iosr-JDMS   Volume-24 ~ Issue-2 ~ February 2025

Abstract: Purpose: To investigate the influence of digital device use (computers, laptops, tablets, smartphones) on dry eye disease (DED) in a pediatric population. Settings and Design: This was a cross‑sectional study. School children studying in grades 5–9 at two private schools. Methods: In this study, 462 children underwent ocular examination including tear film breakup time (TBUT) and Schirmer’s test. Questionnaires were administered for collecting information on the type and duration of digital device usage separately for academic and leisure activities and the Ocular Surface Disease Index (OSDI) score.
Results: The mean age......

[1] Kim TH, Moon NJ. Clinical Correlations Of Dry........

Abstract: Adverse drug reaction can be predictable or unpredictable. The effectiveness of ATT such as Rifampicin , Isoniazid , Pyarazinamide , Ethambutol are complicated by the severity of adverse reaction. Lichenoid drug reaction incidence among patients taking first line Antitubercular drugs is roughly 10%1. Clinically these lesions resemble lichen planus with subtle differences.......

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Abstract: Orofacial clefting is one of the most common craniofacial defects affecting neonates. It must be addressed immediately as it can lead to a wide array of oral health issues, causing difficulty in speech, facial development, feeding, dental health, and psychological challenges. This clinical report describes a neonate with a cleft palate in whom a feeding plate was delivered using vacuum forming

Keywords: Cleft Palate, Infant, Feeding Plate Obturator

[1] Bansal R, Pathak AK, Bhatia B, Gupta S, Gautam KK. Rehabilitation Of A One-Day Old Neonate With Cleft Lip And Palate Using Palatal Obturator: A Case Report. Int J Clin Pediatr Dent 2012;5(2):145-147.
[2] Ravichandra KS, Vijayaprasad KE, Vasa AAK, Suzan S. A New Technique Of Impression Making For An Obturator In Cleft Lip And Palate Patient. J Indian Soc Pedod Prev Dent, 2010; 8(4); 311-14.
[3] Malik P, Agarwal A, Ahuja R. Feeding Appliance For An Infant With Cleft Lip And Palate: Pak Oral Dental J 2012;32(2):264-66.
[4] Gupta R, Singhal P, Mahajan K, Singhal A. Fabricating Feeding Plate In CLP Infants With Two Different Material: A Series Of Case Report. J Indian Soc Pedod Prev Dent 2012;30:352-5.
[5] Sikligar S, Shah S, Mulchandani V, Rachappa MM, Dave B. A Ray Of Hope In Cleft Lip And Palate Patients: Case Reports: European Journal Of Dental Therapy And Research 2014:3 (2):217-220.

Abstract: Introduction With the increasing rate of caesarean section worldwide, there is a concerning rise of second stage cesarean section. Interventions in the second stage in a fully dilated cervix and deeply impacted head poses quite a risk to both mother and fetus . The objective of the present study was to observe and analyse the various fetomaternal complications in subjects who underwent caesarean section in second stage.
Meterials And Methods.....

[1] Loudon JAZ, Groom KM, Hinkson L ,Harrington D ,Paterson-Brown S. Changing Trends In Operative Delivery Performed At Full Dilution Over A 10 Year Period. J Obstet Gynaec 2010;30:370-5
[2] Vousden N Cargill Z, Briley A Tydeman G, Shennan AH .Cesarian Section At Full Dilation : Incidence,Impact And Current Management. The Obstetrician Gynaecologist 2014 Jul 1:16( 3 ) 199-205
[3] Unterscheider J, Mcmenamin M, Cullinane F,Rising Rates Of Caesarean Deliveries At Full Cervical Dilation : A Concerning Trend, European J Obstet Gynecol 2010 Apr 1;157 (2) :141-4.
[4] Azza Jaafar B, Rihab Jaafar, Yassir Ahmed Mohammed E , Awad Ali MA, Siddig Omer MH. Maternal And Perinatal Outcome Among Women Underwent 2nd Stage Vs First Stage Caesarean Delivery At Ibrahim Malik Hospital In Sudan. WJ Gynecol Womens Health. 1(3):2018.

