iosr-JDMS   Volume-25 ~ Issue-10 ~ Oct. 2026

Abstract: About 9% of gingival growths are peripheral ossifying fibromas (POFs), which are reactive soft-tissue lesions that typically develop on the interdental papilla. They are thought to be caused by gingival connective tissue, the periosteum, or the periodontal membrane. In clinical terms, POF manifests as a distinct, sessile or pedunculated gingival mass, usually less than 1.5 cm1, and may be a maturation of pyogenic granuloma or peripheral giant cell granuloma2.

Keywords: Peripheral Ossifying Fibroma, Gingival Mass, Fibro-Osseous Lesion, Maxillary Expansion STATEMENTS AND DECLARATIONS-I declare that I have no financial or non-financial competing interests related to this work. I also confirm that I have not received any funding for the preparation of this manuscript

[1]. Poon CK, Kwan PC, Chao SY. Giant peripheral ossifying fibroma of the maxilla. Journal of Oral and Maxillofacial Surgery. 1995 Jun;53(6):695–8.
[2]. Bhaskar SN, Jacoway JR. Peripheral fibroma and peripheral fibroma with calcification: report of 376 cases. J Am Dent Assoc. 1966 Dec;73(6):1312–20.
[3]. Kenney JN, Kaugars GE, Abbey LM. Comparison between the peripheral ossifying fibroma and peripheral odontogenic fibroma. Journal of Oral and Maxillofacial Surgery. 1989 Apr;47(4):378–82.
[4]. Sujatha G, Gopalakrishnan S, Jayanandan M, Selvakumar J, Ramasamy M. Peripheral ossifying fibroma – report of a case. 2018 Sep 14;
[5]. Growth potential of peripheral ossifying fibroma - PubMed [Internet]. [cited 2024 Jan 17]. Available from: https://pubmed.ncbi.nlm.nih.gov/3479457/

Abstract: Introduction. Les tumeurs carcinoïdes pulmonaires sont des néoplasies neuroendocrines rares, généralement de croissance lente, mais susceptibles d’entraîner des manifestations respiratoires sévères lorsqu’elles siègent au niveau des grosses voies aériennes. Observation. Nous rapportons le cas d’une patiente de 30 ans, sans antécédent pathologique notable, admise pour toux sèche et dyspnée évoluant depuis trois mois. La TDM thoracique a montré un trouble ventilatoire du lobe inférieur droit associé à une obstruction de la bronche souche droite. L’évolution a été marquée par une détresse respiratoire aiguë avec hémoptysie.......

Key word: carcinoïde pulmonaire ; tumeur neuroendocrine ; bronche souche ; atélectasie ; bronchoscopie ; obstruction bronchique.

[1]. Baudin E, Durand A, Buikhuisen W, et al. European Society of Neuroendocrine Tumors (ENETS) 2025 guidance paper for lung and thymic carcinoids. J Neuroendocrinol. 2026;38(4):e70174. doi:10.1111/jne.70174.
[2]. Baudin E, Caplin M, Garcia-Carbonero R, et al. Lung and thymic carcinoids: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2021;32(4):439-451. doi:10.1016/j.annonc.2021.01.003.
[3]. WHO Classification of Tumours Editorial Board. Thoracic Tumours. 5th ed. Lyon: International Agency for Research on Cancer; 2021. WHO Classification of Tumours, Vol. 5.
[4]. Petrella F, Cara A, Cassina EM, et al. Pulmonary Carcinoids: Diagnostic and Therapeutic Approach. Cancers (Basel). 2025;17(17):2748. doi:10.3390/cancers17172748.
[5]. Granberg D, Juhlin CC, Falhammar H, Hedayati E. Lung Carcinoids: A Comprehensive Review for Clinicians. Cancers (Basel). 2023;15(22):5440. doi:10.3390/cancers15225440.

