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Abstract: Background: The simultaneous occurrence of ischemic stroke and spontaneous intracerebral hemorrhage is an exceptionally rare clinical presentation that poses significant diagnostic and therapeutic challenges. Although both conditions...
Keywords: Ischemic stroke; Intracerebral hemorrhage; Pontine hemorrhage; Cerebral small vessel disease; Hypertension; Lacunar infarction; Cerebral microangiopathy
[1].
Kidwell CS, et al. Guidelines for the management of spontaneous intracerebral hemorrhage. Stroke.
[2].
Greenberg SM, et al. 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage. Stroke. 2022.
[3].
Powers WJ, et al. 2021 Guideline for the Prevention of Stroke in Patients With Stroke and TIA. Stroke. 2021.
[4].
Quintas S, et al. Acute ischemic stroke with concomitant intracerebral hemorrhage treated by mechanical thrombectomy. BMJ Case Reports. 2019.
[5].
Pantoni L. Cerebral small vessel disease: from pathogenesis to clinical characteristics. Lancet Neurol. 2010.
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Abstract: Background: Ameloblastoma is a benign odontogenic epithelial tumour characterized by locally aggressive behaviour and a propensity for recurrence. Progressive enlargement may cause substantial mandibular expansion, cortical thinning, tooth displacement, root resorption and facial asymmetry. Its clinical and radiographic features can overlap with other odontogenic lesions, making histopathological examination essential for definitive diagnosis.
Case presentation...
Keywords: Ameloblastoma; mandible; acanthomatous variant; odontogenic tumour; cone-beam computed tomography; case report.
[2].
Milman T, Lee V, LiVolsi V. Ameloblastoma: 25 years of experience at a single institution. Head Neck Pathol. 2016;10(4):513-520.
[3].
Hendra FN, Kalla DS, Van Cann EM, de Vet HCW, Helder MN, Forouzanfar T. Radical vs conservative treatment of intraosseous ameloblastoma: systematic review and meta-analysis. Oral Dis. 2019;25(7):1683-1696.
[4].
Antonoglou GN, Sandor GK. Recurrence rates of intraosseous ameloblastomas of the jaws: a systematic review of conservative versus aggressive treatment approaches and meta-analysis of non-randomized studies. J Craniomaxillofac Surg. 2015;43(1):149-157.
[5].
Almeida R de AC, Andrade ESS, Barbalho JC, Vajgel A, Vasconcelos BC do E. Recurrence rate following treatment for primary multicystic ameloblastoma: systematic review and meta-analysis. Int J Oral Maxillofac Surg. 2016;45(3):359-367.
[6].
Gardner DG. A pathologist's approach to the treatment of ameloblastoma. J Oral Maxillofac Surg. 1984;42(3):161-166..
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Abstract: Background: Guided implant surgery with immediate loading may improve placement accuracy and preserve crestal bone. Aim: To evaluate shaft-guided implant placement accuracy and five-year crestal bone changes using BioHPP abutments. Materials and Methods: This retrospective study included 58 patients receiving 60 implants through a digital workflow. Implant....
Key Word: shaft-guided implant drills, BioHPP abutment, CAD/CAM
[1].
T.-H. Kim, Y.-K. Oh, C.-M. Jeong, E. C. Ko, G. K. Sándor, and Y.-D. Kim, "Soft Tissue Evaluation of an Immediate Esthetic Zone Single Implant with a Stereolithographic Guide Using 3D Reconstruction and a CAD/CAM Customized Titanium Anatomic Abutment," Appl. Sci., vol. 10, no. 5, p. 1678, Mar. 2020, doi: 10.3390/app10051678.
[2].
D. Buser, W. Martin, and U. C. Belser, "Optimizing esthetics for implant restorations in the anterior maxilla: Anatomic and surgical considerations," Int. J. Oral Maxillofac. Implants, vol. 19, no. Suppl., pp. 43–61, 2004.
[3].
