Abstract: Bisphenol A (BPA) is a synthetic chemical extensively used in plastics, resins and food packaging, and is recognized globally as a potent endocrine-disrupting compound. Its continuous discharge into aquatic ecosystems has raised significant ecological and human health concerns. Labeo rohita (rohu), one of the most important freshwater fish in Tamil Nadu’s aquaculture, serves as an ideal model organism to assess toxicological stress due to its commercial value.....
Keyword: Bisphenol A, Labeo rohita, endocrine disruption, haematology, oxidative stress, histopathology
[1].
N. Denslow, M. Sepúlveda, Ecotoxicological effects of endocrine disrupting compounds on fish reproduction. J.P. Babin, J. Cerda, E. Lubzens (Eds.), The Fish Oocyte from Basic Studies to Biotechnological Applications, E-Publishing Inc., Netherlands (2007), pp. 254-322.
[2].
L.N. Vandenberg, M.V. Maffini, C. Sonnenschein, B.S. Rubin, A.M. Soto. Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption. Endocr. Rev., 30 (2009), pp. 75-95. [3]. A.L. Filby, C.R. Tyler. Molecular Characterization of Estrogen Receptors 1, 2a, and 2b and Their Tissue and Ontogenic Expression Profiles in Fathead Minnow (Pimephales promelas). Biology of Reproduction, Volume 73, Issue 4, 1 October 2005, Pages 648–662.
[4]. Kourouma, A., Quan, C., Duan, P., Qi, S., Yu, T., Wang, Y., Yang, K., 2015. Bisphenol A induces apoptosis in liver cells through induction of ROS. Adv. Toxicol. 2015, 1–10.
[5]. Crain, D.A., Eriksen, M., Iguchi, T., Jobling, S., Laufer, H., LeBlanc, G.A., Guillette, L.J., 2007. An ecological assessment of bisphenol-A: evidence from comparative biology.Reprod. Toxicol. 24, 225–239