Abstract: Keratin, an intracytoplasmic filamentous protein, constitutes nearly 80% of the total protein content of keratinized stratified squamous epithelium and provides structural integrity to epithelial cells. Alterations in the keratinization process are seen in a wide range of hereditary, premalignant, and malignant oral lesions, making keratin an important diagnostic marker in epithelial pathology. Routine Hematoxylin and Eosin (H&E) staining does not selectively demonstrate keratin, as most eosinophilic structures such as collagen, muscle, and secretions stain similarly, making differentiation difficult........

Keywords: Keratin; Oral squamous cell carcinoma; Special stains; Alcian Blue–Periodic Acid Schiff; Papanicolaou stain; Gram stain; Hematoxylin and Eosin.

[1]. Moll R, Divo M, Langbein L. The human keratins: biology and pathology. Histochem Cell Biol. 2008;129(6):705–33.
[2]. Schweizer J, Winter H. Keratin biosynthesis in normal mouse epithelia and in squamous cell carcinomas. J Biol Chem. 1983;258:13268–72.
[3]. Nagle RB, McDaniel KM, Clark VA, Payne CM. The use of antikeratin antibodies in the diagnosis of human neoplasms. Am J Clin Pathol. 1983;79:458–66.
[4]. Rao RS, Patil S, Majumdar B, Oswal RG. Comparison of special stains for keratin with routine H&E stain. J Int Oral Health. 2015;7(4):1–5.
[5]. Srivastava A, Singh A, Sah K, Raj V, Gupta B. Comparison of modified Kreyberg's, modified Papanicolaou, Ayoub-Shklar and Hematoxylin and Eosin stain to demonstrate keratin in paraffin embedded tissue sections. J Dent Spec. 2017;5:131–47.

Abstract: Background: Dental pulp stem cells (DPSCs) possess significant regenerative potential, and their biological behavior is strongly influenced by the mechanical properties of the extracellular matrix. Among these, substrate stiffness plays a pivotal role in regulating stem cell fate through mechanotransduction pathways. This systematic review evaluated the influence of substrate stiffness on DPSC behavior and its implications for pulpo-dentin regeneration......

Keywords: Dental pulp stem cells; extracellular matrix; mechanobiology; pulpo-dentin regeneration; scaffold design; substrate stiffness

[1]. Gartshore L, Haq T, Djemal S. Endodontic implications of dental trauma: useful tips for primary dental care. Br Dent J. 2025 Apr;238(7):545-550.
[2]. Tabassum S, Khan FR. Failure of endodontic treatment: the usual suspects. Eur J Dent. 2016 Jan-Mar;10(1):144-147.
[3]. Alothman FA, Hakami LS, Alnasser A, AlGhamdi FM, Alamri AA, Almutairii BM. Recent advances in regenerative endodontics: a review of current techniques and future directions. Cureus. 2024 Nov 20;16(11):e74121.
[4]. Yamada Y, Nakamura-Yamada S, Kusano K, Baba S. Clinical potential and current progress of dental pulp stem cells for various systemic diseases in regenerative medicine: a concise review. Int J Mol Sci. 2019 Mar 6;20(5):1132.
[5]. Huang GT, Gronthos S, Shi S. Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine. J Dent Res. 2009 Sep;88(9):792-806.

Abstract: Résumé : La tuberculose pseudo tumorale est une forme rare de la tuberculose, il s´agit d´une pathologie qui simule le cancer bronchopulmonaire par sa présentation clinique et radiologique. Nous rapportons le cas d´un patient âgé de 49 ans, tabagique chronique sevré il y a 1 an consultant pour une dyspnée dans un cadre de fléchissement de l´état général........

