iosr-JPBS   Volume-4 ~ Issue-6

[1] Barnnet HL, Hunter BB (1972). Illustrated genera of imperfect Fungi- APS press,Minnesota.
[2] Bayewu RA, Amusa NA (1999). Biochemical changes in pawpaw fruit infected with fungi In: Bioscience Research Communication
11: 257- 261.
[3] Chan HT (1983). Handbook of Tropical Foods. Marcel Dekker New York pp 469-488.
[4] Charley VL (1999). The Prevention of microbiological spoilage in fresh fruit In: Journal of Science and Food Agriculture. 10: 399-
400.
[5] Duckwort RF (1966). Fruits and Vegetables. Per grammon Great Britain pp 162-165.
[6] Franzier WC,Westhoff DC (1991). Food Microbiology (3rd ed.) Tata Mc GrawHill publishing Company Ltd. New Delhi pp 17-21.
[7] Holtmeyer MG, Wallin JR (1981). Incidence and Distribution of airborne spores of Aspergillus flavus, In: Plant Disease 6: 54-60.
[8] Ihekeronye AI, Ngoddy PO (1985). Integrated Food Science and Technology for the tropics, Macmillan Publishers Ltd. London pp
385.
[9] Lloyd BB (1993). Fungi in food . An Overview In: Encyclopeadia of Food Science, Food Technology and Nutrition. Academic
Press Ltd. London pp. 4327-4337.
[10] Menzel C (1994). Tropical and subtropical Fruits. Encyclopeadia of Agricultural Science 4: 375-378. Robert AS, Ellen SN (1998).

[1] J.O. Duruibe, , M.O. Ogwuegbu, and J.N. Egwurugwu , Heavy metal pollution and human biotoxic effects , International Journal of
Physical Sciences, 2 , 2007,112-118 .
[2] C . Judith, l. Ruiz , G. Ciria, and S. Figueroa , Manganese inactivation of renal betaine aldehyde dehydrogenase from swine .
EXCLI Journal, 5, 2006, 140- 149 .
[3] U.S. EPA, Health effects support document for manganese. U.S.Environmental Protection Agency ,Washington ,DC ,2003, EPA
822 - R- 03- 003.
[4] IOM , Dietary Reference Intakes for Vitamin A, Vitamin K , Arsenic , Boron , Chromium ,Copper , Iodine , Iron , Manganese
,Myolybdenum ,Nickel ,Silicon , Vanadium ,Zinc .Food and Nutrition Board . Institute of Medicine . National Academy Press
,Washington ,2001, 10 -22.
[5] Z . Bijia , Effect of manganese of genital system of male mice .Toxic,1994, 04 -015 .
[6] WH. Huang , and JL . Lin , Acute renal failure following ingestion of manganese – containing fertilizer . Toxicol .Clin . Toxicol,
42,2004, 305- 307 .
[7] S. Leonhard –marek, ( 2000 ) : Why do trace elements have an influence on fertility . Tierarztliche Praxis Ausgabe Grobtiere
Nutztiere , 28,2000, 60 -65 .
[8] B. Yan zhang ; C. CHEN , and F. Liye , Effect of manganese on heat stress protein synthesis of new born rats . World J
Gastroenterol ,8, 2002, 114 -118 .
[9] WHO Guidelines for dringing –water guality , Health criteria and other supporting information. World Health Organization ,
Geneva ,1996, 2nd edition Vol 2.
[10] M. Joardar ,and A. Sharma , A comparison of clasto genecity of inorganic Mn administered in cationic and anionic forms in vivo .
Mutat Res , 240,1990.