Abstract: Introduction: Proximal gastric cancer, especially at the esophagogastric junction, presents a significant therapeutic challenge due to its high morbidity, mortality, and generally poor prognosis. This study aimed to assess the aetiological and pathological determinants of postoperative complications in proximal gastric cancer surgery. Methods: This prospective observational study was conducted at the National Institute of Cancer Research and Hospital Department of Surgical Oncology. Patient selection followed predefined inclusion and exclusion criteria, leading to a study cohort of 50 eligible individuals. Data collection utilized a structured case record form, and the postoperative outcome was evaluated by examining complications and measuring hemoglobin and serum albumin levels........

Key Word: Proximal Gastric Cancer, Etio-pathological determinants, Hemoglobin, Serum albumin

[1] Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Et Al. Global Cancer Statistics 2020: GLOBOCAN Estimates Of Incidence And Mortality Worldwide For 36 Cancers In 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249.
[2] Thrift AP, Wenker TN, El-Serag HB. Global Burden Of Gastric Cancer: Epidemiological Trends, Risk Factors, Screening And Prevention. Nat Rev Clin Oncol. 2023 May;20(5):338-349. Doi: 10.1038/S41571-023-00747-0. Epub 2023 Mar 23. PMID: 36959359.
[3] Ahn HS, Lee HJ, Yoo MW, Jeong SH, Park DJ, Kim HH, Kim WH, Lee KU, Yang HK. Changes In Clinicopathological Features And Survival After Gastrectomy For Gastric Cancer Over 20 Years. Br J Surg. 2011 Feb;98(2):255-260.
[4] Vanlalhlua C, Lalramlawmi R. Role Of Esophagogastroduodenoscopy For Detection Of Upper GI Malignancy – Our Experience. Ann Int Med Den Res. 2020;6(2):SG05-SG08

Abstract: Background: High-risk papillary thyroid carcinoma (PTC) poses significant challenges due to its aggressive nature, requiring comprehensive surgical strategies such as central compartment clearance (CCC) to enhance patient outcomes. This study aimed to evaluate the surgical and long-term outcomes associated with CCC in a cohort from the Combined Military Hospital, Dhaka. Methods: This retrospective analysis included 100 patients diagnosed with high-risk PTC who underwent CCC from 2015 to 2022. Patient demographics, clinical presentations, operative details, postoperative complications, and long-term outcomes......

Keywords: Papillary Thyroid Carcinoma, Central Compartment Clearance, High-Risk PTC, Surgical Outcomes, Recurrence, Survival Analysis, Postoperative Complications

[1] Rego-Iraeta A, Pérez-Méndez LF, Mantinan B, Garcia-Mayor RV. Time Trends For Thyroid Cancer In Northwestern Spain: True Rise In The Incidence Of Micro And Larger Forms Of Papillary Thyroid Carcinoma. Thyroid. 2009 Apr;19(4):333–40.
[2] Ito Y, Fukushima M, Kihara M, Takamura Y, Kobayashi K, Miya A, Et Al. Investigation Of The Prognosis Of Patients With Papillary Thyroid Carcinoma By Tumor Size. Endocr J. 2012;59(6):457–64.
[3] Leboulleux S, Rubino C, Baudin E, Caillou B, Hartl DM, Bidart JM, Et Al. Prognostic Factors For Persistent Or Recurrent Disease Of Papillary Thyroid Carcinoma With Neck Lymph Node Metastases And/Or Tumor Extension Beyond The Thyroid Capsule At Initial Diagnosis. J Clin Endocrinol Metab. 2005 Oct;90(10):5723–9.
[4] Ito Y, Miyauchi A, Yamamoto M, Masuoka H, Higashiyama T, Kihara M, Et Al. Subset Analysis Of The Japanese Risk Classification Guidelines For Papillary Thyroid Carcinoma. Endocr J. 2020 Mar 28;67(3):275–82.
[5] Rahman MM, Siddiquee BH, Rahman HMM, Rahaman MH, Rahaman ML, Talukdar S. Central Compartment Involvement In T3 & T4 Papillary Thyroid Carcinoma. Bangladesh Journal Of Otorhinolaryngology [Internet]. 2022 [Cited 2024 Nov 5];28(2):149–56. Available From: Https://Www.Banglajol.Info/Index.Php/BJO/Article/View/64298.

