Abstract: The effect of African walnut (Plukenetiaconophora) on the serum acid phosphatase and prostate specific antigen levels in male albino rats were investigated. Eighteen wistar albino rats were used for the experiment. The rats test group was fed with a diet prepared with 1% African walnut and 99% of the rat chow. The control group received only the standard feed (rat chow). The baseline group was sacrificed at the onset of the study to ascertain initial conditions. The study lasted for thirty one days after which the serum acid phosphatase and prostate specific antigen levels were estimated using spectophotometric method. The acid phosphatase kit (Bio systems) and PSA ELISA kit (BioCheck) were used for the assay. The result showed that there was no statistically significant difference (P>0.05) in prostate specific antigen level of the test group (3.72±1.243) compared to the baseline (4.08±2.158) and control (5.13±2.416). The total acid phosphatase (19.60±8.148) and prostatic acid phosphatase (15.36±4.836) levels of the test group showed no statistically significant (P>0.05) difference compared to the levels in baseline....
Keywords: Plukenetiaconophora, Prostate cancer, Phytochemicals, Acid phosphatase,Prostate Specific Antigen Histological
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