iosr-JPBS   Volume-12 ~ Issue-6 ~ Nov-Dec 2017

[1] Jensena JL, Barkvoll P. Clinical Implications of the Dry Mouth:Oral Mucosal
[2] Diseases.Annals of the New York Academy of Sciences. 1998. 842:1, 156–
[3] 162. http://dx.doi.org/ 10.1111/j.1749-6632.1998.tb09643.
[4] AI Kholani, Comparison between the Efficacy of Herbal andConventional Dentifrices on Established Gingivitis, Dental Research Journal (Isfahan). Springer; 2011. 8(2): 57-63.
[5] Ersoy, M; Tanalp, J; Ozel, E; Cengizlier, R; Soyman, M; The allergy of toothpaste: a case report. AllergoletImmunopathol,2008, 36(6),368-70.

[1]. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127(12), 2008, 2893-2917.

[2]. Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E, Feuer EJ, Thun MJ. Cancer statistics. CA. Cancer J Clin, 54(1), 2004, 8-29.
[3]. Pierce JG and Parsons T F. Glycoprotein Hormones: Structure and Function. Annual Review of Biochemistry, 50(1), 1981, 465-495.

[4]. Fritz MA and Speroff L. Female infertility. In Clinical Gynecologic Endocrinology and Infertility, 8th edition. Philadelphia: Lippincott Williams and Wilkins: 2011; 1137-1190. [5]. Broer SL, Broekmans FJ, Laven JS, Fauser BC. Anti-mullerian hormone: ovarian reserve testing and its potential clinical implications. Hum Reprod Update, 20(5), 2014, 688-701.

[1]. V.Kumar,N.Fausto, Abul K. Abbas, S,Cotran, Ramzi,L.RobbinsandStanley, Robbins and otran Pathologic Basis of Disease (7th ed.). Philadelphia, Pa.: Saunders2005,1194-1195.
[2]. S. Bansal, S. Beg, A. Asthana, B. Garg, G.S. Asthana, R. Kapil, B. Singh, QbD-enabled Systematic Development of Gastroretentive Multiple-unit Microballoons of Itopride Hydrochloride, Drug Delivery,23(2), 2016, 437-451.
[3]. S. Dhiman, A. Asthana, A.K. Tiwary, M. Jindal and G. Shilakari, Development and Evaluation of Novel Cordia Myxa Fruit Gum Based Mucoadhesive Tablets for Gastroretentive Delivery of Losartan Potassium, Journal of pharmaceutical science and research, 7(9)2015, 652-661.
[4]. S. Dhiman, A. Asthana, A.K. Tiwary, M. Jindal and G. Shilakari, Cordia Myxa Polysaccharide-G-Poly(Acrylonitrile) Co-Polymer Based Mucoadhesive Gastroretentive Delivery of Captopril, International Journal of Pharmaceutical Science and Research, 7(1) 2017 1000-13.
[5]. S. Bansal, S. Beg, B. Garg, A. Asthana, G.S. Asthana, B. Singh,Qbd-Oriented Development and Characterization of Effervescent Floating-Bioadhesive Tablets of Cefuroxime Axetil. AAPS Pharmaceutical Science and Technology" 17(5), 2016, 1086-99..

[1]. Fawole, O.I. &Onadeko M.O. (2001). Knowledge and Mana- ement of Malaria in Under Five Children by Primary HealthCare Workers in Ibadan South East Local Government Area. Nigeria. Post Graduate Medical Journal 8 (1): 1-5
[2]. WHO(1998a) Malaria, WHO Information Fact Sheet No 94 Geneva, W.H.O press officeSwitzerland. : 1 -6
[3]. Lucas, A.O. and Gilles H.M. (1998). A New Short Textbook of Preventive Medicine for the Tropics: Malaria,Great Britain ELBS with Edward Arnold.Publishers :188 - 192.. [4]. Mathers C.D, Mafat D, Inoue M, Rao C, Lopez A.D. (2005) Counting the dead and what they died from: an assessment of the global status of cause of death data. Bull World Health Organ;83:171–77.
[5]. Murray C.J.L, Lopez A.D.(1996)Global Health Statistics: A Compendium of Incidence, Prevalence and Mortality Estimates for Over 200 Conditions.Cambridge: Harvard University Press.

[1]. Satyanarayana T, P. Dwarakanadha reddy, D.Swarnalatha, Anjana A Mathews, Hypoglycemic effect of a Polyherbal extract on normal and streptazotocin induced diabetic rats, International Journal of pharmacy and pharmaceutical sciences ISSN-0975-1491, Vol2,Issue 3,2010.
[2]. Chandra shekhar Joshi, Ekambaram Sanmuga Priya, and Subramanian VenkataramanHypoglycemic and antilipidperoxidative effects of a Polyherbal formulation, Diakyur, in Experimental animal models. Journal of health sciences, 53 (6) 734-739 (2007).
[3]. Roger Walker,Cate Whittlesea : Clinical Pharmacy and Therapeutics, 4th edition, Churchil living stone 2007; 632
[4]. MycekMJ,HarveRA,ChampaPC,etal,Lippincott'sillustratedReviews;pharmacologyNewyork, Lippincott Willium's & Wilkins 2004; 255-262.
[5]. Rakha PS, Kuttan G, Kuttan R. Antioxidant activity of Brahma rasayana. Indian J Exp Biol 2001 ; 39: 447-452.

