Series-1 (Jan. – Feb. 2021)Jan. – Feb. 2021 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Galangin inhibits angiogenesis and induces apoptosis of colon cancer in mice: Molecular estimation of CEA and VEGF |
| Country | : | Egypt |
| Authors | : | Tarek M. Okda || Mohamed A. Katry || Noha M. Ragab || Mohammad M. Abd-Alhaseeb |
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: | 10.9790/264X-0701010109  |
Abstract: Background and Aim: Colon cancer considers common and complicated cancer worldwide. Its treatment remains controversial and complex. 5-fluorouracil (5-FU) is the appropriate chemotherapy for colon cancer; however, it has serious side effects. Therefore, extensive research has been conducted on natural products to prevent cancer and used as adjuncts to chemotherapy to reduce 5-FU toxicity and side effects. Galangin is a natural product found in Alpinia officinarum. It acts as a prophylactic agent and used as an adjunct to chemotherapy in treating colon cancer. Methods: Sixty male albino mice were used in this study; six groups were designed (10 mice in each group): the control, carcinogen, prophylactic, galangin-treated, 5-FU-treated, and 5-FU- and galangin-treated groups. Reverse transcription-polymerase chain reaction was used to assess the expression of carcinoembryonic antigen (CEA), vascular..........
Key Word: CEA, angiogenesis, colon cancer, galangin, 5-FU
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[2]. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.
[3]. Rasool S, Kadla SA, Rasool V, Ganai BA. A comparative overview of general risk factors associated with the incidence of colorectal cancer. Tumor Biol. 2013;34(5):2469–76.
[4]. Roy A, Jauhari N, Bharadvaja N. 6 Medicinal Plants as. Anticancer Plants Nat Prod Biotechnol Implements Vol 2. 2018;2:109.
[5]. Gao Y, Xiao X, Zhang C, Yu W, Guo W, Zhang Z, et al. Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways. J Pineal Res. 2017;62(2):1–15.
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| Paper Type | : | Research Paper |
| Title | : | Production of Spirulina platensis in different media |
| Country | : | India |
| Authors | : | Naveen Kumar || Sumit Kumar |
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: | 10.9790/264X-0701011014 |
Abstract: Spirulina platensis was cultured in various medium as; Standard Zarrouk's Media (SZM), Modified Zarrouk's Media (MZM) and Tap Water Media (TWM). Dehydrated weight and pH was observed for 26 days on every day. In Standard Zarrouk's Media pH was noticed from 9.2 to 10.6, in MZM 9.0 to 10.4 and in TWM 7.40 to 7.45. Gradually increase in dry weight (dw) was observed with length of time of culture, 1.84 dw/L & 1.74 dw/L was attained in SZM and MZM correspondingly. S. platensis inoculated in TWM was live but growth was not increased, achieving higher dehydrated mass of 0.28 dw/L on 17-21 day of cultivation. Tap water prepared with various quantities of basic salts didn't exposed important change on S. platensis growth. Growth was influenced by mutually temperature and light in the experimentation and the effect of temperature was better to light in the experimental time..
Key Word: Spirulina platensis, cultured, SZM, MZM, TWM
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[3]. Cohen, Z., Vonshak, A. & Richmond, A., Fatty acid composition of Spirulina strains under various environmental conditions, Phytochemistry, 26 (1987), 2255-8.
[4]. Zahira, Y., Ali, E., Zainal, A., Mohamad, M. and Takrif, M. S., An overview: biomolecules from microalgae for animal feed and aquaculture, J Biol Res., 2014, 21(1): 6.
[5]. Gouveia, L., Batista, A.P., Sousa, I., Raymundo, A. and Bandarra, N.M. (2008). Microalgae in novel food products. In Papadopoulos, K.N. (Ed.), Food Chemistry Research Developments, Nova Science Publishers. Inc. pp. 1-37.