[1] A. I. Aronson, W. Beckman, and P. Dunn, Bacillus thuringiensis and related insect pathogens Microbiol Rev., 50, 1986, 1-24.
[2] H. Hofte, & H. R. Whiteley, Insecticidal crystal proteins of Bacillus thuringiensis. Microbiol. Rev. 53, 1989, 242-255.
[3] S. C. MacIntosh, G. M. Kishore, F. J. Perlak, P. G. Marrone, T. B. Stone, S. R. Sims, R. L. Fuchs, Potentiation of Bacillus
thuringiensis insecticidal activity by serine protease inhibitors. Journal of Agricultural and Food Chemistry. 38, 1990, 1145–1152.
[4] Goldberg, L. J., and Margalit, J., (1977) A bacterial spore demonstrating rapid larvicidal activity against Anopheles serengetti,
Uranotaenia unguiculta, Culex univittatus, Aedes aegypti and Culex pipiens. Mosq. News. 37, 355-358.
[5] A. Krieg, A. Huger, G. Langenbruch, and W. Schetter, Bacillus.thuringiensis var tenebrionis; a new pathotype effective against
larvae of coleoptera. J. appl. Ent., 96, 1983, 500-508.
[6] J. S. Feitelson, J. Payne, & L. Kim, Bacillus thuringiensis; Insects and beyond. Bio/Technology. 10, 1992, 271-275.
[7] B. H. Knowles, Mechanism of action of Bacillus.thuringiensis Inectisidal -endotoxin. Adv. Insect Physiol. 24, 1994, 275-308.
[8] (http:/www.lifesci.sussex.ac.uk/home/Neil_Crickmore/Bt 2007)
[9] L. A. Bulla, L. I. JR., Davidson, K. J. Kramer, and B. L. Jones, Purification of insecticidal toxin from the parasporal crystal of
Bacillus thuringiensis subsp. Kurstaki. Biochemical and Biophysical Research communications 91, 1979, 1123-1130.
[10] L. Chang, R. Grant, A. Aronson, Regulation of the Packaging of Bacillus thuringiensis delta-endotoxins into Inclusions. Appl
Environ Microbiol 67, 2001, 5032-5036.

[1] Ahmed, S. and G. Stoll, (1996). Biopesticides. In: Biotechnology; Building on Farmers' Knowledge. Macmillan Education Ltd,
Bunders, J., B. Haverkort and W. Hiemstra (Eds.). London, pp: 52-79.
[2] Alexopoulos, C.O., Mims, C.W. and Blackwell, M. (2002). Introductory Mycology. 4th ed. John Wiley and Sons Inc. Singapore.
869pp.
[3] Amadioha, A.C (2000). Fungitoxic effects of some leaf extracts against Rhizopus oryzae causing tuber rot of potato. Archives of
Phytopatholpflanzo 34:1-9.
[4] Amadioha, A.C and Obi, V.I (1999). Control of Anthranose diseases of Cowpea by Cymbopogon cunitus and Ocimum
gratissimum. Acto Phytopathology and Entomology 85: 89.
[5] Barnett, H.L. and Hunter, B.B. (1999). Illustrated Genera of Imperfect Fungi, 4th ed. The American Phytopathological Society . St.
Paul, Minnessota,USA, 218pp.
[6] Chiejina, N.V and Ukeh, J.A (2012). Antimicrobial properties and phytochemical analysis of methanolic extracts of Afrmomum
melegueta and Zingiber officinale on fungal diseases of tomato fruit. Journal of Natural Sciences Research 2(6):10-15.
[7] Chuku, E.C, Osakwe, J.A and Daddy-West, C. (2010). Fungal spoilage of tomato (Lycopersicon esculentum Mill), using garlic and
ginger. Scientia Africana, 9(2): 42-50.
[8] Ilondu, E.M., B.O. Ejechi and J.A. Souzey, (2001). Microbial stability of jam prepared from velvet tamarind and preserved by
combined processes. Nigerian Journal of Microbiology, 5: 93-96.
[9] Janardhana, G.R., Raveesha, K.A. and Shetty, H.S. (1999). Mycotoxin contamination of maize grains grown in Karnataka (India).
Food Chemical Toxicology 37: 863 – 868.
[10] Lattanzio, V. (2003). Bioactive polyphenols: their role in quality and storability of fruit and vegetables. Journal of Applied Botany.
77, 128–146.