Abstract: This study evaluated the adverse effects of drugs commonly used in the treatment of rheumatoid arthritis among patients in West Bengal, India. It focused on medications such as methotrexate, hydroxychloroquine, leflunomide, and biologic agents, assessing their impact on patient health over a period of one year. The research findings highlighted that gastrointestinal disturbances, hepatotoxicity, and immunosuppressive-related infections were among the most frequently reported side effects......

Keywords: Rheumatoid arthritis, adverse effects, methotrexate, hydroxychloroquine, leflunomide, biologic agents, West Bengal, hepatotoxicity, immunosuppressive infections, drug safety

[1] Basu, D., Chatterjee, D., & Roy, S. (2022). Assessment Of Adverse Drug Reactions In Patients With Rheumatoid Arthritis: A Study From West Bengal. Indian Journal Of Pharmacology, 54(2), 165-171.
[2] Bongartz, T., Sutton, A. J., Sweeting, M. J., Buchan, I., Matteson, E. L., & Montori, V. (2006). Anti-TNF Antibody Therapy In Rheumatoid Arthritis And The Risk Of Serious Infections And Malignancies: Systematic Review And Meta-Analysis Of Rare Harmful Effects In Randomized Controlled Trials. JAMA, 295(19), 2275-2285.
[3] Chatterjee, A., Ghosh, S., & Dasgupta, D. (2021). Drug Safety In Rheumatoid Arthritis: A Retrospective Study. Journal Of Clinical Rheumatology, 27(4), 202-208.
[4] Dutta, S., Kar, S., Saha, A., & Sengupta, S. (2020). Adverse Effects Of Sulfasalazine In Rheumatoid Arthritis Treatment: A Clinical Observation Study. Indian Journal Of Rheumatology, 16(3), 210-218.
[5] Lepre, L., Caporali, R., & Carrara, G. (2014). Retinal Toxicity And Nephrotoxicity Of Hydroxychloroquine: Review Of The Literature And Implications For Rheumatology Practice. Clinical Ophthalmology, 8, 1671-1680.

Abstract: Adipose derived mesenchymal stem cells undergo multipotential differentiation to biotransform into variety of tissues such as adipocytes, smooth muscle cells, osteocytes, chondrocytes, glia, neurons, myeloid and erythroid hematopoietic cells for their wider dermatological use in treatment of autoimmune disease, wound healing and skin neoplasms. Clinical trials indicate their limited use due to several challenges and complications. A lot of skin tissue engineering issues on mechanisms, molecular pathways still need investigations to develop full-proof safe adipose cell derived skin......

Keywords: Dermatology clinical trials, Adipose derived stem cells, Skin diseases, Adipose derived Stem Cell transplantation

[1] Herzog EL, Chai L, Krause DS. Plasticity Of Marrow-Derived Stem Celle. Blood 2003; 102: 3483-93.
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Prodinger CM, Reichelt J, Bauer JW, Laimer M, Current And Future Perspectives Of Stem Cell Therapy In Dermatology. Ann Dermatol 2027; 29: 667-87.
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[5] Choi HR, Byun SY, Kwon SH, Park KC. Niche Interactions In Epidermal Stem Cells. World J Stem Cells 2015; 7: 495-501..

Abstract: Gartner’s duct cyst is an unusual vaginal cyst that develops from the Gartner’s duct, the residual embryonic structure of the caudal end of the mesonephric duct in females. Often discovered incidentally during routine pelvic exams on the anterior or lateral vaginal wall, these cysts typically exhibit no symptoms. Although the occurrence of Gartner’s duct cysts during pregnancy or at birth is exceedingly rare and has been scarcely documented in the literature, we encountered a pregnant patient who was referred to our hospital due to a protruding vaginal mass causing obstruction in the birth canal. Diagnosis was established through typical clinical examination and radiological findings, and after draining the Gartner’s duct cyst, a normal vaginal delivery was successfully performed.....

