provisionalized dental implants, A case-control study with up to 5 years follow-up, Clin Implant Dent Relat Res 12,e23, 2010
[2]. Galli F, Capelli M, Zuffetti F et al, Immediate non-occlusal vs. early loading of dental implants in partially edentulous patients, A multicentre randomized clinical trial. Peri-implant bone and soft-tissue levels. Clin Oral Implants Res 19,546, 200843
[3]. Sennerby L, Gottlow J, Clinical outcomes of immediate/early loading of dental implants, A literature review of recent controlled prospective clinical studies, Aust Dent J 53,S82, 2008
[4]. Daniel Boedeker, John Dyer, Richard Kraut, Clinical Outcome of Immediately Loaded Maxillary Implants, A 2-Year Retrospective Study. J Oral Maxillofac Surg 69,1335-1343, 2011
[5]. Degidi M, Nardi D, Piattelli A, Immediate loading of the edentulous maxilla with a final restoration supported by an intraoral welded titanium bar, A case series of 20 consecutive cases. J Periodontol 79,2207, 2008

Abstract: Genetic research in familial forms of isolated GH deficiencies found a molecular abnormality in 50% of cases (n = 5/10). The search for a mutation in the GH1 gene was negative. Involvement of the GHRH-R gene is exclusive. Three mutations were identified : PL 144 Histamine (-C-431 T> A); ALA5 ASoFsx 22 and C465- 91-1105-119 del 5291 bp. No genotype / phenotype correlation has been found for these mutations

Keywords: Isolated GH deficiency - GH1 gene - pituitary hypoplasia - GHRH-R gene - delay stature

[1]. Dattani. Mt And Robinson. Ic. The Molecular Basis For Developmental Disorders Of The Pituitary Gland In Man. Clinical
Genetics 2000 ; 57 : 337-346.
[2]. Parks. J.S, Abdul-Latif. H, Kinoshita. E, Meacham. L.R, Pfaffle. R.W, Brown. M.R.Genetic Of Growth Hormone Gene
Expression. Horm. Res. 1993 ; 40 = 54 - 61.
[3]. Barlier. A, Vallette-Kasic. S, Manavela. M, Perez. M, Diaz. A, Pellegrini- Bouiller. I, Enjalbert.A, Brue. Th. Développement
Hypophysaire Et Pathologie Des Facteurs De Transcription.Annales D'endocrinologie 2000 ; 61, 3 : 201 - 207.
[4]. Lopez-Bermejo.A, Buckwayck. Rosenfeld. R.G. Genetic Defects Of The Growth Hormone Insulin-Like Growth Factor Axis.
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Deficiency*. Clin. Endocrinol. Metab. 1994 ; Vol 78, (1 ) : 11 - 14

Abstract: The genetic study of 53 Algerian children with congenital multiple hypopituitarism found a mutation of transcription factors in 20.7% of cases (n = 11). Mutations in Prop1 are familial (90% of cases) and predominant (n = 10 /11). Among them, the R73C mutation is majority (07 out of 10) and appears to be specific to the Maghreb. No genotype / phenotype correlation was found. In one case a Pit1 mutation is identified: exon 1 PAL 32 Fsx18. This has not been previously reported. No molecular abnormalities were found in the case of ectopic posterior pituitary (n = 29).

Keywords: GH deficiency congenital - multiple congenital hypopituitarism - prop1 - Pit1 - post ectopic pituitary.

[1]. Adams Baum. C, Gini Sty. D, Chaussain. JL, Kalifa. G, Houang. M, Andre. CH, Richard. I. Imagerie par résonance magnétique des hypopituitarismes non tumoraux de l'enfant.Revue d'Imagerie Médicale 1993 ; 5 : 251-257.
[2]. Dinatale. B, De Angelis. R, Luke. Zic. M, Pellini. C, Chiu Mello. G. Neuro- Radiologic Diagnosis of the hypothalamo-hypophysical region in children with hypopituitarism. Minerva Endocrinol 1993 ; 18 : 48-52.
[3]. Cohen. LE, Rado Vick. S. Molecular basis of combined pituitary hormone deficiencies. Endocr Rev, 2002 ; 23 (4) : 431-442.
[4]. Cu Shman. LJ, Showalter. AD, Rhodes. SJ. Genetic deficits in the development and function of the anterior pituitary gland. Ann Med 2002 ; 34 : 179-191.
[5]. Barlier. A, Vallette-Kasic. S, Ma Navela. M, Perez. M, Diaz. A, Pelle Grini- Bouillcri, Enjalbert. A, Brue. TH. Developpement hypophysaire et pathologie des facteurs de transcription. Ann d'Endocrin 2000 ; 61 : 201-207.