Series-1 (Jul. – Aug. 2022)Jul. – Aug. 2022 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Exploring the Effects of IL-1βcytokine gene polymorphism on HIV-1/AIDS infection |
| Country | : | Iraq |
| Authors | : | Salih Abdul Mahdi |
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: | 10.9790/264X-08040104  |
Abstract: The pro-inflammatory cytokine interleukin1β (IL-1β) gene is a member of the IL-1 gene family clustered on Chromosome 2.Several studies have reported that interleukin-1 ß enhanced HIV-1 replication, suggesting that this cytokine may be contributing to the pathogenesis and progression of HIV infection. Therefore, we aimedin this study to investigate the association between polymorphisms in the IL-1β(-511) and HIV-1/AIDS infection in North Indian population.Methods: Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) were used to analyze IL-1βC/T at (-511) polymorphism in 300 positively diagnosed cases with HIV-1/AIDS and an equal number of negatively diagnosed controls of the matched age.Results: No significant differences on the allelic and genotypicfrequencies were found among cases and control groups.Conclusions: The present study on the Indian population showed no significant association between IL-1βC/T (-511) polymorphism and the risk of HIV-1/AIDS infection.
Keywords: IL-1 β, Pro-inflammatory, Cytokine, polymorphism,RFLP, HIV-1/AIDS
[1]. Coffin J. (1996) HIV and viral dynamics. Presented at: 11th International Conference on AIDS. Vancouver, British Columbia .July 7-12.
[2]. Priscilla Y Hsue, Danny Li, Yifei Ma, AmorinaIshai, Maura Manion, Matthias Nahrendorf, Peter Ganz, Paul M Ridker, Steven G Deeks, Ahmed Tawakol. IL-1β Inhibition Reduces Atherosclerotic Inflammation in HIV Infection.(2018). J Am CollCardiol. 2018 Dec 4;72(22):2809-2811.
[3]. Marmor M., K. Hertzmark., S. M. Thomas., P. N. Halkitis., M. Vogler.(2016). Resistance to HIV Infection. Journal of Urban Health: Bulletin of the New York Academy of Medicine.V83, No. 1
[4]. Fowke KR., Nagelkerke NJ., Kimani J.(1996). Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya. Lancet. 348, 1347- 1351.
[5]. Kathy TriantafilouID, Christopher J. K. Ward , Magdalena CzubalaID, Robert G. Ferris, Emma Koppe1 , Curt HaffnerID , Vincent PiguetID, Vipulkumar K. PatelID , Heather Amrine-Madsen , Louise K. Modis1 , Seth L. MastersID, Martha TriantafilouID, (2021).Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages PLOS Pathogensjournal..
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| Paper Type | : | Research Paper |
| Title | : | Stored Grains Protection Activity of Ocimum Suave Extracts and Compounds on Larger Grain Borer |
| Country | : | Kenya |
| Authors | : | Sylvia A. Opiyo |
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: | 10.9790/264X-08040510 |
Abstract: Post-harvest pests cause serious losses to agricultural products in Africa. The pests consist mostly of beetles or moths and infest the grains at the crop stage or during the storage. Larger grain borer, Prostephanus truncatus (Horn), causes maize-grain losses during storage ranging from 30% to greater 40% of total production in 6 months. It reduces germination potential of maize grain and increases the grain's moisture content thus accelerating contamination by fungi and bacteria. The aim of this study was to determine the insecticidal extracts and compounds from Ocimum suave. Percentage mortality of the insects were recorded 1, 2, 14 and 21 days after.......
Keywords: Post-harvest loss; insect pests, mortality; plant extracts; larger grain borer
[1]. Fox T. Global food: waste not, want not. Inst Mech Eng London, Jan. Published online 2013:1-14.
[2]. Abass AB, Ndunguru G, Mamiro P, Alenkhe B, Mlingi N, Bekunda M. Post-harvest food losses in a maize-based farming system of semi-arid savannah area of Tanzania. J Stored Prod Res. 2014;57:49-57. doi:10.1016/j.jspr.2013.12.004
[3]. FAO. Global food losses and food waste. Published online 2011.
[4]. Atwal AS, Dhaliwal GS. Agricultural Pests of South Asia and Their Management. Kalyani Publishers; 2008.
[5]. Mihale MJ, Deng AL, Selemani HO, Mugisha-Kamatenesi M, Kidukuli AW, Ogendo JO. Use of indigenous knowledge in the management of field and storage pests around Lake Victoria basin in Tanzania. African J Environ Sci Technol. 2009;3(9):251-259. http://www.academicjournals.org/AJEST
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| Paper Type | : | Research Paper |
| Title | : | Comparative study on classical biochemical determination and supramolecular sensing of creatine in urine sample |
| Country | : | India |
| Authors | : | M.Amutha || M.Iswarys |
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: | 10.9790/264X-08041116 |
Abstract: Creatine is a breakdown product of creatine phosphate from muscle and protein metabolism in human. It is released at a constant rate by the body, and an approximately half of creatine originates from food. The results of the creatine tests can provide a very strong indication of how well the kidneys are functioning. The normal ranges for a creatine test are: 0.5 to 1.1. Milligrams (mg) per deciliter (DL) in women, 0.6 to 1.3 mg/DL in men and 0.5 to 1.0 mg/DL for children ages 3 to 18 years. If the level of creatine increased it could be the symptoms of Chronic or acute kidney disease, Congestive heart failure Diabetes Hyperthyroidism (overactive thyroid) Urinary tract obstruction, Muscular dystrophy and other muscle diseases. If your creatine test results are low, you may have: Severe liver disease......
[1]. Lafolie P, Beck O, Blennow G, Boreus L, Borg S, Elwin CE, et al. Importance of creatinine analyses of urine when screening for abused drugs. Clin Chem. 1991 Nov;37(11):1927-31. PubMed PMID: 1934467. Epub 1991/11/01.Eng
[2]. B D Toora 1, G Rajagopal Measurement of creatinine by Jaffe's reaction--determination of concentration of sodium hydroxide required for maximum color development in standard, urine and protein free filtrate of serum Indian J ExpBiol 2002 -40(3):352-4.
[3]. Syal K, Srinivasan A, Banerjee D. Streptomycin interference in Jaffe reaction—possible false positive creatinine estimation in excessive dose exposure. ClinBiochem. 2013;46(1–2):177–179
[4]. W. J. Birdsall &Bruce A. Weber Copper(I) and Copper(II) Complexes of Creatinine Journal of Coordination Chemistry2009 Volume 22, 1990 - Issue 3
[5]. Chartres, J.D.; Davies, M.S.; Lindoy, L.F.; Meehan, G.V.; Wei, G. Macrocyclic ligand design: The interaction of selected transition and post-transition metal ions with a 14-membered N2S2- donor macrocycle. Inorg. Chem. Commun. 2006, 9, 751-754.