Volume-18 ~ Issue-6 ~ June 2025

Abstract: Due to their stability and reversible redox activity, PEDOT-based copolymers are extensively investigated for electrochromic applications. For that reason, different modifications have been tried on the structure of PEDOT polymer in order to control both electrochemical and optical characteristics. Copolymerization of EDOT with carbazole monomer is one of the used modifications to alter and improve electrochromic properties. Despite these modifications, the electrochemical stability of the PEDOT-based copolymers is still a debate. To this end, a star-like shape of poly (EDOT-co-OctaCBz-POSS) copolymer was electrochemically synthesized by incorporating a carbazole-substituted polyhedral oligomeric silsesquioxane.......

Keywords: 3,4-ethylenedioxythiophene (EDOT), Carbazole, polyhedral oligomeric silsesquioxane (OctaCBz-POSS), PEDOT, Copolymer, electropolymerization.

[1] Y. Zhao Et Al., “Smart Windows Built With A Conductive Polymer With Net Zero Energy Consumption,” Cell Rep Phys Sci, Vol. 3, No. 10, 2022.
[2] S. Takamatsu, T. Takahata, M. Muraki, E. Iwase, K. Matsumoto, And I. Shimoyama, “Transparent Conductive-Polymer Strain Sensors For Touch Input Sheets Of Flexible Displays,” Journal Of Micromechanics And Microengineering, Vol. 20, No. 7, P. 075017, 2010.
[3] Z. Zhao, K. Xia, Y. Hou, Q. Zhang, Z. Ye, And J. Lu, “Designing Flexible, Smart And Self-Sustainable Supercapacitors For Portable/Wearable Electronics: From Conductive Polymers,” Chem Soc Rev, Vol. 50, No. 22, Pp. 12702–12743, 2021.
[4] R. J. Mortimer, D. R. Rosseinsky, And P. M. S. Monk, Electrochromic Materials And Devices. John Wiley & Sons, 2015.
[5] P. M. Beaujuge And J. R. Reynolds, “Color Control In Π-Conjugated Organic Polymers For Use In Electrochromic Devices,” Chem Rev, Vol. 110, No. 1, Pp. 268–320, 2010.

Abstract: Treatment of infectious diseases has become more challenging and has had a major influence on treatment rates due to the advent of new transmissible diseases and the rise in resistance of pathogens to available antibiotics. The use of nanoparticles as an antibiotic replacement has also gained attention due to the multidrug resistance of antibiotics to bacterial infections. This study investigated the synthesis and characterization of iron doped copper oxide nanoparticles (Fe-CuO Nps). Different characterization techniques which include X-ray diffraction (XRD), Scanning Electron Microscopy (SEM)/Energy Dispersive X-ray Spectroscopy.......

Keywords: Antimicrobial activity; Antioxidant activity; Fe-CuO Nps; Microbial infections

[1] A.O Adesina, O.R Adeoyo, O.. B., 2021. Antimicrobial Activity Of Iron Oxide Nanoparticles Stabilized By Alginate. J. Appl. Life Sci. Int. 24, 39–46. Https://Doi.Org/10.9734/JALSI/2021/V24i1130272
[2] Adesina, A.O., 2022. Antibacterial Activity Of Silver-Conjugated Magnetic Iron Oxide Nanoparticles. Sch. Int. J. Chem. Mater. Sci. 5, 23–28. Https://Doi.Org/10.36348/Sijcms.2022.V05i03.001
[3] Adesina, A.O. 2025a, 2025. Exploring The Antibacterial Activity Of Zinc Oxide Nanoparticles Against Some Selected Gram-Positive And Gram-Negative Bacteria 3214, 131–139.
[4] Æ, P.C.Æ.F.V.D.K., Hofmann, M.B.Æ.T., 2008. Nanoparticles : Structure , Properties , Preparation And Behaviour In Environmental Media. Ecotoxicology 17, 326–343. Https://Doi.Org/10.1007/S10646-008-0213-1
[5] Bhattacharjee, A.M.A., 2016. Cuo Nanostructures: Facile Synthesis And Applications For Enhanced Photodegradation Of Organic Compounds And Reduction Of P-Nitrophenol From Aqueous Phase. RSC Adv. 6, 41348–41363.
Https://Doi.Org/10.1039/C6RA03624D

ABSTRACT: A novel pyrazole derivative, 3-(1,3-bis(4-bromophenyl)-1H-pyrazol-4-yl)-2-(4-bromophenyl) acrylonitrile (BPPBPA), has been successfully synthesized and investigated as a highly selective and sensitive chemosensor for the detection of Cu (II) ions. Both absorption and emission spectroscopic studies clearly demonstrate the sensing capabilities of BPPBPA. Upon interaction with Cu (II) ions, the absorption spectrum exhibited a noticeable red-shift......

Keywords: BPPBPA Molecule; X-ray Photoelectron Spectroscopy (XPS); ESR; Vibrating Sample Magnetometry VSM; chemosensor; Cu (II) ion Detection.