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| Paper Type | : | Research Paper |
| Title | : | Change of Organic Phase of Wood to Transparent Wood |
| Country | : | Egypt |
| Authors | : | Eman Tawfik Hussien || Fawzya Abdelkariim Soliman |
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: | 10.9790/264X-0701011518 |
Abstract:Background: Transparent wood (TW) structures are characterized as highly anisotropic or thick and isotropic but weak. Transparent wood laminates are investigated as load-bearing bio-composites with tunable mechanical and optical performances. Transparent wood has many applications such as solar cells, fabrics industry, Decorations and others. Materials and Methods: In this prospective study, pine wood was used as a template to be a transparent wood. The method used for lignin removal is very simple and cheap, using sodium hydroxide and sodium sulphite water bath at high temperature to get rid of lignin which harden the wood. Results: The transparent wood is characterized........
Key Word: Bio-composite; Cellulose; Lignin; Phase change; Pine wood; Transparent wood
[1]. Eichhorn SJ, Baillie CA, Zafeiropoulos N, Mwaikambo LY, Ansell MP, Dufresne A, Entwistle KM, Herrera-Franco PJ, Escamilla GC, Groom L, Hughes M, Hill C, Rials TG, Wild PM, Mater J. Review: Current international research into cellulosic fibres and composites. Journal of Materials Science. 2001; 36:2107–2131.
[2]. Zhu M, Li T, Davis CS, Yao Y, Dai J, Wang Y, AlQatari F, Gilman JW, Hu L. Transparent and haze wood composites for highly efficient broadband light management in solar cells. Nano Energy. 2016;26:332–339.
[3]. Donaldson L. Wood Sci. Technol. Cellulose microfibril aggregates and their size variation with cell wall type. Wood Science and Technology. 2007; 41(5):443–460.
[4]. Xu P, Donaldson LA, Gergely ZR, Staehelin LA. Dual-axis electron tomography: A new approach for investigating the spatial organization of wood cellulose microfibrils. Wood Science and Technology. 2007;41(2):101–116.
[5]. Gibson LJ, Soc JR. The hierarchical structure and mechanics of plant materials. Journal of Royal Society. 2012;9(76):2749–2766.
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| Paper Type | : | Research Paper |
| Title | : | Extraction of Acacia senegal MYB transcription factor mRNA by using homology searching approach: An important tree species of arid environment |
| Country | : | India |
| Authors | : | Kamlesh Pareek || Shiran K || J.C. Tewari || Anil Sharma || Praveen Kumar |
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: | 10.9790/264X-0701011924 |
Abstract: Acacia senegal one of the most dominant biomass producer of the sandy areas of the desert, belonging to (Fabaceae family and genus Acacia) commonly known as Kummat. These plants has well known to contain high levels and different types of secondary metabolites (gum Arabic), which are often responsible for their therapeutic and pharmacological activities. In-group of transcription factors of plants, MYB (myeloblastosis) gene family most diversified in various aspects. The study was to finding MYB genes sequences by using homological approaches. Applied standardized method for isolation and purification of genomic DNA from Acacia senegal leaves followed by an amplification of MYB genes. Primers has designed using online Genefisher2 and Primar3 software with high reproducibility at an optimal annealing temperature of 54°C. The isolated DNA has successfully amplified with all seven primers designed from homological MYB gene sequences of rice genome. Polymerase chain.......
Key Word: Acacia senegal, mRNA, myeloblastosis and transcription factors
[1]. Agarwal M, Hao Y, Kapoor A, Dong CH, Fujii H, Zheng X and Zhu JK. (2006). A R2R3 type MYB transcription factor is involved in the cold regulation of CBF genes and in acquired freezing tolerance. J BiolChem, 281:37636–37645.
[2]. Allan AC, Hellens RP and Laing WA. (2008). MYB transcription factors that colour our fruit. Cell, 13:99–102.
[3]. Barzegari, A., Vahed, SZ., Atashpaz, S., Khani, S. and Omidi, Y. (2010). Rapid and simple methodology for isolation of high quality genomic DNA from coniferous tissues (Taxusbaccata). Mol. Biol. Rep. 37, 833–837.