1] Alam,S.,G.Kabir,M.N. Amin and M.Islam.1987.Mitotic effect of leaf extract of Ipomoea carnea on Allium cepa. Cytologia,
52:721-724.
[2] Babich,H.,M.A.Segall,K.D.Fox.1997.The Allium test-Asimple ,eukaryote genotoxicity assay .Am Biol Teach., 59:580-583
[3] Badr,A., A. Ghareeb and H.M.El-Din.1992.Cytotoxicity of some pesticides in mitotic cells of Viciafaba roots,Egypt.J.Appl.Sci.7:457-468.
[4] Dubinin,N. P. and V.K.Scerbako.1962.Control of the natural mutation process by means of cysteamine and
streptomycin.Proc.Acad.Sci.USSR,145:427-429.
[5] Duk ,S.O.1990 :Natural pesticides from plants. Advances in new crops.Timber Press,Portland,OR.P:511-517.
[6] Kabarity,A.,G.Malallah.1980.Mito-depressive effect of kont extracts in the meristematic region of Allium cepa root tips.Cytologia.
45(4):730-733.
[7] Kaushik,G.C.1996.Cytologcal effects of Lantana cameral L. leaf extract on Viciafaba root tip cells.AD.Plant Sci.9(2):159-164.
[8] Koul,A., S.C.Gangar, and V.Sandhir .2005.Pitfalls in journey from traditional to modern medicine.Natural Product Radiance
Sin.,24:7-21.
[9] Kovach,J.,C.Petzoldt,J.Degnil, and J.Tette,1992. Amethod To Measure TheEnvironmental Impact of Pesticides. IPM Program
Cornell University.New York State Agricultural Experiment Station Geneva, NewYork 14456 (Cornell Cooperative
Extension,Lewis County, Lowville,NewYork13367.
[10] Krivokapic,K.,R.Hadziselimovic, A.Sofradzija.1970.Effect of extract from immature fruits of Solanumnigrum on the intensity of
mitosis in Allium sativum.Iugosl.Physiol.Pharmacol.Acta, 6:363-367.

[1] K. J. McDowall, A Thamchaipenet and IS. Hunter. Phosphate Control of Oxytetracycline Production by Streptomyces rimosus Is at the Level of Transcription from Promoters Overlapped by Tandem Repeats Similar to Those of the DNA-Binding Sites of the OmpR
Family, J. Bacteriol. 181(10), 1999, 3025-3032.
[2] I. Chopra and T. G .B. Howe, Bacterial Resistance to the Tetracyclines, American Society for Microbiology, 42(4), 1978,707-724.
[3] H. Petkovic, J. Cullum, D, Hranueli, I. S. Hunter, Genetics of Streptomyces rimosus, the Oxytetracycline Producer, Microbiology and Molecular Biology Reviews, 70(3), 2006, 3704-728.
[4] BL. zheng and JP. qiu, Genome Shuffling in the development of new application of metabolites, china biotechnology, 32(3), 2012,
100-105.
[5] B. Otte, E. Grunwaldt, O. Mahmoud and S. Jennewein, Genome Shuffling in Clostridium diolis DSM 15410 for Improved
1,3-Propanediol Production, Environ. Microbiol, 75(24), 2009, 7610-7616.
[6] Y. X. Zhang, K. Perry, VA. vincl, K. Powell, Genome shuffling leads to rapid phenotypic improvement in bacteria, nature, 415(7),
2002, 644-646.
[7] J. Pigac, D. Hranueli, T. Smokvina, Optimal Cultural and Physiological Conditions for Handling Streptomyces rimosus Protoplasts,
Applied And Environment Microbiology, 44(5), 1982, 1178-1186.
[8] ZH. Jin, B. Xu, SZ. Lin, QC. Jin, PL. Cen, Enhanced Production of Spinosad in Saccharopolyspora spinosa by Genome Shuffling,
Biochemical Biotechnology, 159, 2009, 655–663.
[9] H. Hida, T. Yamada, Y. Yamada, Genome shuffling of Streptomyces sp. U121 for improved production of hydroxycitric acid, Appl
Microbiol Biotechnol, 73, 2007, 1387-1393.
[10] SH. SH. Yang, CH. M. Lee, Effect of culture media on protease and oxytetracycline production with mycelium and protoplasts of
Streptomyces rimosus,World Journal of Microbiology＆Biotechnology, 17, 2001, 403-410.