[1] Hoogendam Jp, Smink M. Gartner‘S Duct Cyst. N Engl J Med. 2017 Apr 6;376(14):E27, Doi: 10.1056/ Nejmicm1609983; Pmid: 28379795
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[3] Theodoridis Td, Pappas Pd, Grimbizis Gf. Surgical Management Of Congenital Uterine Anomalies (In- Cluding Indications And Surgical Techniques). Best Pract Res Clin Obstet Gynaecol. 2019 Aug;59:66- 76, Doi: 10.1016/J.Bpobgyn.2019.02.006; Pmid: 30910446
[4] Gadbois Wf, Duckett Jw Jr. Gartner‘S Duct Cyst And Ipsilateral Renal Agenesis. Urology. 1974 Dec;4(6):720-1, Doi: 10.1016/0090-4295(74)90255- 6; Pmid: 4454113
[5] Cope Ag, Laughlin-Tommaso Sk, Famuyide Ao, Gebhart Jb, Hopkins Mr, Breitkopf Dm. Clini- Cal Manifestations And Outcomes In Surgically Managed Gartner Duct Cysts. J Minim Inva- Sive Gynecol. 2017 Mar-Apr;24(3):473-477, Doi: 10.1016/J.Jmig.2017.01.003; Pmid: 28089812.

Abstract: Background: Kennedy Class-IV edentulous patients require prosthetic rehabilitation that balances aesthetic satisfaction and functional efficiency. Acrylic partial dentures (APDs) have long been a standard treatment due to their affordability and structural stability, whereas flexible partial dentures (FPDs) have gained popularity due to their improved comfort and adaptability. However, comparative data on sore area formation and long-term aesthetic acceptance between these two materials remain limited. This study aims to evaluate aesthetic preference and mucosal.....

Keywords: Flexible Partial Dentures, Acrylic Partial Dentures, Kennedy Class-IV, Aesthetic Satisfaction, Sore Area Formation, Prosthodontics, Mucosal Adaptation

[1] Akinyamoju CA, Dosumu OO, Taiwo JO, Ogunrinde TJ, Akinyamoju AO. Oral Health-Related Quality Of Life: Acrylic Versus Flexible Partial Dentures. Ghana Med J [Internet]. 2019 Jun [Cited 2025 Feb 6];53(2):163–9. Available From:
Https://Www.Ncbi.Nlm.Nih.Gov/Pmc/Articles/PMC6697771/
[2] Shetty PK, Shetty BY, Hegde M, Prabhu BM. Rehabilitation Of Long-Span Kennedy Class IV Partially Edentulous Patient With A Custom Attachment-Retained Prosthesis. J Indian Prosthodont Soc. 2016;16(1):83–6.
[3] Akinyamoju CA, Ogunrinde TJ, Taiwo JO, Dosumu OO. Comparison Of Patient Satisfaction With Acrylic And Flexible Partial Dentures. Niger Postgrad Med J. 2017;24(3):143–9.
[4] Binaljadm TM. Flexible Denture: A Literature Review. Cureus [Internet]. 2024 Mar 3 [Cited 2025 Feb 6];16(3). Available From:
Https://Www.Cureus.Com/Articles/231939-Flexible-Denture-A-Literature-Review
[5] Kovacevska G, Mijoska A. FLEXIBLE POLYMER DENTURES - CONTEMPORARY SOLUTIONS FOR SUPERIOR ESTHETIC AND COMFORТ. Knowledge - International Journal

Abstract: The retention and stability of complete dentures are significantly influenced by the adaptation of the denture base to the supporting tissues of the edentulous ridge, particularly in the post-palatal seal area. This study explores the influence of palatal vault depths on denture base adaptation in the post-palatal seal region, comparing conventional processing techniques with those incorporating palatal anchoring. The retention of a complete denture is determined by the intimate fit between the denture base and the mucosal surface, with factors such as surface tension, adhesion.....

Keywords: Distortion, Polymerization shrinkage, Polymethyl methacrylate, Heat-polymerized

[1] Laughlin GA, Eick JD, Glaros AG, Young L, Moore DJ. A Comparison Of Palatal Adaptation In Acrylic Resin Denture Bases Using Conventional And Anchored Polymerization Techniques. Journal Of Prosthodontics. 2001 Dec;10(4):204-11.
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Abstract: Glucocorticoid therapies are extensively used in a wide range of medical conditions including respiratory, allergic, inflammatory and autoimmune diseases. Inappropriate use of therapeutic doses of glucocorticoids can lead to many adverse effects including hypothalamic pituitary axis suppression and Cushing's syndrome. Cushing's syndrome is a rare entity in children. Adrenal tumour is the common cause of this syndrome in young children, whereas, iatrogenic causes are more common among older children. In this report, we present a nine-year-old boy of exogenous Cushing syndrome due to prolonged use of oral prednisolone for JIA who also developed posterior subcapsular cataract.

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