[1]. Chaouch N, Saad S, Zarrouk M, Racil H, Cheikh Rouhou S, Nefzi K, et al. Difficulté diagnostique de la tuberculose bronchopulmonaire pseudotumorale. Rev Mal Respir. janv 2011;28(1):9‑13.
[2]. Zidi A, Hantous S, Mestiri I, Ben Miled-Mrad K. Aspects tomodensitométriques de la tuberculose broncho-pulmonaire pseudotumorale. Journal de radiologie. 2006;87(4-1)
[3]. Daoudi M, Herrak L, El Ftouh M, Achachi L. Forme pseudo-tumorale d’une tuberculose broncho-pulmonaire chez un immunocompétent mimant un cancer. Pan Afr Med J. 2019;32.
[4]. Ouarssani A, Atoini F, Reda R, Lhou FA, Rguibi MI. Forme pseudotumorale de la tuberculose pulmonaire et les difficultés diagnostic: à propos d’un cas. Pan Afr Med J. 2013;14.
[5]. Cherian MJ, Dahniya MH, Al-Marzouk NF, Abel A, Bader S. Pulmonary tuberculosis presenting as mass lesions and simulating neoplasms in adults. Australian Radiology 1998;42:303-8

Abstract: Background: Excessive gingival display can compromise smile aesthetics by creating an imbalance between visible tooth structure and gingival tissues. Aesthetic crown lengthening is a periodontal surgical approach used to increase clinical crown exposure and establish a harmonious gingival contour. Precise determination of the desired gingival margin is essential for achieving predictable aesthetic results, particularly in the maxillary anterior region.
Aim: To evaluate.......

Keywords: Aesthetic crown lengthening; Chu aesthetic gauge; excessive gingival display; gummy smile; gingivectomy; clinical crown length; gingival margin; periodontal surgery

[1]. Allen EP. Surgical crown lengthening for function and esthetics. Dent Clin North Am. 1993;37(2):163-179.
[2]. Meghana ISS, Bhat AR, Thomas B, Bhandary R, Shenoy N. Building confident smiles using aesthetic crown lengthening procedures with gingivectomy: a report of two cases. J Health Allied Sci NU. 2023;13:581-586.
[3]. Hempton TJ, Esrason F. Crown lengthening to facilitate restorative treatment in the presence of incomplete passive eruption. J Calif Dent Assoc. 2000;28(4):290-298

Abstract: Background: Periodontal diseases are highly prevalent and largely preventable, yet public awareness remains inadequate. Digital platforms offer a low-cost route for oral health education. This study evaluated the reach and engagement of a digital marketing campaign on periodontal health directed at the population of Jamnagar district, Gujarat, India.
Materials and Methods.......

Key Word: Digital marketing; Google Ads; Instagram; Periodontal health; Health awareness; Social media

[1]. Kassebaum NJ, Bernabé E, Dahiya M, Bhandari B, Murray CJ, Marcenes W. Global burden of severe periodontitis in 1990-2010: a systematic review and meta-regression. J Dent Res. 2014;93(11):1045-1053.
[2]. World Health Organization. Global oral health status report: towards universal health coverage for oral health by 2030. Geneva: World Health Organization; 2022.
[3]. Janakiram C, Mehta A, Venkitachalam R. Prevalence of periodontal disease among adults in India: a systematic review and meta-analysis. J Oral Biol Craniofac Res. 2020;10(4):800-806.
[4]. Tonetti MS, Jepsen S, Jin L, Otomo-Corgel J. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: a call for global action. J Clin Periodontol. 2017;44(5):456-462.
[5]. Preshaw PM, Alba AL, Herrera D, Jepsen S, Konstantinidis A, Makrilakis K, et al. Periodontitis and diabetes: a two-way relationship. Diabetologia. 2012;55(1):21-31.

Abstract: Résumé Le mésothéliome pleural est une tumeur agressive dont le diagnostic exige un prélèvement tissulaire représentatif. La négativité d’une cytologie ou d’une biopsie ne permet toutefois pas d’exclure la maladie lorsque la probabilité clinique et radiologique demeure élevée.
Nous rapportons le cas d’un homme de 62 ans, exposé à l’amiante depuis 30 ans, suivi il y a deux ans pour une pleurésie........