[1] J.A. Akpala, R.O. Bolaji, Adolescents and Psychosocial Problems. Lagos, Nigeria: Longman, 1991
[2] S. Das, V.K. Alagappan, D. Bagchi, H.S. Sharma, N. Maulik, D.K. Das, Coordinated induction of iNOS-VEGF-KDR-eNOS after
resveratrol consumption: A potential mechanism for resveratrol preconditioning of the heart. Vascul. Pharmacol. 2005, 42, 281-289.
[3] D. Seth, P.J. Hogg, M.D. Gorrell, G.W. McCaughan, P.S. Haber, P.S. Direct effects of alcohol on hepatic fibrinolytic balance:
Implications for alcoholic liver disease. Journal of Hepatology 2008, 48: 614-627.
[4] B.F.Grant, F.S.Stinson, T.C. Harford, Age at onset of alcohol use and DSM-IV alcohol abuse and dependence: A 12-year follow-up.
Journal of Substance Abuse; 2001.13: 493-504.
[5] A. George, V.M. Figueredo, Alcohol and arrhythmias: A comprehensive review. Journal of Cardiovacular Medicine. (Hagerstown)
2010; 11: 221-228.
[6] V. Marinho, J. Laks, E. Engelhardt, D. Conn, Alcohol abuse in an elderly woman taking donepezil for Alzheimer disease. Journal
of Clinical Psychopharmacology, 2006; 26: 683-685.
[7] A.I. Cederbaum, Y. Lu, D. Wu, Role of oxidative stress in alcohol-induced liver injury. Archives of Toxicology. 2009; 83: 519-548.
[8] D.O. Baliunas, B.J.Taylor, H. Irving, M. Roerecke, J. Patra, S. Mohapatra, J. Rehm, Alcohol as a risk factor for type 2 diabetes: A
systematic review2009.
[9] J. Haoraha, S.H. Ramirez, N. Floreani, S. Gorantla, B. Morsey, Y. Persidsky, Mechanism of alcohol -induced oxidative stress and
neuronal injury. Free Radic Biol Med 2008; 45(11): 1542-1550.
[10] D.M. Melissa, Y.A. Michael, J.K. Sandra, Vitamin E protects against alcohol-induced cell loss and oxidative stress in the neonatal
rat hippocampus International Journal of Developmental Neuroscience 2004, 22: 363–377

[1] Kibria, G. and Ahmed, K. K. U., 2005. Diversity of selective and nonselective fishing gear and their impact on inland fisheries in
Bangladesh. NAGA, 28,43-48.
[2] Craig, J. M.; Halls, A. S.; Barr, J. J. F.; Bean, C. W., 2004. The Bangladesh floodplain fisheries. Fish. Res., 66, 271–286.
[3] Hamiton, F. 1822. An account of the fishes found in the river Ganges and its branches. Archibald constable and company.
Edinburg. Vill.405 pp.
[4] Mirza, M.R. 2002.Checklist of freshwater fishes of Pakistan. Department of Zoology, Government College University, Lahore,
Pakistan.
[5] Rahman, A.K.A. 2005. Freshwater fishes of Bangladesh. Zoll. Soc. of Bangladesh, pp.304-52.
[6] Moutopoulos, D. K.; Stergiou, K. I., 2002. Length-weight and lengthlength relationships of fish species from Aegean Sea (Greece).
J. Appl. Ichthyol,. 18, 200–203.
[7] Martin-Smith, K.M. 1996. Length/weight relationships of fishes in a diverse tropical fresh-water community, Sabah, Malaysia.
Journal of Fish Biology, 49, 731-734.
[8] Ecoutin, J. M.; Albaret, J. J.; Trape, S., 2005. Length-weight relationships for fish populations of a relatively undistributed tropical
estuary: the Gambia. Fish. Res. 72, 347–351.
[9] Bagenal, T. B. and Tesch, F. W., 1978. Age and growth. In: Methods for assessment of fish production in fresh waters, 3rd edn. T.
Begenal (Ed.). IBP Handbook No. 3, Blackwell Science Publications,Oxford, pp. 101–136.
[10] Petrakis, G.; Stergiou, K. I., 1995. Weight-length relationships for 33 fish species in Greek waters. Fish. Res. 21, 465–469.

