Series-1 (Mar. – Apr. 2026) Mar. – Apr. 2026 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Enhancing Clinical Trial Design With Decentralized, Patient-Centric Methods: Insights From A 2023 Product Discontinuation |
| Country | : | India |
| Authors | : | Bhanu Prakash Mettu |
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: | 10.9790/ 264X-1202010105  |
Abstract: Medical and product development greatly rely on the cornerstone of clinical trials. The outdated models, however, suffer from low patient reach, poor operating efficiency, and inadequate data quality. Efficiency and patient centrism are solutions to these barriers. In essence, the stop experience from 2023 should guide us towards more innovative thinking when it comes to trial design. In this article, I will concisely lay out some of the paradigm's established clinical trials' difficulty under the structure by discussing recruitment, data fragmentation, and retention rate issues......
Key Word: Clinical trial, medical product development, patient centric methods, decentralized clinical methods.
[1].
Craig Lipset, "Decentralized Clinical Trials: The Future Of Medical Research," Clinical Trials, Vol. 16, Pp. 1–6, 2019, January, Https://Doi.Org/10.1177/1740774518822552
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Eric J. Topol, "The Patient Will See You Now: The Future Of Medicine Is In Your Hands," The Lancet, Vol. 385, Pp. 482–483, 2015, February, Https://Doi.Org/10.1016/S0140-6736(15)60102-5
[3].
Kenneth Getz, "Improving Patient Engagement In Clinical Trials," Applied Clinical Trials, Vol. 27, Pp. 18–24, 2018, March, Https://Www.Appliedclinicaltrialsonline.Com/View/Improving-Patient-Engagement-Clinical-Trials
[4].
Annick Anderson, "Remote Trials: Bridging The Gap Between Patients And Research," Journal Of Clinical Research Best Practices, Vol. 14, Pp. 1–7, 2018, June, Https://Www.Jclinicalresearch.Com/Remote-Trials-Bridging-Gap
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| Paper Type | : | Research Paper |
| Title | : | Prevalence And Molecular Charaterization Of Multiple Resistance Genes Associated With Escherichia Coli Isolated From Poultry Farms In Abakaliki Metropolis Ebonyi State |
| Country | : | |
| Authors | : | J. O Ikporo || A.C Nwuzo || O. E Udu-Ibiam || O. C Ote || M. I, Ogwa |
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: | 10.9790/ 264X-1202010611 |
Abstract: This study was conducted to determine the prevalence of multiple resistance genes associated with Escherichia coli from poultry farms in Abakaliki me-tropolis, Ebonyi State, Nigeria. A total of 500 poultry samples were collected from poultry samples as follows: cloacal n=125, feed n=125, water n=125 and meat n=125 and analyzed in the Microbiology Laboratory Complex of Ebonyi State University using microbiological standard. The E. coli isolates were identified by morphology, culture and biochemical tests and further subjected to antimicrobial....
Key Word: Antimicrobial resistance markers, poultry, bacterial resistance, Antibacterial susceptibility, Inhibition zones.
[1].
Aarestrup, F. M., Lertworapreecha, M., Evans, M. C., Bangtrakulnonth, A., Chalermchaikit, T., Hendriksen, R. S., Wegener, H. C (2013). Antimicrobial Susceptibility And Occurrence Of Resistance Genes Among Salmonella Enterica Serovar Weltevreden From Different Countries. Journal Of Antimicrobial. Chemotherapy, 23(52):715–718.
[2].
Abbassi-Ghozzi, I., Jaouani, A., Hammami, S., Martinez-Urtaza, J., Boudabous, A And Gtari, M (2015). Molecular Analysis And Antimicrobial Resistance Of Salmonella Isolates Recovered From Raw Meat Marketed In The Area Of Grand Tunisia. Pathology Biology, 10(8):13 -17.
[3].
Abd El-Aziz, N. K., Tartor, Y. H., Gharieb, R. M. A., Erfan, A. M., Khalifa, E., Said, M. A., Ammar, A. M And Samir, M (2021). Extensive Drug-Resistant Salmonella Enterica Isolated From Poultry And Humans: Prevalence And Molecular Determinants Behind The Co-Resistance To Ciprofloxacin And Tetracycline. Front Microbiology, 12: 738784.
[4].
Abdallah, H. M (2011). Extended-Spectrum Beta-Lactamases And/Or Carbapen Emases-Producing Enterobacteriaceae Isolated From Retail Chicken Meat In Zagazig, Egypt Epidemiology Of Infection, 14(4): 997–1005.
