iosr-JDMS   Volume-21 ~ Issue-6 ~ June 2022

Abstract: Background: Musculoskeletal pain is very common around the world. The study was done to determine the efficacy of the formulation made of turmeric and Boswellia extract (PFK300, Rhuleave-K®) for acute musculoskeletal pain. Materials and Methods: In this prospective randomized double-blind study, 40 subjects were randomized in an allocation concealed 1:1 ratio to receive a single dose of 500 mg of PFK300 (Rhuleave-K®) or placebo. The primary outcome was the sum of pain intensity difference at 6 hours (SPID6) evaluated by the Numerical Rating Scale (NRS) and total pain relief (TOTPAR6) evaluated by categorical pain relief scale (PRS) every 30 minutes up to 6 hours. The secondary outcomes.......

Keywords: Turmeric; Boswellia; Musculoskeletal pain; Pain measurement; Pain intensity; Pain relief.

[1]. Arendt-Nielsen L, Fernández-de-las-Peñas C, Graven-Nielsen T. Basic aspects of musculoskeletal pain: from acute to chronic pain. Journal of Manual & Manipulative Therapy. 2011;19(4):186–193. http://www.tandfonline.com/doi/full/10.1179/106698111X13129729551903. doi:10.1179/106698111X13129729551903
[2]. Suri P, Morgenroth DC, Kwoh CK, Bean JF, Kalichman L, Hunter DJ. Low back pain and other musculoskeletal pain comorbidities in individuals with symptomatic osteoarthritis of the knee: data from the osteoarthritis initiative. Arthritis care & research. 2010;62(12):1715–1723. https://onlinelibrary.wiley.com/doi/10.1002/acr.20324. doi:10.1002/acr.20324
[3]. Cieza A, Causey K, Kamenov K, Hanson SW, Chatterji S, Vos T. Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet. 2020;396(10267):2006–2017.
[4]. Conaghan PG, Dickson J, Grant RL. Care and management of osteoarthritis in adults: summary of NICE guidance. BMJ. 2008;336(7642):502–503. https://www.bmj.com/lookup/doi/10.1136/bmj.39490.608009.AD. doi:10.1136/bmj.39490.608009.AD
[5]. Bost J, Maroon A, Maroon J. Natural anti-inflammatory agents for pain relief. Surgical Neurology International. 2010;1(1):80. http://www.surgicalneurologyint.com/text.asp?2010/1/1/80/73804. doi:10.4103/2152-7806.73804.

Abstract: Background: Traumatic macular hole(TMH) can occur immediately after the ocular trauma or a few weeks later. TMH could result from a rupture of the fovea due to impact of the injury in early onset cases and in late onset could be due to deroofing of the cysts in chronic cystoid macular oedema. Spontaneous closure of macular hole is rare but it has been reported in young adults with small macular hole. It is associated with good visual prognosis. Optical coherence tomography(OCT) plays an essential role in patient management. We report a case of 26 year old male with TMH managed conservatively with monitoring on serial OCT scans. Conclusion: Serial clinical visits with OCT examination can help to monitor the disease and timely surgical intervention when required. Three months of observation can be considered before deciding the surgical management for TMH.

Keywords: Traumatic macular hole, OCT , Spontaneous closure

[1]. Yamashita T, Uemara A, Uchino E, Doi N, Ohba N. Spontaneous closure of traumatic macular hole. Am J Ophthalmol. 2002;133:230–5. [PubMed: 11812427]
[2]. Faghihi H, Ghassemi F, Falavarjani KG, Saeedi Anari G, Safizadeh M, Shahraki K. Spontaneous closure of traumatic macular holes. Can J Ophthalmol. 2014;49:395–8. [PubMed: 25103660]
[3]. A. P. Finn, X. Chen, C. Viehland et al., "Combined internal limiting membrane flap and autologous plasma concentrate to close a large traumatic macular hole in a pediatric patient," Retinal Cases & Brief Reports, 2018.
[4]. J. B. Miller, Y. Yonekawa, D. Eliott et al., "Long-term follow- up and outcomes in traumatic macular holes," American Journal of Ophthalmology, vol. 160, no. 6, pp. 1255–1258, 2015
[5]. H.Chen,W.Chen, K.Zheng et al., "Prediction of spontaneous closure of traumatic macular h\ole with\ spectral domain optical coherence tomography,"Scientific Reports,5,Article ID 12343,2015

Abstract: Background: Besides developed countries, coronary artery disease (CAD) is becoming a major cause of mortality and morbidity in the developing world now. Hypertension, diabetes mellitus and chronic kidney disease (CKD) are considered as some major comorbidities for coronary artery disease patients. Objectives: The aim of this study was to evaluate the frequencies of having hypertension, diabetes mellitus and chronic kidney disease among coronary artery disease patients. Methods: This prospective observational study was conducted in the department of Cardiology, Shaheed Ziaur Rahman Medical College, Bogura, Bangladesh during the period from June 2020 to May 2021.........