[1] T. Foster and D. Mcdevitt. Surface associated proteins of Staphylococcus aureus: their possible role in virulence, FEMS Microbiol.
Lett. 1994; 118: 199-205.
[2] K. Hiramatsu, H. Hanaki, T. Ino, K. Yabuta, T. Oguri, F. Tenover. Methicillin-Resistant Staphylococcus aureus clinical strain with
reduced vancomycin susceptibility. J ANTIMICROB CHEMOTHER. 1997, JUL; 40(1):135-6.
[3] Y. Katayama, T. Ito, K. Hiramatsu. A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin
resistance in Staphylococcus aureus. Antimicrob Agents Chemother. 2000 Jun; 44(6):1549-55.
[4] F. Lowy. Antimicrobial resistance: The example of Staphylococcus aureus. J Clin Invest. 2003; 111(9): 1265–1273.
[5] H. Momtaz, E. Rahimi, and E. Tajbakhsh. Detection of some virulence factors in Staphylococcus aureus isolated from clinical and
subclinical bovine mastitis in Iran. African Journal of Biotechnology Vol. 9(25), pp. 3753-3758, 21 June, 2010
[6] Bauer, W. Kirby, J. Sherris. Antibiotic susceptibility testing by a standardized single disc method. Am. J. Clin. Pathol. 996; 45:493-
496
[7] F. Espersen. Identifying the patient risk for Staphylococcus aureus blood stream infections. J. Chemotherapy, 1995 7: 11-17.
[8] H. Delancastre, I. Santos, and I. Sanches. Streptococcus pneumoniae: molecular biology and mechanisms of disease. Clinical
Microbiology and Molecular Microbiology in alliance CEM/NET. Mary Ann Liebert, Inc., Larchmont, New York, U.S.A. 2000; 451-
456.
[9] A.Gales, R. Jones, and M. Pfaller,. Two year assessment of pathogen frequency and antimicrobial resistance pattern among
organisms isolated from skin and soft tissue infection in Latin American hospitals: results from the sentry antimicrobial surveillance
program, 1997-1998. Int. J. Infect. Dis., 2000; 4: 7-84.
[10] S. Raquel, I. Sanches, and D. Dias. Detection of an Archaic Clone of Staphylococcus aureus with Low-Level Resistance to
Methicillin in a Pediatric Hospital in Portugal and in International Samples: Relics of a Formerly Widely Disseminated Strain.
Journal of Clinical Microbiology, 1999; 37 (6): 1913-1920.

[1] Russell, R. R. B. (2000). Pathogenesis of oral streptococci. In: Gram-positive pathogens. Fischetti VA, Novick RP, Ferretti JJ,
Portnoy DA, Rood JI, eds. ASM Press: Washington, DC; pp. 272-279.
[2] Monchois, V.; Willemot, R. M. and Monsan, P. (1999). Glucansucrases: mechanism of action and structure-function relationships.
FEMS Microbiol. Rev. 23: 131-151.
[3] Al-Jumaily,E.F.A.; Al-Mudallal, N.H.A.; Muhimen,N.A.A. and Al-Shaibany, A.A. (2009). Eavluation of matans streptococci local
strains for production of glucosyltransferase enzyme. The 2 nd Kurdistan Conference on Biological Sciences. J. Duhok Univ.
Vol.12 No.1 (Special Issue)Pp. 44-48.
[4] Bowen, W.H and Koo, H. (2011). Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix
formation of cariogenic biofilms. Caries Res. 45(1):69-86. Epub .
[5] Jespersagaard, C.; Hajishengallis, G.; Hung, Y. and Michalek, S. (2000). Protective immunity against Streptococcus mutans
infection in mice after intranasal immunization with glucan-binding region of Streptococcus mutans. Infe. Immun. 67(12): 6543-9.
[6] Al-Mudallal N. H. A (2006). Characterization of Glucosyltransferase of Mutans Streptococci Streptococcus sobrinus (Serotype G)
(Functional and Immunological Assessment). Ph.D thesis, Biotechnology Department, College of Science, Al-Nahrain University.
[7] Al-Mudallal N. H. A. ;. Al-Jumaily E. F. A ;.Al.- Muhimen N. A. and Abd Al-wahid Al-Shaibany (2008). Isolation And
Identification of Mutans streptococci Bacteria From Human Dental Plaque.Journal of .Al-Nahrain Univ.Science. 11(3):98-105.
[8] Al-Mudallal N. H. A. ; Al-Jumaily E. F. A ;.Al.- Muhimen N. A. and Abd Al-wahid Al-Shaibany (2011). Isolation and
Purification of Glucosyltransferase from mutans streptococci Streptococcus sobrinus serotype G local isolate. Iraqi Journal of
Medical Science.7:5-10.
[9] 9. Wunder, D. E. and Bowen, W. H. (2000). Effects of antibodies to glucosyltransferase on soluble and insolubilized enzymes.
Oral Diseases. 6: 289-296.
[10] Evans, R. T. and Genco, R. J. (1973). Inhibition of glucosyltransferase activity by antisera to known serotypes of Streptococcus
mutans. Infect. Immun. 7(2): 237-241

