Series-1 (Nov. – Dec. 2020)Nov. – Dec. 2020 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Osteoporosis And Cardiovascular Disease Are Linked To Sharp Reduction In Mitochondrial Synthase, Phospholipase , Cox2 Enzymes, And TXA2 Alpha Subunits Productions, And Linked To The Feedback Of VEGF-A Alpha Subunits From TXA2 Productions |
| Country | : | Egypt |
| Authors | : | Ashraf Marzouk El Tantawil |
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: | 10.9790/264X-0606010106  |
Abstract: osteoporosis and cardiovascular disease are linked to sharp reduction in mitochondrial synthase, phospholipase , Cox2 enzymes, and TXA2 alpha subunits productions. Then mitochondrial enzymes : TXA2 synthase, cox2, and phospholipase enzymes are so necessary for acting on inflammations molecules which found in interstitium fluid and in blood for TXA2 subunits productions, and then for feedback for VEGF-A subunits synthesis, where the last VEGF-A subunits are so necessary for PPARs genes re activations, and for re-stimulation the endothelin-1 synthesis and re stimulations the G_actin filaments for recompleting the anti-inflammation cycles and processes.
[1]. Bostrom K, Watson KE, Horn S, Wortham C, Herman IM, Demer LL. Bone morphogenetic protein expression in human atherosclerotic lesions. J Clin Invest. 1993;91:1800–1809. [PMC free article] [PubMed] [Google Scholar] [Ref list].
[2]. Shanahan CM, Cary NR, Metcalfe JC, Weissberg PL. High expression of genes for calcification-regulating proteins in human atherosclerotic plaques. J Clin Invest. 1994;93:2393–2402. [PMC free article] [PubMed] [Google Scholar] [Ref list].
[3]. Dhore CR, Cleutjens JP, Lutgens E, Cleutjens KB, Geusens PP, Kitslaar PJ, Tordoir JH, Spronk HM, Vermeer C, Daemen MJ. Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Arterioscler Thromb Vasc Biol. 2001;21:1998–2003. [PubMed] [Google Scholar] [Ref list].
[4]. The link between osteoporosis and cardiovascular disease. Clin Cases Miner Bone Metab. 2008 Jan-Apr; 5(1): 19–34.
PMCID: PMC2781192 PMID: 22460842 Ghada N. Farhata and Jane A. Cauleyb. Clinical Cases in Mineral and Bone Metabolism CIC Edizioni Internazionale.
[5]. Watson KE, Bostrom K, Ravindranath R, Lam T, Norton B, Demer LL. TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify. J Clin Invest. 1994;93:2106–2113. [PMC free article] [PubMed] [Google Scholar] [Ref list]..
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| Paper Type | : | Research Paper |
| Title | : | Environmentally benign synthesis and Biological evaluation of Ni(II) complexes with bi-anionic tetradentate (NOO'N) ligand |
| Country | : | India |
| Authors | : | Pragya Singh || U.S.Yadav || K.P.Srivastava |
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: | 10.9790/264X-0606010712 |
Abstract: A facile, efficient, environmentally benign and economical method under microwave irradiation in green medium has been used for the synthesis of a series of octahedral complex es of Ni(II) with NOO'N donor ligand, o-phenylene-bis(o-hydroxy acetophenone) diamine as primary bi-anionic tetradentate ligand and quinoline, pyridine etc. different monodentate secondary ligands. All the eco-friendly synthesized complexes were characterized by elemental analysis, conductivity and magnetic moment measurements and spectroscopic analyses. The obtained results were compared with conventional methods. The anti-microbial activity of the investigated ligand and its Ni(II) complexes clearly indicates that the complexes are found to be more active than the free ligand towards the tested microbes.
Key Words: Nickel(II) complexes, microwave irradiation, octahedral geometry, anti-microbial activity
[1]. Chohan, Z. H.; Arif, M.; Akhtar, M. A.; Supuran, C.T.; Bioinorganic Chemistry and Applications, 2006, 1-11.
[2]. Anastas, P.; Heine, L. G.; Williamson, T. C.; Green Chemical Synthesis & Process, 2000, Oxford University, Press, N Y.
[3]. Sheldon, R. A.; "Matrices of Green Chemistry and Sustainability: Past, Present and Future", ACS Sustainable Chem. Eng., 2018, 6, 32-48.
[4]. Leadbeater, N.E.; Microwave Heating as a tool for Sustainable Chemistry, 2010, CRC Press, Boca Raton, Florida, USA.
[5]. Polshettiwar, V.; Aqueous Microwave Assisted Chemistry: Synthesis and Catalysis, 2010, RSC, Cambridge, UK.
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| Paper Type | : | Research Paper |
| Title | : | Encapsulation of Probiotics and its Optimization |
| Country | : | India |
| Authors | : | Vijay Kumar || Prof.D.Jaya Prakash |
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: | 10.9790/264X-0606011318 |
Abstract: This study reports the morphology and survivability of the probiotics Bacillus subtilis, Pediococcusacidilactici, Saccharomyces boulardii encapsulated in different alginate concentrations (1%, 2%, 2.5%, 3%, 3.5%, 4%) The release of encapsulated cells when exposed to various pH levels (2, 4, 7, 9, 11) and salt solutions of Sodium Chloride (NaCl) (10ppt, 15ppt, 20ppt, 25ppt, 30ppt) was also assessed. The survivability increased proportionately with increased alginate concentrations. The survival of the encapsulated probiotics was slightly better at moderate pH and low salt concentrations.
Key Words: probiotics, Sodium Chloride, survivability, encapsulated probiotics, concentration
[1]. Probiotics, prebiotics, and microencapsulation: A review.
Sarao LK, Arora M. Crit Rev Food Sci Nutr. 2017 Jan 22;57(2):344-371. doi: 10.1080/10408398.2014.887055. PMID: 25848935 Review.
[2]. Co-microencapsulation of Lactobacillus plantarum and DHA fatty acid in alginate-pectin-gelatin biocomposites.
Vaziri AS, Alemzadeh I, Vossoughi M, Khorasani AC. CarbohydrPolym. 2018 Nov 1;199:266-275. doi: 10.1016/j.carbpol.2018.07.002 Epub 2018 Jul 10. PMID: 30143129
[3]. Growth and survival of microencapsulatedprobiotics prepared by emulsion and internal gelation.
Qi W, Liang X, Yun T, Guo W. J Food Sci Technol. 2019 Mar;56(3):1398-1404. doi: 10.1007/s13197-019-03616-w. Epub 2019 Feb 21.PMID: 30956319 Free PMC article.
[4]. Microencapsulation of probiotics by efficient vibration technology. Olivares A, Silva P, Altamirano C. J Microencapsul. 2017 Nov;34(7):667-674. doi: 10.1080/02652048.2017.1390005. Epub 2017 Oct 23 PMID: 28985684
[5]. Microencapsulation in food science and biotechnology. Nazzaro F, Orlando P, Fratianni F, Coppola R. CurrOpinBiotechnol. 2012 Apr;23(2):182-6. doi: 10.1016/j.copbio.2011.10.001. Ep 2011 Oct 22. PMID: 22024623 Review.