Keywords: CAD, Hypertension, Diabetes mellitus, Chronic kidney disease, coronary artery disease, CKD.

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Abstract: Aim: The purpose of this study was to evaluate and measure the effect of repeated bonding on the shear bond strength(SBS) and adhesive remnant index (ARI) of orthodontic brackets bonded using conventional primer(CP) and self etching primer(SEP). Materials and Methods: Twenty eight maxillary first premolars were collected and divided into two equal groups. In group I, the teeth were etched with 37% phosphoric acid, a sealant was applied, and the brackets were bonded with Transbond XT (3M Unitek). In group II, the teeth were etched with self etching primer (Transbond Plus,3M Unitek) and bonded with Transbond XT. In each group, the teeth were bonded and debonded 3 times with the same adhesive.......

Keywords: Repeated Bonding,Shear Bond Strength,Transbond XT,Transbond Plus

[1]. Babu NV,Joseph R.Dr.Michael Bunocore-Adhesive Dentistry-1995.J Conserv Dent 2005;8(3):43-44.
[2]. Coronal AB,Varanjo B,Valdiviezo P.Adhesive Systems Used in Indirect Restorations Cementation: Review of the Literature .Den J 2019;7(3):71-75.
[3]. Pus MD,Way DC. Enamel loss due to orthodontic bonding with filled and unfilled resins using various clean-up techniques. Am J Orthod 1980 Mar;77(3):269-283.
[4]. Giannini M, Makishi P, Ayres APA, Vermelho PM, Fronza BM, Nikaido T, Tagami J. Self-Etch Adhesive Systems: A Literature Review. Brazilian Dental Journal 2015; 26(1): 3-10.
[5]. Oonsombat C,Solomon M,Warren JJ,Bishar SE.Comparison of bonding time and shear bond strength between a conventional and a new integrated bonding system.The Angle Orthodontist.2005;75(2):237-242.

Abstract: Aims & objectives: Hidradenitis Suppurativa (HS) is a chronic, inflammatory disease affecting the apocrine glands of the axillary, groin and mammary regions with significant physical and psychosocial sequelae Surgical excision of the affected tissue is the gold standard. we present our experience in the operative management of severe hidradenitis suppurativa axilla with radical excision and immediate reconstruction with Thoracodorsal artery perforator flap and analyze the results of the treatment.. Methods: Over 4 years, we enrolled 5 patients with HS of the axilla who underwent surgical excision with reconstruction with TDAP flap reconstruction . We evaluated intraoperative and post-operative data, quality of life , pain/discomfort before and after surgery.All patients were operated under general anaesthesia. Results: Patients who underwent TDAP flap reconstruction......

Keywords: hydradenitis suppurativa; TDAP flap;Reconstruction of the axilla,GENERAL ANASTHESIA

[1]. Jemec GBE. Clinical practice: hidradenitis suppurativa. N EnglJ Med 2012;366:158-64.
[2]. Collier F, Smith RC, Morton CA. Diagnosis and management of hidradenitis suppurativa. BMJ; 2013:346.
[3]. Ortiz CL, Castillo VL, Pilarte FS, et al. Experience using the thoracodorsal artery perforator flap in axillary hidradentitissuppurativa cases. Aesthetic Plast Surg 2010;34:785-92.
[4]. Bu¨yu¨kas‚ik O, Hasdemir AO, Kahramansoy N, et al. Surgical approach to extensive hidradenitis suppurativa. Dermatol Surg 2011;37(6):835-42.
[5]. Matusiak L, Bieniek A, Szepietowski JC. Hidradenitis suppurativa and associated factors: still unsolved problems. J Am
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Abstract: Background and Objective : Lymph node swellings are one of the commonest clinical presentation of patients. FNAC is usually the first step in evaluation of enlarged lymph node. It is simple, rapid, inexpensive diagnostic procedure. The objective of study was to correlate FNAC and histopathological findings. Materials and Method : A total of 75 clinically diagnosed cases of lymphadenopathies referred to Dr Lal Path Lab between April 2020 to March 2022 were included in the study. FNAC results of 50 cases were compared with the histopathological findings......

