Abstract :The purpose of this paper is to explore an Ordinary Differential Equation (ODE) model of cancer immunotherapy. Initially, we provide an overview of cancer immunotherapy treatment method, as well as key mathematical concepts. Subsequently, we conduct a comprehensive analysis of the model proposed by De Pillis et al., which describes tumor growth in the absence of treatment.
Without treatment, (as we restricted our study here in this paper) tumor development (cancer cell growth) occurs rapidly, leading....
Keywords: SIR; immunotherapy, cancer, cancer cells, immune cells, treatment. NSFD; RK4.
[1]. Abbal, M., And Pr Henri Roche, "Immunité Et Cancer," DFGSM3 2012/2013.
[2]. Altrock, P., M., Lin L. Liu, And Franziska Michor, "The Mathematics Of Cancer: Integrating Quantitative Models," Page 730.
[3]. Costes,V., F.P. Chatelet, "La Cellule Cancéreuse Et Le Tissu Cancéreux (Chapitre 8)," Mai 2005, Page 01.
[4]. Goel, N. S., Maitra, S. C., Montroll, E. W. (1971). On The Volterra And Other Nonlinear Models Of Interacting Populations. Reviews Of Modern Physics, 43(2), P 231.
[5]. Hahnfeldt,P., D. Panigrahy, J. Folkman, And L. Hlatky, "Tumor Development Under Angiogenic Signaling: A Dynamical Theory Of Tumor Growth, Treatment Response, And Postvascular Dormancy," Cancer Research, Vol. 59, No. 19, Pp. 4770-4775, 1999.