[1]. Venkatachandrudu, M. And Radhakrishnaiah, K. 2009. Cadmium induced histopathological changes in liver and muscle of the fresh water fish, Labeo rohita . J. Ecotoxic Envir Monit., 19 (3): 265-272.
[2]. Konstantinos C. And Valsamidou. A. V. 2011. Removal of Nickel Copper Zinc and Chromium from Synthetic and industrial waste water by electrocoagulation, Int.J Environ. Sci.1 (5): 698-703.
[3]. Martin, P. Devaprasanth and S.Arivoli, S. 2008. Biochemical study of freshwater fish Catla catla with reference to mercuric chloride.Iran.J.Environ.HLTH.Sci.Eng.,5,109-116.
[4]. Finney, D.J. 1971. Probit analysis, 3rd edition, (London : Cambridge University press), P.20.
[5]. Lowry, O.H., Rose Brough, N.J., Farr, A.L. and Randall, R.J.1951. Protein measurements with the folin phenol reagent.J.Biol.chem., 193: 265-275

[1]. Shenoi P.M. Management of Chronic Suppurative Otitis Media. Scott Brown's text book of Otolaryngology.5th Edition, 1988; 5(3):215.
[2]. Verhoeff M, van der Veen EL, Rovers MM, Sanders EM, &Schilder AGM. Chronic Suppurative Otitis Media: A Review. International Journal of Pediatric Otorhinolaryngology. 2006; 70 (1): 1–12.
[3]. WHO. (2004). Chronic Suppurative Otitis Media Burden of Illness and management options. Report of WHO expert committee. Geneva: WHO, 2004.
[4]. Harshika YK, Sangeetha S, &Prakash R. Original Research Article Microbiological profile of CSOM and their antibiotic sensitivity pattern in a tertiary care hospital. Int.J.Curr.Microbiol.App.Sci. 2015; 4(12): 735–43.
[5]. Dayasena RP, Dayasiri MBKC, Jayasuriya C, &Perera DSC. Aetiological agents in Chronic Suppurative Otitis Media in Sri Lanka. Australasian Medical Journal. 2011; 4(2):101-4.

[1]. Anonymous, WHO traditional Medicine Strategy 2002–2005. World Health Organisation, Geneva, Switzerland. (WHO/EDM/TRM/2002.1.). 2002.
[2]. S. Khan, Systems of medicine and nationalist discourse in India. Social Science and Medicine 62, 2006. 2786–2797.
[3]. R.M. Kunwar K.P. Shrestha and R.W. Bussmann, Traditional herbal medicine in far-west Nepal: a pharmalogical appraisal. Journal of Ethnobiology and Ethnomedicine 6, 2010. 35.
[4]. P.A. Cox, M. Balick, The ethnobotanical approach to drug discovery. Scientific American 270, 1994. 82–87.
[5]. Legris and VM. Meher – Homji, The Eastern Ghats: Vegetation and Bilclimatic aspects. Pros. Seminar on Resources development and environment in Eastern Ghats.Andhra University. Waltair. 1982. 1-7.

[1]. Brooks, W.H ., Le Dantec ,C . , Pers ,J. O. , Youinou ,P. ,and Renaudineau ,Y. (2010). Epigenetics and autoimmunity. J. Autoimmun. 34, J207–J219.
[2]. Benedek, T.G.(2006).The history of bacteriologic concepts of rheumatic fever and rheumatoid arthritis. Semin. Arthritis Rheum. 36, 109–123.
[3]. Silman, A.J .,and Pearson, J.E.(2002).Epidemiology and genetics of rheumatoid arthritis. ArthritisRes. 4(Suppl. 3) ,S265–S272.
[4]. Namekawa T, Snyder MR, Yen JH, Goehring BE, Leibson PJ, Wey and CM, et al.(2000). Killer cell activating receptors function as costimulatory molecules on CD4_CD28null T cells clonally expanded in rheumatoid arthritis. J Immunol ;165:1138–45.
[5]. Wagner UG, Koetz K, Weyand CM, Goronzy JJ.(1998) Perturbation of the T cell repertoire in rheumatoid arthritis. ProcNatlAcadSci U S A;95:14447–52.

[1]. Becket and stenlake, practical pharmaceutical chemistry, part 24th edition CBS publications and distributors, 2005, 157-168.
[2]. P.D. Sethi, HPLC quantitative analysis of pharmaceutical formulations CBS publications and distributors, 1st edition, 2001, 69-70.
[3]. B.K Sharma, instrumental method of chemical analysis, 23rd edition, goal publishers 2004.
[4]. Practical HPLC method development Lloyd R.Snyder, Joseph J. Kirkland, Joseph L. Glajch, second edition, 1, 420-430,686-704.
[5]. Validating chromatographic methods, David M.Bliesner. 1-4.