Keywords: FNAC, Lymph nodes, Histopathology

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Abstract: Congenital diaphragmatic hernia is characterized by an embryonic defect in a diaphragmatic dome, the incidence of which varies between 1/3000 to 1/5000 live births. The posterolateral seat through the foramen of Bochdalek accounts for 80% of congenital diaphragmatic hernias. We report a case of right congenital diaphragmatic hernias (CDH) with late onset, as well as data from the literature. The objective of this work is to focus on the diagnostic difficulties and the management of this pathology. Diagnosis and antenatal care are important elements in reducing patient mortality and morbidity. The combination of pulmonary arterial vasculopathy and pulmonary hypoplasia determine the vital prognosis, which justifies planned treatment in a neonatal center..

Keywords: Hernie, diaphragme, diagnostic antenatal

[1]. Soukaina Ait Hmadouch, Amina Barkat. La hernie diaphragmatique congénitale: une pathologie pas toujours facile à diagnostiquer. PAMJ - 36(353). 27 Aug 2020.
[2]. A. Benachi a, ⁎, b , J. Saada a, b, J. Martinovic b, c, P. de Lagausie b, d, L. Storme b, e, J. Jani f. Hernie congénitale du diaphragme : prise en charge anténatale . Elsevier Masson SAS.08/07/11
[3]. Pei-Hsin Chao 1, Chung Bin Huang , Chieh-An Liu , Mei Yung Chung , Chih-Cheng Chen , Feng Shun Chen , Mei-Chen Ou-Yang , Hsin Chun Huang. Hernie diaphragmatique congénitale en période néonatale : bilan de 21 ans d'expérience. Elsevier.2010.
[4]. R. Oulahyanea,b, A. Bentalhaa,b,c, A. Abbassib, M. Kisraa,b, A. El koraichia. Hernie diaphragmatique congénitale antérolatérale : à propos d'un cas.Elsevier Masson SAS. 2014.
[5]. A. Labbéa,b, K. Costea,b, P.-J. Déchelottec. Hernie congénitale du diaphragme : mécanismes de l'hypoplasie pulmonaire. Elsevier Masson SAS. 2011.

Abstract: Background: Epilepsies are the most common chronic disabling neurological conditions. Late-onset epilepsies are always suspicious and often pose the problem of their etiology. It is an epileptic disease whose first epileptic seizure begins from the age of 25 years. The aim of this study was to study the epidemiological characteristics of epilepsies in subjects whose first epileptic seizure begins from the age of 25 years. Materials and Methods: The study population includes all Algerian patients whose age of onset of the first seizure is 25 years or more, recruited during the period from January 2008 to December 2016 at ALI AIT IDIR Hospital in Algiers. Patient.......

Keywords: Late onset epilepsy, Average age, Sex ratio, Incidence of late epilepsy, Age pyramid, Geographical origin, Wilayas of Algeria, Wilaya of Algiers, Western wilayas, Eastern wilayas, Southern wilayas.

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Abstract: Background: EEG is a non-invasive, non-painful examination, it makes it possible to assess spontaneous cerebral functioning. The contribution of the EEG to the diagnosis of the epileptic nature of a paroxysmal event is valuable. The contribution of the EEG to the diagnosis of a paroxysmal event must be integrated into the bundle of clinical arguments, and alone cannot constitute the key element of the diagnosis. The objective of our study was to determine EEG findings of late epilepsy in the Algerian population. Materials and Methods: The study population includes all Algerian patients whose age of onset of the first seizure is 25 years or more, recruited during the period from January 2008 to December 2016 at ALI AIT IDIR Hospital in Algiers........

Keywords: EEG findings, Focal abnormalities, Generalized abnormalities, Temporal topography, Frontal topography, Temporal epileptic abnormalities, Frontal epileptic abnormalities

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Abstract: Lymphangiomyomatosis-Tuberous sclerosis(LAM) is a rare multi system involving disease which usually effects the women of reproductive age. It is estimated to affect 3.4-7.8/1,000,000 women worldwide. We report a case of 36 yr old woman who presented initially with cough and weight loss. She was evaluated and diagnosed as LAM-TSC with multisystem involvement..