[4]. Cominelli E and Tonelli C. (2009). A new role for plant R2R3-MYB transcription factors in cell cycle regulation. Cell Res, 19:1231–1232.
[5]. Feller A, Machemer K, Braun EL and Grotewold E. (2011). Evolutionary and comparative analysis of MYB and bHLH plant transcription factors. Plant J, 66(1):94–116.
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| Paper Type | : | Research Paper |
| Title | : | Spermogramme du bouc du sahel au Niger |
| Country | : | Niger |
| Authors | : | MANI Mamman || MOUSSA GARBA Mahamadou || HAMADOU Issa || MARICHATOU Hamani || SAWADOGO Germain Jérôme |
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: | 10.9790/264X-0701012531 |
Abstract:Résumé Contexte: au Niger, le patrimoine génétique animal, comprend environ 36% de caprins dont 80% de race chèvre du Sahel. Cette dernière est omniprésente dans toutes les zones agro écologiques du pays et dans toutes les formes d'élevage rural qu'urbain, nomade que sédentaire. Dans l'optique de sa caractérisation zootechnique, il est apparu nécessaire d'établir les caractéristiques spermatiques des mâles, bases essentielles de la fonction de reproduction dont la maîtrise est capitale pour l'amélioration de la productivité et des productions animales......
[1]. Abébé G. Reproduction in Sheep and Goats; Chapter five. Sheep and Goat Production Handbook for Ethiopia. (En ligne) Accès internet: http://www.esgpip.org/handbook/Handbook (page consultée le 09/09/2013).
[2]. Leboeuf B, Manfredi E, Boue P, Piacère A, Brice G, Baril G, Broqua C, Humblot P, Terqui M. L'insémination artificielle et l'amélioration génétique chez la chèvre laitière en France. INRA Prod. Anim. 1998; 11, 171-181.
[3]. Baril G, Chemineau P, Cognie Y, Guérin Y, Leboeuf B. Orgeur P, et Vallet JC. Manuel de formation pour l'insémination artificielle chez les ovins et les caprins. Production et Santé Animale. FAO, Rome. 1993; 125p.
[4]. Chemineau P, Baril G, Leboeuf B, Maurel MC, Roy F, Pellicer-Rubio M, Malpaux B, Cognie Y. Implications des progrès récents en physiologie de la reproduction pour la conduite de la reproduction dans l'espèce caprine INRA Prod. Anim. 1999; 12, 135-146.
[5]. Kamal A, Gubartallah AA, Amel OB, and Babiker A. Comparative studies on reproductive performance of Nubian and Saanen Buks under climatic conditions of Khartoum. Journal of Animal and Veterinary Advances. 2005; 4 (11): 942-944.
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| Paper Type | : | Research Paper |
| Title | : | Investigation of Release Kinetics of Gallic Acid Loaded Microorganisms in Different Environments |
| Country | : | Turkey |
| Authors | : | Diclecan Bulut || Sibel Yiğitarslan |
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: | 10.9790/264X-0701013238 |
Abstract: Encapsulation is widely used in food, textile and pharmaceutical fields. The use of antioxidants, as a loading material of encapsulation of this study, contributes to the treatment of some diseases by neutralizing free radicals that occur as a result of oxidation. One of the compounds with the highest antioxidant effect among more than 4000 flavonoid types is gallic acid. It is found mostly in grapes, carob, sumac and green tea. It has been stated in several studies that this compound inhibits cancerous cells without damaging healthy ones. On the other hand, because of their supportive effects on health and reducing the risks of diseases, probiotics belonging to functional foods are preferred in recent years. In this study, antioxidant release mechanisms of gallic acid loaded probiotic-membraned......
Key Word: Lactobacillius acidophilus, Gallic acid, Release, Kinetic, Stomach, Bowel
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[4]. A. Faried, D. Kurnia, L.S. Faried, N. Usman, T. Miyazaki, H. Kato, H. Kuwano, Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines, International journal of oncology (2007) 30(3), 605-613.
