Abstract: Natural products are still major potential sources of innovative therapeutic agents for various conditions, including infectious diseases as they represent an unmet source of chemical diversity. This study was conducted to determine the anti-trypanosomal properties of Artemisia herba-alba and Rosmarinus officinalis in vivo settings. We have reviewed previous studies in the literature, which support the therapeutic activity of these plants and the data suggest that A. herba-alba as well as R. officinalis have anti-trypanosomal activites, and reinforce the use of this plant as an alternative remedy for microbial infection in traditional medicine.
Keywords: Artemsia herba-alba, Rosmarinus officinalis, anti-trypanosomal properties
[1] Akrout, A., Mighri, H., Krid, M., Thabet, F., Turki, H., El-Jani, H., &Neffati, M. (2012). Chemical composition and antioxidant activity of aqueous extracts of some wild medicinal plants in Southern Tunisia. International Journal of Life Science and Medical Science, 2(1), 1-4.
[2] Al-Shamaony, L., Al-Khazraji, S. M., &Twaij, H. A. (1994). Hypoglycaemic effect of Artemisia herbaalba. II. Effect of a valuable extract on some blood parameters in diabetic animals. Journal of Ethnopharmacology, 43(3), 167-171.
[3] Altinier G, Sosa S, Aquino RP, Mencherini T, Loggia RD, Tubaro A (2007). Characterization topical anti-inflammatory compounds in Rosmarinus officinalis L. J. Agri. F. Chem., 55: 1718-23.
[4] Awad, F. M. A., Mohamed, M. A., Osman, A. Y., Abu-Hassan, Z. A., & Ibrahim, N. (2014). In vivo assessment of anti-trypanasomal effect of rosemary (Rosmarinus officinalis) in rabbits. IOSR J Agric Vet Sci, 7, 45-54.
[5] Awad, F. M., Hasan, Z. A. B. A., & Osman, A. Y. (2013). Antitrypanosomal effects of crude ethanolic extract of Artemisia herbaalbafollwing experimental infection of rabbits.