[1] Adedapo AA, Abatan MO, Olorunsogo OO (2007): Effects of some plants of the spurge family on haematological and biochemical
parameters in rats. VETERINARSKI ARHIV 77 (1), 29 – 38.
[2] Adewusi EA, Afolayan AJ (2009): Safety evaluation of the extract from the roots of Pelargonium reniforme Curtis in male wistar
rats. Afr. J. Pharm and Pharmacology, vol. 3(8): pp. 368 – 373.
[3] Ajarem JS (1990): Effect of fresh kola-nut extract (Cola nitida) on the locomotor activities of male mice. Acta Physiol. Pharmacol.
Bulg. (16) pp 10 – 15.
[4] Biu AA, Yusufu SD, Rabo JS (2009): Studies on the effects of aqueous leaf extracts of Neem (Azadirachta indica) on
haematological parameters in chicken. African scientist Vol. 10 No 4 pp 189 – 192.
[5] Dacie JV, Lewis SM (1991): Practical haematology, 7th edition ELBS with Churchill Livingston, England, pp 37-85.
[6] Doumas BT, Watson W, Biggs HC (1971): Albumin standards and the measurement of serum albumin with bromocresol green.
Clinica Chimica Acta 31, 87-96.
[7] Duncan JR, Praise KW, Mahaffey EA (1994): Veterinary Laboratory Medicine (Clinical Pathology) 3rd ed. Iowa State University
Press, U.S.A.
[8] Hatasaka H, Goldstain M (2001): Kola nut as a symbol and its effect on the central nervous system. J. sep. 25: 257 (5): 2133 – 2136.
[9] Jain NC (1986): Schalm's Veterinary Haematology 4th ed. Lea and Fabiger, Philadelphia.
[10] Mitruka BM, Rawnsley H (1977): Clinical, biochemical and haematological references values in normal experimental animals.
Masson Publishing USA Inc. Pp. 53-54.

[1] Baldessarini RJ (1980): In drugs and the treatment of psychiatriod disorders. The pharmacological basis of therapeutics Ed. By
Goodman and Gilman. Macmillan Pub. Co. Inc. pp. 301-417.
[2] Bloom W, Fawcett DW (1975): Male reproductive system. In the textbook of Histology. Saunders Company, Philadelphia.
[3] Bowman WC, Rand MJ (1985): The reproductive system and drugs affecting the reproductive systems. Textbook of pharmacology,
2nd edition, 20:1-8.
[4] Christensen AC (1975): Leydig cell: In: Handbook of Physiology, edited by P.O. Greep and E.B. Astwoods. Washington D C
American Physiological Society.
[5] Das UK, De D, Chatterjee K, Mallick C, Bera TK, Ghosh D (2009): Antigonadal effect induced by hydro-methanolic extract of leaf
of Aelgle mermelos in male rat: Effect of hCG co-administration. Journal of Medicinal Plants Research Vol. 3(10), Pp728 – 735.
[6] Gaciong Z (2003): The real dimension of analgesic activity of aspirin. Thrombosis Research 110(5-6): 361 – 4
[7] Gonzales C, Rubio J, Gasco M, Nieto J, Sandra Y, Gonzales GF (2006): Effect of short -term and long-term treatments with three
ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats. Journal of Ethnnopharmacol. (103), 448 – 454.
[8] Krishnamoorthy P, Viathinathan S, Rani V, Bhuvaneswari A (2007): Effect of Terminalia chebula fruit extract on lipid
peroxidation and antioxidative system of testis of albino rats. African Jouranl of Biotechnology, Vol. 6 (16), Pp 1888 – 1891.
[9] Laing JA (1979): Fertility and infertility in domestic animals. 3rd edition 1979 Bailliere Tindall, a division of Cassell Lt.
[10] Lewis HD, Davis JW, Archibald DG, steinkes WF, Smitherman TC, Doherty JE (1983): Protective effect of aspirin against acute
myocardial and death in men with unstable angina. New England Journal of Medicine 309 (7): 396 – 403.