[1]. S. Chauhan, D. Dahiya, V. Sharma, N. Khan, D. Chaurasia, A.K. Nadda, S. Varjani, A. Pandey, P. C. Bhargava, Advances From Conventional To Real Time Detection Of Heavy Metal(Loid)S For Water Monitoring: An Overview Of Biosensing Applications, Chemosphere, 2022, 307, 136124.
[2]. A. Mohapatra, S. Kumar, T. K. Acharya, C. Goswami, S. Bhaumik, Highly Stable Multi-Encapsulated Red-Emitting Cesium Lead Halide Nanocrystals For Efficient Copper Ion Detection And Imaging In Live Cells, J. Alloys & Compds, 2023, 947, 169453.
[3]. R. Singh, A. Umapathi, G. Patel, C. Patra, U. Malik, S. K. Bhargava, H. K. Daima, Nanozyme-Based Pollutant Sensing And Environmental Treatment: Trends, Challenges, And Perspectives, Sci. Total Environ., 2023, 854, 158771.
[4]. Elkhatat Am, Soliman M, Ismail R, Ahmed S, Abounahia N, Mubashir S, Fouladi S, Khraisheh M. Recent Trends Of Copper Detection In Water Samples. Bulletin Of The National Research Centre, 2021, 45(1), 218.
[5]. Alharthi Ss, Al-Saidi Hm. Spectrophotometric Determination Of Trace Concentrations Of Copper In Waters Using The Chromogenic Reagent 4-Amino-3-Mercapto-6-[2-(2-Thienyl) Vinyl]-1, 2, 4-Triazin-5 (4h)-One: Synthesis, Characterization, And Analytical Applications. Applied Sciences, 2020, 10(11), 3895

ABSTRACT: The universe is so vast that it’s hard to believe Earth is the only place with complex and intelligent life. While the idea of finding life on other planets is exciting, discovering elements and compounds on exoplanets1 (the planets that orbit stars outside our solar system) can be a tough task. But Humanity is resolutely addressing the barriers by developing and relying on "Astro-chemistry2.......

....

ABSTRACT: Parachor is a concept used in drug design to describe the physicochemical property of a compound, specifically its ability to balance between polar and non-polar interactions. It is a parameter that combines surface tension and molar volume to quantify how molecules interact with solvents, interfaces, and biological systems. Parachor is often applied to predict how molecules will behave in drug formulation. The paper deals with structure-activity relationships of phenols and its derivatives for the development of predictive models from several descriptors. To developing.......

Keywords Parachor, QSAR, Molecular descriptors, 3D MoRSE descriptors, FDI descriptors, RDF descriptors, Moreau autocorrelation descriptors, correlation coefficient, PRESS, SPRESS, PSE, LSE, PE

[1]. Parvez, A. ; Colin, A. F. ; Alan, M. ; Canadian Journal of Biochemistry 1975 ,53, 75-144
[2]. Viswanadhan, V. N. ; Ghose, A .K. ; Revankar, G. R. ; Exner, O. ; Nature 1, 1962, 890-891
[3]. Parvez, A.; Colin, A. F. ; Alan, M. ; Biochemical Pharmacology, 1975, 24, 1103-1109 [4]. Cynthia, D. S. ; Kapur, S. ; Verma, R. P. ; Melissa, R. ; J Med Chem , 2005 . 48 ,7234-7235
[5]. Dixit, S. ; Sikarwar, A. K. ; IOSR Journal of Applied Chemistry, 2022 ,15, 39-43.

ABSTRACT: Background: Pharmaceutical firms are confronting issues with pharmaceutical quality control. The classic OFAT approach required testing final products. It is time-consuming and expensive. Instead, the new AQbD strategy seeks to instill quality in the product throughout the manufacturing process, reducing the likelihood of product failure. A high-performance liquid chromatography (HPLC) method was devised to detect glucosamine sulphate impurities in bulk and solid dose formulations. There are many methods developed for the same but by using new DoE tools we can develop more robust method........

Keywords: Quality by design (QbD, Design of experiments (DoE), High performance liquid chromatography (HPLC), CPP (Critical process parameters).

[1]. Bhagwat Ashlesha, B., and K. M. Khedkar. "Impurity Profiling: A Review." Asian Journal of Pharmaceutical Research and Development 10.2 (2022): 135-143.
[2]. Jain, Anurag, and Sanjay Sharma. "Recent trends in impurity profiling of pharmaceutical products." MIT Int. J. Pharm. Sci 3 (2017): 1-6.
[3]. Landge, A. K., V. K. Deshmukh, and S. R. Chaudhari. "Impurities in pharmaceuticals-A review." Journal of Current Pharma Research 4.1 (2013): 1105.
[4]. ICH Guideline Q3A(R), Impurities in New Drug Products Revised Guidance on Federal Register. 65 (2000) 45085-90.
[5]. ICH Guideline Q6A Specifications, Test Procedures and Acceptance Criteria for New Drug Substances and New Drug Products. Chemical substances. 65(1999) 67488-92.