Abstract: Objective: Free radical-mediated oxidative stress has been implicated in the pathogenesis of thyroid disorders. Hypothyroidism is a common thyroid disorder. The aim of this study was to investigate the influence of levothyroxine (LT4) therapy on oxidative stress marker Malondialdehyde (MDA) level in hypothyroid patients.
Design: This Randomized clinical trial was conducted to compare MDA level in hypothyroidism before and after treatment by LT4.
Methods: 30 patients with newly diagnosed hypothyroidism and 30 healthy age matched subjects of both sexes as the control group were......
Key Word: Hypothyroidism, Oxidative Stress, Reactive oxygen species, Levothyroxine
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