[1]. Sauter JL, Dacic S, Galateau-Salle F, Attanoos RL, Butnor KJ, Churg A, et al. The 2021 WHO Classification of Tumors of the Pleura: Advances Since the 2015 Classification. J Thorac Oncol. 2022;17(5):608-622. doi:10.1016/j.jtho.2021.12.014.
[2]. Kindler HL, Ismaila N, Bazhenova L, Chu Q, Churpek JE, Dagogo-Jack I, et al. Treatment of Pleural Mesothelioma: ASCO Guideline Update. J Clin Oncol. 2025;43(8):1006-1038. doi:10.1200/JCO-24-02425.
[3]. Nowak AK, Chansky K, Rice DC, Pass HI, Kindler HL, Shemanski L, et al. The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma. J Thorac Oncol. 2016;11(12):2089-2099. doi:10.1016/j.jtho.2016.08.147.
[4]. Rice D, Chansky K, Nowak AK, Pass HI, Kindler HL, Shemanski L, et al. The IASLC Mesothelioma Staging Project: Proposals for Revisions of the N Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma. J Thorac Oncol. 2016;11(12):2100-2111. doi:10.1016/j.jtho.2016.09.121.
[5]. Rusch VW, Chansky K, Kindler HL, Nowak AK, Pass HI, Rice DC, et al. The IASLC Mesothelioma Staging Project: Proposals for the M Descriptors and for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Mesothelioma. J Thorac Oncol. 2016;11(12):2112-2119. doi:10.1016/j.jtho.2016.09.124

Abstract: Résumé La tuberculose multifocale peut mimer une affection néoplasique disséminée, en particulier lorsque l’imagerie associe nodules pulmonaires, pleurésie et ascite. Nous rapportons l’observation d’un homme de 45 ans, séronégatif pour le VIH, admis pour une dyspnée stade 2 mMRC, une toux sèche, des douleurs abdominales, une diarrhée, des sueurs nocturnes et une altération de l’état général évoluant depuis trois mois. L’examen clinique a objectivé......

[1]. Chaouch N, Saad S, Zarrouk M, Racil H, Cheikh Rouhou S, Nefzi K, et al. Difficulté diagnostique de la tuberculose bronchopulmonaire pseudotumorale. Rev Mal Respir. janv 2011;28(1):9‑13.
[2]. Zidi A, Hantous S, Mestiri I, Ben Miled-Mrad K. Aspects tomodensitométriques de la tuberculose broncho-pulmonaire pseudotumorale. Journal de radiologie. 2006;87(4-1)
[3]. Daoudi M, Herrak L, El Ftouh M, Achachi L. Forme pseudo-tumorale d’une tuberculose broncho-pulmonaire chez un immunocompétent mimant un cancer. Pan Afr Med J. 2019;32.
[4]. Ouarssani A, Atoini F, Reda R, Lhou FA, Rguibi MI. Forme pseudotumorale de la tuberculose pulmonaire et les difficultés diagnostic: à propos d’un cas. Pan Afr Med J. 2013;14.
[5]. Cherian MJ, Dahniya MH, Al-Marzouk NF, Abel A, Bader S. Pulmonary tuberculosis presenting as mass lesions and simulating neoplasms in adults. Australian Radiology 1998;42:303-8

Abstract: Background: To evaluate and compare triclosan containing toothpaste and non-triclosan containing toothpaste in the management of gingivitis patients. Materials and Methods: 48 participants with gingivitis were divided into two groups with 24 participants each. Each participant received ultrasonic scaling. After ultrasonic scaling, group I was asked to use 0.3% triclosan containing......