[5]. M. Inoue, R. Suzuki, N. Sakaguchi, T. Takeda, Li Zong-Jun, Y. Ogihara, Y. Chen, Selective induction of cell death in cancer cells by gallic acid. Biological and Pharmaceutical Bulletin (1995) 18(11), 1526-1530..
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| Paper Type | : | Research Paper |
| Title | : | Determination of calcium and Vitamin D Levels and Relationships of Osteoporosis in Adults and Older age –Libya |
| Country | : | Libya |
| Authors | : | Aliya Idris Eghbili || Bubker A. Bader || Ibrahem Saad Ibrahem || Fawzi Farag Mohamed |
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: | 10.9790/264X-0701013945 |
Abstract: Vitamin D plays an important role in bone metabolism and maintaining bone health.
Recently, new evidence has revealed that vitamin D affects chronic diseases such as osteoporosis. Autoimmune diseases, cardiovascular diseases and certain cancers. The aim of this study was to evaluate the vitamin D status and the prevalence of vitamin D deficiency
Method: Three sample study included men and women and older. And 95 specimens with age range from 20 - 70 years. Serum 25(OH)D level was measured by ichromax II.Whili Blood samples from age and sex groups differential were obtained from various laboratories. Bone fracture samples. Collected Department of Fractures inside Central Teaching Hospital.Ajdabia-libya.....
Key Word: Vitamin D , osteoporosis ,fractures , ichromax II
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| Paper Type | : | Research Paper |
| Title | : | Characterization of a Hypothetical Protein from Bacillus cereus: an In Silico Approach |
| Country | : | Bangladesh |
| Authors | : | Md. Fazley Rabbi || Aradhan Sarkar |
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: | 10.9790/264X-0701014650 |
Abstract: Background: Bacillus cereus is a Gram positive, rod-shaped bacterium commonly found in soil and foods. The bacterial strain G1-1 contains many hypothetical proteins yet to be annotated. Annotation of these proteins might reveal new insights about this pathogenic organism; hence a hypothetical protein WP_000822694.1 was selected in this study for comprehensive characterization through in silico approach. Materials and Methods: Various bioinformatics resources were used in this study for characterization of the target protein. Physicochemical properties were estimated using ProtParam tool. CELLO and PSLpred server was used for subcellular localization prediction. Functional analysis was performed using NCBI-CDD and Pfam server. Secondary and tertiary structure ......
Key Word: Characterization, Hypothetical protein, Bacillus cereus, Functional analysis
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[5]. Frankard J, Li R, Taccone F, Struelens MJ, Jacobs F, Kentos A. Bacillus cereus pneumonia in a patient with acute lymphoblastic leukemia. Eur J Clin Microbiol Infect Dis. 2004;23(9):725-728.
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| Paper Type | : | Research Paper |
| Title | : | Application of Annona squamosa crude leaf extracts against Lasius niger, a black garden ant |
| Country | : | India |
| Authors | : | Dr. Sanjay Kumar Singh |
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: | 10.9790/264X-07015152 |
Abstract: Garden ants in black Lasius niger are a significant agricultural and urban pest that invade both indoor and outdoor living spaces and decimate crops. Workers are 3-5 mm length and lustrous dark black. It has been observed that workers' sizes increase over successive generations as the colony ages. Lasius niger workers were sprayed with aqueous extracts of fresh Annona squamosa leaves at concentrations of 100%, 75%, 50%, 25%, 10%, 5%, 1%, and 0.1%. the dilution determined using the weight per volume formula with RO Water as the solvent. The definition of mMortality is dead / number of subjects x 100%. Both a positive control group that was exposed to the insecticide Chlorpyriphos 2% and a negative control group that was exposed to RO Water were employed as controls in our study. The Annona squamosa leaves extract successfully killed Lasius niger at concentrations of Extract leaves 25%, 50%, 75%, and 100% (w/v), but was less effective when compared to the positive control insecticide Chlorpyriphos 0.2%, and ineffective at concentrations of Extract leaves 0.1%, 5%, and 10%. While the extract's LD50 was extremely high (61.30%).
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