[5].
Brower, C. H., Mandal, S., Hayer, S., Sran, M., Zehra, A And Patel, S. J (2017). The Prevalence Of Extended-Spectrum Beta-Lactamase-Producing Multidrug-Resistant Escherichia Coli In Poultry Chickens And Variation According To Farming Practices In Punjab, India Environmental Health Perspect. 125: 077015.
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| Paper Type | : | Research Paper |
| Title | : | Statistical Analysis of Nundkol Lake Water |
| Country | : | India |
| Authors | : | Dr.Meenakshi Sharma || VinayKhandelwal |
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: | 10.9790/ 264X-1202010615 |
Abstract: This study investigates the physicochemical parameters influencing the ecological health of Nundkol Lake, located in the Kashmir region, with a focus on identifying contamination sources, particularly during high-activity seasons. Water samples were collected from surface and groundwater sources across different seasons to capture seasonal variations in water quality. The physicochemical parameters analyzed included temperature, pH, dissolved oxygen, and water transparency, which were measured to assess the quality of the water. Statistical analysis, specifically....
Key Word: Water Quality, Nundkol Lake, Microbial Contamination, Antibiotic Resistance, Environmental Conservation
[1].
Aftab, Begum, S. Y, Noorjahan, C. M., Dawood, Sharif, S, (2005), Physico-chemical and fungal analysis of a fertilizer factory effluent, Nature Environment & Pollution Technology, 4(4), 529-531.
[2].
Akshay R. Thorvat, N P Sonaje, M M Mujumdar “Development of regression model for the Panchaganga River water quality in Kolhapur city” Engineering Research and Applications, 1(4), 2011, pp1723-1730.
[3].
APHA. Standard methods for the examination of water & wastewater. Port city press, Baltimore, Maryland, USA. Ed. 2001.
[4].
ASTM International, (2003), Annual Book of ASTM Standards, Water and Environmental Technologyv. 11.01, West Conshohocken, Pennsylvania, pp 6-7.
[5].
B. Banakar, B. R. Kiran, E.T. Puttaiah, R.Purushotham& S. Manjappa (2005), "Hydrochemical Characteristics Of Surface Water In Chandravalli Pond, Near Chitradurga".
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| Paper Type | : | Research Paper |
| Title | : | Integrated Multi-Omics And Biopython Approaches For Target Identification Of Α-Synuclein Polymorph In Parkinson's Disease |
| Country | : | India |
| Authors | : | Dhanashri Mandra || Uma Kumari || Neha Singh || Aashritha Marouthu |
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: | 10.9790/ 264X-1202011221 |
Abstract: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterised by the degeneration of dopaminergic neurons and the abnormal aggregation of α-synuclein protein within neuronal cells. The misfolding of α-synuclein leads to the formation of amyloid fibrils and Lewy bodies, which are considered major pathological hallmarks of the disease. Structural polymorphs of α-synuclein fibrils have been identified, among which the cryo-EM resolved polymorph...
Key Word: α-Synuclein, Parkinson’s disease, Amyloid polymorph, Bio Python, Contact map, Protein aggregation, Therapeutic Targeting
[1].
Association Of Synuclein Alpha (SNCA) Gene Polymorphisms With Spontaneous Brain Activity In Patients With Parkinson’s Disease - Pubmed. Https://Pubmed.Ncbi.Nlm.Nih.Gov/39281177/ (Accessed 2026-02-12).
[2].
Bank, R. P. D. RCSB PDB - 8H04: Major Polymorph In Alpha-Synuclein Fibril Seeded By Cerebrospinal Fluid From A Postmortal Parkinson’s Disease Patient. Https://Www.Rcsb.Org/Structure/8H04 (Accessed 2026-02-12).
[3].
KUMARI, U.; Pacholee, K. In-Silico Drug Discovery-Based Approach To Treat Impairments In Patients Of Alzheimer’s Disease. In JETIR; 2023; Vol. 10.
[4].
Kumari, U.; Pradhan, M.; Mukherjee, S.; Chakrabarti, S. NGS ANALYSIS APPROACH FOR NEURODEGENERATIVE DISEASE WITH BIOPYTHON. In JETIR; 2023; Vol. 10.
[5].
Singh, N.; Kumari, U. Mult-Omics-Based Drug Discovery Pipelines Incorporating Machine Learning, AI, And Biopython In Parkinson’s Disease: A Case Study Of 5A Polymorph Of Alpha-Synuclein. 2026, 13 (2)..