Key Word: Triclosan toothpaste, Stanous fluoride, Gingivitis , Dental plaque, Plaque control, Gingival Bleeding

[1]. Bartold PM, Walsh LJ, Narayanan AS. Molecular and cell biology of the gingiva. Periodontology 2000. 2000 Oct 1;24(1).
[2]. Chapple IL, Van der Weijden F, Doerfer C, Herrera D, Shapira L, Polak D, Madianos P, Louropoulou A, Machtei E, Donos N, Greenwell H. Primary prevention of periodontitis: managing gingivitis. Journal of clinical periodontology. 2015 Apr;42:S71-6.
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[4]. Anushree B, Fawaz MA, Narahari R, Shahela T, Syed A. Comparison of antimicrobial efficacy of triclosan-containing, herbal and homeopathy toothpastes-an invitro study. Journal of Clinical and Diagnostic Research: JCDR. 2015 Oct 1;9(10):DC05.
[5]. Smiline GAS, Pandi SK, Hariprasad P, Raguraman R. A preliminary study on the screening of emerging drug resistance among the caries pathogens isolated from carious dentine. Indian J Dent Res. 2012;23(1):26–30.

Abstract: Objective: The aim of the present study was to assess the sociodemographic and clinical characteristics of COPD patients. Methods: A cross sectional study was conducted at the National Institute of Diseases of Chest and Hospital (NIDCH), Mohakhali, Dhaka from September 2022 to August 2023. During the study period 46 samples were collected. Acute exacerbation of COPD patients admitted to NIDCH with met the selection criteria was......

Key Word: D-dimer level, CTPA, pulmonary embolism, COPD, Sociodemographic characteristics

[1]. Agustí, A., Celli, B.R., Criner, G.J., Halpin, D., Anzueto, A., Barnes, P., Bourbeau, J., Han, M.K., Martinez, F.J., Montes de Oca, M. and Mortimer, K., 2023. Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary. American journal of respiratory and critical care medicine, 207(7), pp.819-837.
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Sutradhar, I., Gupta, R.D., Hasan, M., Wazib, A., Sarker, M., 2019. Prevalence and risk factors of chronic obstructive pulmonary disease in Bangladesh: a systematic review. Cureus, 11(1)
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[4]. Flattet, Y., Garin, N., Serratrice, J., Perrier, A., Stirnemann, J. and Carballo, S., 2017. Determining prognosis in acute exacerbation of COPD. International journal of chronic obstructive pulmonary disease, pp.467-475.
[5]. Herer, B. and Chinet, T., 2018. Acute exacerbation of COPD during pulmonary rehabilitation: outcomes and risk prediction. International Journal of Chronic Obstructive Pulmonary Disease, pp.1767-1774

Abstract: Background: Hypertensive emergency is a serious clinical condition characterized by severe elevation of blood pressure with acute target end-organ damage, requiring urgent evaluation and management. Aim: To assess the correlation between hypertensive emergencies and target end-organ damage among different age groups and genders in patients presenting to a tertiary care centre. Materials and Methods: This hospital-based observational study included 67 patients diagnosed with hypertensive emergency.......

[1]. Vinaykumar, S., S. Sanjay, and H. Veena, Hypertensive emergencies in developing countries: clinical profiles and target organ damage. European Journal of Cardiovascular Medicine, 2025. 15: p. 844-851.
[2]. Shin, J.-H., et al., Clinical characteristics and predictors of all-cause mortality in patients with hypertensive urgency at an emergency department. Journal of Clinical Medicine, 2021. 10(19): p. 4314.
[3]. Fragoulis, C., et al., Profile and management of hypertensive urgencies and emergencies in the emergency cardiology department of a tertiary hospital: a 12-month registry. European Journal of Preventive Cardiology, 2022. 29(1): p. 194-201.
[4]. Venugopal, K., A Study of Target Organ Damage in Newly Detected Hypertensives. 2018, Rajiv Gandhi University of Health Sciences (India).
[5]. Fong, R.L. and K.C. Norris, Hypertensive crises, in Acute Emergencies and Critical Care of the Geriatric Patient. 2000, CRC Press. p. 229-242