[1]. Christian, P.; Von der Kammer, F.; Baalousha, M.; Hofmann, T. Nanoparticles: Structure, properties, preparation and behaviour in environmental media. Ecotoxicology 2008, 17, 326–343.
[2]. Nochehdehi AR., Thomas S., Sadri M., Afghahi SSS. and Mehdi H. SM." Iron Oxide Biomagnetic Nanoparticles (IO-BMNPs); Synthesis, Characterization and Biomedical Application–A Review" J. Nanomed. Nanotechnol. (2017), 8:1:1 – 9.
[3]. Herlekar M. and Barve.S. "optimization of microwave assisted green synthesis protocol for iron oxid nanoparticles and its application for simultaneous removal of pollutants from domestic sewage" international j of advance res. (2015) (4):331 – 345. Thakur S. and Karak N." One-step approach to prepare magnetic iron oxide/reduced graphene oxide nano-hybrid for efficient organic and inorganic pollutants removal" Materials Chemistry and Physics, (2014)3: 425-432.
[4]. Teje AS. and Pei- Yoongk."synthesis properties and application of magnetic iron oxid nanoparticles ,Prog. Cry. Grow. Charac. Mat , (2009)55: 22 – 45.
[5]. Rieznichenko L., Doroshenko A., Gruzina T., Dybkova S., Polova Z., Ulberg Z. and Ivan C" Iron Nanoparticles' effectiveness for new antianemic preparations development" Nanocon, .(2013) 10:16 – 18.

[1]. Dr. Amitava Bora, Dr. Abhirup Goswami, Dr. Gautam Kumar Kundu, Dr. Biswajit Ghosh,
[2]. 2014: Antimicrobial Efficacy of few commercially available herbal and non-herbal toothpastes against clinically isolated human cariogenic pathogens, Journal of Nepal Dental Association, vol-14.
[3]. Andiara De Rossi, Danielly Cunha Araújo Ferreira, Raquel Assed Bezerra da Silva, Alexandra Mussolino de Queiroz, Léa Assed Bezerra da Silva, Paulo Nelson-Filho, 2014: Antimicrobial Activity of Toothpastes Containing Natural Extracts, Chlorhexidine or Triclosan, Brazilian Dental Journal, ISSN 0103-6440.
[4]. Benly. P, 2015: Comparison of the Bacterial Level by Pre Brushing and Post Brushing using Herbal and Fluoridated Toothpaste. Journal of pharmaceutical sciences and research, ISSN:0975-1459. Vol. 7(6).
[5]. Biju Thomas, Sunaina Shetty Y, Agrima Vasudeva, Veena Shetty, 2011: Comparative evaluation of Antimicrobial Activity of Triphala and commercially available Toothpastes: An in-vitro study, International Journal of Public Health Dentistry, 2(1): 8-12

[1]. Wroblewski L.E, Peek R.M Jr., Wilson KT.Helicobacter pylori and gastric cancer, factors that modulate disease risk. Clin.Microbiol. Rev. 2010; 23, 713-739

[2]. A Kaur, R Singh, R Sharma, S Kumar. Peptic ulcer: A review or etiology and pathogenesis. Int.Res.Jr.Pharm., 3(6), 34-38, 2012
[3]. Manjari V, Das UN. Oxidant stress, anti-oxidants, nitric oxide and essential fatty acids in peptic ulcer disease. Prostaglandins Leukot.Essent. Fatty Acids. 1998, 59 (6): 401-6
[4]. S. E. Lee, J. W. Lim, J. M. Kim, and H. Kim, "Anti-inflammatorymechanism of polyunsaturated fatty acids in Helicobacterpylori-infected gastric epithelial cells," Mediators of Inflammation, vol. 2014, Article ID 128919
[5]. Segal ED, Lange C. Covacci A et al. Induction of host signal transduction pathways by Helico bacter pylori. Proc.Natl.Acad.Sci.USA. 1997; 94: 7595-7599

[1]. J. J. Neumiller, J. R. White and R. K. Campbell, Sodium-glucose co-transport inhibitors: progress and therapeutic potential in type 2 diabetes mellitus, Drugs, 70(4), 2010, 377-85.
[2]. S. A. Nisly, D. M. Kolanczyk and A. M. Walton, Canagliflozin, a new sodium- Glucose cotransporter 2 inhibitor, in the treatment of diabetes, Am J Health Syst Pharm, 70, 2013, 311-319.

[3]. Harsharan Pal Singh, Ishpreet Kaur and Gunjan Sharma, Sodium Glucose Co-Transporters-2 (SGLT2) Inhibitors as a New [4]. Class of Anti-diabetic Drugs: Pharmacokinectics, Efficacy and Clinical Significance, Int J Pharm Sci Rev. Res. 33(1), 2015, 40-47.

[5]. B. Haas, N. Eckstein, V. Pfeifer, P. Mayer and M. D.S. Hass, Efficacy, safety and regulatory status of SGLT2 inhibitors: focus n canagliflozin, Nutr Diabetes, 4(11), 2014, e143