Abstract: Chinese herbal medicine called Tripterygium wilfordii Hook. F. (TwHF) has a lot of metabolites. It has drawn increasing attention in studies and clinical research because of its established anti-inflammatory and immune-regulating properties. Traditional Chinese medicine may be seen in the extraction and processing of TwHF for medicinal use. TwHF, however, is poisonous. The development of TwHF medicines now depends on optimization of TwHF formulations. In order to serve as a guide for Tripterygium wilfordii Hook F's potential future therapeutic use, this review provides an overview of the plant's current clinical use as well as the findings of investigations into its mechanisms and toxicity
Key words: Autoimmune illnesses, Tripterygium wilfordii Hook. F., alkaloids, immunoregulatory mechanisms, toxicity.
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