[1] Adedapo AA, Abatan MO, Olorunsogo OO (2007): Effects of some plants of the spurge family on haematological and biochemical
parameters in rats. VETERINARSKI ARHIV 77 (1), 29 – 38.
[2] Adewusi EA, Afolayan AJ (2009): Safety evaluation of the extract from the roots of Pelargonium reniforme Curtis in male wistar
rats. Afr. J. Pharm and Pharmacology, vol. 3(8): pp. 368 – 373.
[3] Biu AA, Yusufu SD, Rabo JS (2009): Studies on the effects of aqueous leaf extracts of Neem Azadirachta indica on haematological
parameters in chicken. African scientist Vol. 10 No 4 pp 189 – 192.
[4] Carlsson S et al (2003): Alcohol consumption and the incidence of type 2 diabetis: a 20-year follow–up of the Finish Twin Cohort
Study. Diabetis care 26(10): 2785 – 2786.
[5] Dacie JV, Lewis SM (1991): Practical haematology, 7th edition ELBS with Churchill Livingston, England, pp 37-85.
[6] De Wood MA, Spores J, Mouser LT, Burroughs R, Golden MS, Lang HT (1980): Prevalence of total coronary occlusion during the
early hours of transmural myocardial infarction. N.Engl. J. Med. 303: 897 – 902.
[7] Dees WL, Dissen GA, Hiney JK (2000): Alcohol ingestion inhibits the increased secretion of puberty-related hormones in the
developing female Rhesus monkey. Endocrinology 141: 1325 – 1331.
[8] Doumas BT, Watson W, Biggs HC (1971): Albumin standards and the measurement of serum albumin with bromocresol green.
Clinica Chimica Acta 31, 87-96.
[9] Duncan JR, Praise KW, Mahaffey EA (1994): Veterinary Laboratory Medicine (Clinical Pathology) 3rd ed. Iowa State University
Press, U.S.A.
[10] Froehlich JC (1993): Interactions between alcohol and the endogenous opoid system. National Institute on Alcohol Abuse and
Alcoholism Research Monograph No 23. NIH Pub. No. 93 – 3533. Bethesda, MD: National Institutes of Health, pp. 21 – 35.

[1] Baldessarini RJ (1980): In drugs and the treatment of psychiatriod disorders. The pharmacological basis of therapeutics Ed. By
Goodman and Gilman. Macmillan Pub. Co. Inc. pp. 301-417.
[2] Bloom W, Fawcett DW (1975): Male reproductive system. In the textbook of Histology. Saunders Company, Philadelphia.
[3] Bowman WC, Rand MJ (1985): The reproductive system and drugs affecting the reproductive systems. Textbook of pharmacology,
2nd edition, 20:1-8.
[4] Christensen AC (1975): Leydig cell: In: Handbook of Physiology, edited by P.O. Greep and E.B. Astwoods. Washington D C
American Physiological Society.
[5] Das UK, De D, Chatterjee K, Mallick C, Bera TK, Ghosh D (2009): Antigonadal effect induced by hydro-methanolic extract of leaf
of Aelgle mermelos in male rat: Effect of hCG co-administration. Journal of Medicinal Plants Research Vol. 3(10), Pp728 – 735.
[6] Eluwa MA, Agarrey LE, Ekanem TB, Amabe OA, Agnes OE, Ekong MB (2010): Comparative study of teratogenic effects of
brewed beer and palm wine on fetal femur bone of albino Wistar rats. Int. J. Biomed. And Health Sci. Vol., 6, No 4 pp 229 – 233.
[7] Gonzales C, Rubio J, Gasco M, Nieto J, Sandra Y, Gonzales GF (2006): Effect of short-term and long-term treatments with three
ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats. Journal of Ethnnopharmacol. (103), 448 – 454.
[8] Krishnamoorthy P, Viathinathan S, Rani V, Bhuvaneswari A (2007): Effect of Terminalia chebula fruit extract on lipid
peroxidation and antioxidative system of testis of albino rats. African Journal of Biotechnology, Vol. 6 (16), Pp 1888 – 1891.
[9] Kumar, Abbas, Fausto (1999): Pathology Bases of Disease, 7th edition, China: Elsevier Saunders, 122.
[10] Laing JA (1979): Fertility and infertility in domestic animals. 3rd edition 1979 Bailliere Tindall, a division of Cassell Lt.

