Abstract: To compare the efficacy of chlorhexidine–alcohol and povidone–iodine as preoperative antiseptic skin
preparation for prevention of surgical site infection (SSI)
Materials and methods: A total of 311 eligible Patient who underwentSurgery were recruited in the study after
fulfilling all the eligibility and exclusion criteria. Patients were randomized into two groups (153 in chlorhexidine–
alcohol group and 158 in povidone–iodine group) by a computer-generated randomization table. Patients were followed
for a period of 30 days in postoperative period to monitor for SSI.
Results: The rate of SSI in the chlorhexidine–alcohol group is 5.4% and that of the povidone–iodine group is 8.6%.
E. coli, K. pneumoniae, and Acinetobacter baumannii were the most common organisms isolated. E. coli was found in 9.5%
of the total SSI cases.......
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