Series-1 (Jul. – Aug. 2024) Jul. – Aug. 2024 Issue Statistics
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Abstract: Fermented bean curd is a traditional Chinese fermented food, usually used as an appetizer, side dish, or condiment. During fermentation, compounds such as soybean proteins and fats are hydrolyzed by microbial action to form flavor substances. At the same time, microorganisms are also essential for the food safety of fermented bean curd. In order to comprehensively understand the characteristics and research progress of fermented bean....
Keywords: fermented bean curd; classification; fermentation strains; flavor substances
[1] Tziva M, Negro S O, Kalfagianni A, Et Al. Understanding The Protein Transition: The Rise Of Plant-Based Meat Substitutes[J]. Environmental Innovation And Societal Transitions, 2020, 35: 217-231.
[2] Wei G, Chitrakar B, Regenstein J M, Et Al. Microbiology, Flavor Formation, And Bioactivity Of Fermented Soybean Curd (Furu): A Review[J]. Food Research International, 2023, 163: 112183.
[3] Hwan C H, Chou C C. Volatile Components Of The Chinese Fermented Soya Bean Curd As Affected By The Addition Of Ethanol In Ageing Solution[J]. Journal Of The Science Of Food And Agriculture, 1999, 79(2): 243-248.
[4] Lin Q, Sirisansaneeyakul S, Wang Q, Et Al. Yunnan Fermented Bean Curds: Furu (Lufu)[J]. Modernization Of Traditional Food Processes And Products, 2016: 125-144.
[5] Li Y Y, Yu R C, Chou C C. Some Biochemical And Physical Changes During The Preparation Of The Enzyme-Ripening Sufu, A.
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Abstract: Aloe has long been valued for its medicinal properties, particularly its anti-inflammatory, antioxidant, and immunomodulatory effects. Despite its widespread application in cosmetics, dietary supplements, and pharmaceuticals, concerns regarding the genetic stability of aloe extract components require thorough scientific evaluation. This study aimed to investigate the genotoxic potential of a complex aloe extract containing quercetin and aloesin. Utilizing the reverse mutation test on specific bacterial strains (Salmonella typhimurium and Escherichia coli) and the chromosomal aberration test on Chinese hamster lung fibroblasts (CHL/IU cells), we assessed...
Keywords: Aloe extract, Genotoxcity, chromosomal stabiliy, mutagenicity,safety
[1].
Sánchez, Marta ; González-Burgos, Elena ; Iglesias, Irene ; Gómez-Serranillos, M. Pilar, Pharmacological Update Properties Of Aloe Vera And Its Major Active Constituents, Molecules (Basel, Switzerland), 2020-03, Vol.25 (6), P.1324, Article 1324
[2].
Darzi, Saeedeh ; Paul, Kallyanashis ; Leitan, Shanilka ; Werkmeister, Jerome A. ;
Mukherjee, Shayanti, Immunobiology And Application Of Aloe Vera‐Based Scaffolds In Tissue Engineering, International Journal Of Molecular Sciences, 2021-02, Vol.22 (4), P.1-19, Article 1708
[3].
Mariana Chelu , Adina Magdalena Musuc , Monica Popa And Jose Calderon Moreno, Aloe Vera-Based Hydrogels For Wound Healing: Properties And Therapeutic Effects, Gels 2023, 9(7), 539
[4].
Kloosterman, Wigard P. ; Hochstenbach, Ron, Deciphering The Pathogenic Consequences Of Chromosomal Aberrations In Human Genetic Disease, Molecular Cytogenetics, 2014-12, Vol.7 (1), P.100-100, Article 100
[5].
Yakkala, Lakshmi Madhuri ; Somanjeri, Nithya ; Begum, Shaheen, A Validated Stability-Indicating Rp-Hplc Method For The Simultaneous Estimation Of Aloe Emodin, Aloin, And Emodin In A Marketed Formulation Of Aloe Vera, Journal Of Analytical Chemistry (New York, N.Y.), 2024, Vol.79 (6), P.808-812
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| Paper Type | : | Research Paper |
| Title | : | CRISPR-Cas9 In Cancer Therapy: Applications, Challenges, And Future Directions |
| Country | : | Canada |
| Authors | : | Jahnavi Dalmia |
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: | 10.9790/ 264X-1004012031 ![]() |
Abstract: CRISPR-Cas9 technology provides novel and revolutionary strategies for cancer therapy through accurate genome editing to target the intervention in malignancies. Here, we review the wide varieties of applications for CRISPR/Cas9 in cancer to disrupt oncogenes with clear examples and thorough discussion on improving immunotherapies as well as presenting more advanced modeling systems using CRISPR allowing new personalized....
Keywords: CRISPR-Cas9, Drug resistance, Cancer therapy, Genome editing, Immunotherapy.
[1] Katti, A.; Diaz, B.J.; Caragine, C.M.; Sanjana, N.E.; Dow, L.E. Crispr In Cancer Biology And Therapy. Nat. Rev. Cancer 2022, 22, 259–279.
[2] Feng, J.; Lu, H.; Ma, W.; Tian, W.; Lu, Z.; Yang, H.; Cai, Y.; Cai, P.; Sun, Y.; Zhou, Z.; Et Al. Genome-Wide Crispr Screen Identifies Synthetic Lethality Between Dock1 Inhibition And Metformin In Liver Cancer. Protein Cell 2022, 13, 825–841.
[3] Zou, Y.; Zheng, S.; Xie, X.; Ye, F.; Hu, X.; Tian, Z.; Yan, S.M.; Yang, L.; Kong, Y.; Tang, Y.; Et Al. N6-Methyladenosine Regulated Fgfr4 Attenuates Ferroptotic Cell Death In Recalcitrant Her2-Positive Breast Cancer. Nat. Commun. 2022, 13, 2672.
[4] Wan, C.; Mahara, S.; Sun, C.; Doan, A.; Chua, H.K.; Xu, D.; Bian, J.; Li, Y.; Zhu, D.; Sooraj, D.; Et Al. Genome-Scale Crispr-Cas9 Screen Of Wnt/Β-Catenin Signaling Identifies Therapeutic Targets For Colorectal Cancer. Sci. Adv. 2021, 7, Eabf2567.
[5] Pan, J.; Zhang, M.; Dong, L.; Ji, S.; Zhang, J.; Zhang, S.; Lin, Y.; Wang, X.; Ding, Z.; Qiu, S.; Et Al. Genome-Scale Crispr Screen Identifies Laptm5 Driving Lenvatinib Resistance In Hepatocellular Carcinoma. Autophagy 2023, 19, 1184–1198