[1] Adedapo AA, Abatan MO, Olorunsogo OO (2007): Effects of some plants of the spurge family on haematological and biochemical
parameters in rats. VETERINARSKI ARHIV 77 (1), 29 – 38.
[2] Anderson BJ, Hollford NHG, Woolard GA (1998): Paracetamol plasma and cerebrospinal fluid pharmacokinetics in children. Br J
Clin Pharmacol; 46 : 237 – 43
[3] Baldessarini RJ (1980): In drugs and the treatment of psychiatriod disorders. The pharmacological basis of therapeutics Ed. By
Goodman and Gilman. Macmillan Pub. Co. Inc. pp. 301-417.
[4] Biu AA, Yusufu SD, Rabo JS (2009): Studies on the effects of aqueous leaf extracts of Neem Azadirachta indica on haematological
parameters in chicken. African scientist Vol. 10 No 4 pp 189 – 192.
[5] Bloom W, Fawcett DW (1975): Male reproductive system. In the textbook of Histology. Saunders Company, Philadelphia.
[6] Bowman WC, Rand MJ (1985): The reproductive system and drugs affecting the reproductive systems. Textbook of pharmacology,
2nd edition, 20:1-8.
[7] Cramer DW, Harlow BL, Titus-Ernstoff L, Bohike K, Welch WR, Greenberg ER (1998): Over- the-counter analgesics and risk of
ovarian cancer. Lancet, 351: 104 – 7.
[8] Dacie JV, Lewis SM (1991): Practical haematology, 7th edition ELBS with Churchill Livingston, England, pp 37-85.
[9] Daly FF, Fountain JS, Murray L, Graudins A, Buckley NA (2008): "Guidelines for the management of paracetamol poisoning in
Australia and New Zealand – explanation and elaboration. A consensus statement from clinical toxicologists consulting to the
Australasian poisons information centres". Med. J. Aust. 188(5): 296 – 301.
[10] Daniel EI, Clement ON (2008): Effect of ethanolic extract of Dennettia tripetala fruit on haematological parameters in albino Wista
rats. Nigeria Journal of Physiological Sciences 23(1-2):13-17.

[1] Ainslie JR (1937): The list of plants used in native medicine in Nigeria, Imp. Forest. Inst. Oxford Inst. Paper 7(mimeo).
[2] Baldessarini RJ (1980): In drugs and the treatment of psychiatriod disorders. The pharmacological basis of therapeutics Ed. By
Goodman and Gilman. Macmillan Pub. Co. Inc. pp. 301-417.
[3] Bloom W, Fawcett DW (1975): Male reproductive system. In the textbook of Histology. Saunders Company, Philadelphia.
[4] Bowman WC, Rand MJ (1985): The reproductive system and drugs affecting the reproductive systems. Textbook of pharmacology,
2nd edition, 20:1-8.
[5] Burkill HM (1997): The useful plants of West Tropical Africa, vol.4. The Whitefriars Press Limited, Tonbridge, Kent TN9 IQR,
Great Britain.
[6] Christensen AC (1975): Leydig cell: In: Handbook of Physiology, edited by P.O. Greep and E.B. Astwoods. Washington D C
American Physiological Society.
[7] Das UK, De D, Chatterjee K, Mallick C, Bera TK, Ghosh D (2009): Antigonadal effect induced by hydro-methanolic extract of leaf
of Aelgle mermelos in male rat: Effect of hCG co-administration. Journal of Medicinal Plants Research Vol. 3(10), Pp728 – 735.
[8] Gonzales C, Rubio J, Gasco M, Nieto J, Sandra Y, Gonzales GF (2006): Effect of short-term and long-term treatments with three
ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats. Journal of Ethnnopharmacol. (103), 448 – 454.
[9] Gupta RS, Kumar P, Dixit VP, Dobhal MP (2000): Antifertiliy studies of the root extract of the Barleria prionitis in male albino
rats with special reference to testicular cell population dynamics. J Ethnopharmacol 2000; 70:111-17.
[10] Gupta RS, Yadav R, Dixit VP, Dobhal MP (2001): Antifertility studies of Colebrookia oppositifolia leaf extract in male rats with
special reference to testicular cell population dynamics. Fitoterapia 72(3): 236-45.