Abstract: A simple, rapid and precise method is developed and validated for the estimation of Secnidazole in solid dosage form by RP-HPLC. The proposed method produced results in accordance with the ICH guidelines. The assay value for Secnidazole is found to be 100.26%. The linearity of Secnidazole was found to be linear with a correlation coefficient of 0.999. The method developed and validated is precise with an RSD value of 0.17. Hence the proposed method is useful in routine analysis and the method is capable of producing good sensitivity.
Keywords: Secnidazole, linearity, correlation coefficient, assay and ICH.
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