Keywords: Lymphangiomyomatosis-tuberous sclerosis, weight loss ,multisystem involvement

[1]. Rhee J, Adial A, Gumpeni R, et al. Lymphangioleiomyomatosis: A Case Report and Review of Literature. Cureus 2019;11(1): e3938.
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[3]. Smolarek TA, Wessner LL, McCormack FX, Mylet JC, Menon AG, Henske EP. Evidence that lymphangiomyomatosis is caused by TSC2 mutations: chromosome 16p13 loss of heterozygosity in angiomyolipomas and lymph nodes from women with lymphangio-myomatosis. Am J Hum Genet 1998; 62(4): 810–5.
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[5]. Strizheva GD, Carsillo T, Kruger WD, Sullivan EJ, Ryu JH, Henske EP. The spectrum of mutations in TSC1 and TSC2 in women with tuberous sclerosis and lymphangiomyomatosis. Am J Respir Crit Care Med 2001;163(1):253–8..

Abstract: AIMS & OBJECTIVES- BENIGN SCHWANNOMAS ARE the most common tumour of peripheral nerve. we present our experience in operative management of schwannomas involving extremities and analyse results of treatment. MATERIALS AND METHODS- This study involved 10 cases of schwanommas of extremities admitted in Srivenkateswara medical college,Tirupati, over a period of 3 yrs (2015-2019). Criteria for inclusion is the presence of schwanommas of extremity confirmed by imaging.. Assessment was done by assessing functional and cosmetic appearance of the patients. Results: There were five males and six females with a mean age of 37.6 (range: 17–62) years. 7 tumours originated from major peripheral nerves and 3 involved digital nerve branches.2 cases of schwanomma diagnosed in lower extremities involving sciatic nerve. In upper limb, 1 case involved ulnar nerve, 2 median nerve at.......

Keywords: Neurilemmoma; neuroma; perineural fibroblastoma; peripheral nerve; schwannomas;Regional Anesthesia.

[1]. Gosk J, Gutkowska O,Urban M,Wnukiewicz W, Reichert P,Ziokpwski P.Results of surgical treatment of schwanommas arising from extremities.Biomed Res Int 2015;2015:547926
[2]. Gosk J.,Zimmer K.,Rutowski R .Peripheral nerve tumours- diagnostic and therapeutical basics.Folia Neuropathologica.2004;42(1):31-35.
[3]. Zhou J .,Man X.Y., Zheng M.,Cai S.Q.Multiple plexiform schwanomma of a finger.Eueropean Joural of Dermatology.2012;22(1):149-150:10.1684/ejd.2011.1609
[4]. Pilavaki M., Chourmouzi D.,Kiziridou A., Skordalaki A., Zaarampoukas T., Drevelengas A.Imaging of peripheral nerve sheath tumours with pathologic correlation :pictorial review.European Journal of Radiology.2004;52(3):229-239.doi:10.1016/j.ejrad.2003.12.001.
[5]. Kim SM, Seo sw,Lee JY, Sung KS.Surgical outcome of schwannomas arising from major peripheral nerves in lower limb.Int Orthop ;2012;36(08):1721-1725.

Abstract: Introduction:Hypospadias is a congenital condition characterized by tissue hypoplasia of the ventral aspect of the penis, with incidence of one (0.3%) in 300 males. There is an increase incidence in those with first-degree relatives having hypospadias to about 13 times more than those without family history. Aim of the study: To find out that Snodgrass is the more appropriate treatment for distal penile hypospadias by comparing two surgical techniques. Methods: This is a prospective comparative case-control study, the study was carried out in the Department of Pediatric Surgery, Dhaka Shishu Hospital.......

Keywords: Tubularized, Incised-Plate Urethroplasty, Snodgrass, Appropriate, Distal Hypospadias, Meatus & Glans

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Abstract: L'artériopathie calcifiante urémique est une pathologie sévère et de mauvais pronostic avec une prévalence de 5 % chez les patients en dialyse1 et une mortalité atteignant 60-80 % à un an 2. Elle est caractérisée par une occlusion des micro-vaisseaux du tissu adipeux sous cutané et du derme 3qui se manifeste cliniquement par des lésions cutanées ischémiques très douloureuses présentent sous forme d'induration, de plaques, de nodules, de livedo ou de purpura4......

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