N. Donos, A. Horváth, L. A. Mezzomo, D. Dedi, E. Calciolari, and N. Mardas, "The role of immediate provisional restorations on implants with a hydrophilic surface: A randomised, single-blind controlled clinical trial," Clin. Oral Implants Res., vol. 29, no. 1, pp. 55–66, Jan. 2018, doi: 10.1111/clr.13038.
[4].
A. Mahrous, M. M. Radwan, and I. Aboulmagd, "Effect of superstructure material on pink esthetics & marginal bone loss around immediate loading implant: A randomized controlled trial with 1 year follow-up," Egypt. Dent. J., vol. 64, no. 3, pp. 1903–1913, Jul. 2018, doi: 10.21608/edj.2018.78450
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Abstract: Background: Transverse maxillary deficiency with bilateral posterior crossbite frequently coexists with a substantial tooth-size–arch-length discrepancy. Rapid maxillary expansion (RME) reliably corrects the transverse problem, but the arch perimeter it adds may be insufficient to resolve severe crowding. Treatment planning therefore has to separate the two problems.
Materials and Methods,.....
Key Word: Transverse maxillary deficiency, Posterior crossbite, Rapid maxillary expansion (RME), tooth crowding.
[1].
Andrade AS, Gameiro GH, Derossi M, Gavião MBD. Posterior crossbite and functional changes: a systematic review. Angle Orthod. 2009; 79(2):380-386. doi:10.2319/030708-137.1 https://sci-hub.box/10.2319/030708-137.1
[2].
Ugolini A, Agostino P, Silvestrini-Biavati A, Harrison JE, Batista KBSL. Orthodontic treatment for posterior crossbites. Cochrane Database Syst Rev. 2021; 12(12):CD000979. doi: 10.1002/14651858.CD000979.pub3 https://www.researchgate.net/publication/357368939_Orthodontic_treatment_for_posterior_crossbites
[3].
Baccetti T, Franchi L, Cameron CG, McNamara JA Jr. Treatment timing for rapid maxillary expansion. Angle Orthod. 2001; 71(5):343-350. doi:10.1043/0003-3219(2001)071<0343: TTFRME>2.0.CO;2 https://media.dent.umich.edu/labs/mcnamara/files/Treatment%20Timing%20for%20Rapid%20Maxillary%20Expansion.pdf
[4].
Seif-Eldin NF, Elkordy SA, Fayed MS, Elbeialy RA, Eid FH. Transverse skeletal effects of rapid maxillary expansion in pre and post pubertal subjects: a systematic review. Open Access Maced J Med Sci. 2019; 7(3):467-477. doi:10.3889/oamjms.2019.080 https://www.researchgate.net/publication/330995404_Transverse_Skeletal_Effects_of_Rapid_Maxillary_Expansion_in_Pre_and_Post_Pubertal_Subjects_A_Systematic_Review_A_Systematic_Review
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Abstract: Objective: To compare changes in orthodontic knowledge scores after patient-education sessions delivered through five artificial intelligence (AI) platforms: Gemini, Meta AI, ChatGPT, Perplexity, and Grok.
Materials and Methods: This comparative pre–post study included 150 patients aged 14–30 years who were allocated to five groups of 30 participants each. The groups received orthodontic education through Gemini, Meta AI, ChatGPT, Perplexity, or Grok. Knowledge was assessed before and after the educational intervention using the same questionnaire.....
Key Word: artificial intelligence; orthodontics; patient education; health literacy; large language models; knowledge assessment
[1].
Santonocito S, Cicciù M, Ronsivalle V. Evaluation of the impact of AI-based chatbot on orthodontic patient education: a preliminary randomised controlled trial. Clin Oral Investig. 2025;29:278. doi:10.1007/s00784-025-06356-8.
[2].
Salmanpour F, Camcı H, Geniş Ö. Comparative analysis of AI chatbot (ChatGPT-4.0 and Microsoft Copilot) and expert responses to common orthodontic questions: patient and orthodontist evaluations. BMC Oral Health. 2025;25:896. doi:10.1186/s12903-025-06194-w.
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Abstract: Background & Objectives Oral Squamous Cell Carcinoma (OSCC) represents over 90% of all oral malignancies, with a particularly high burden in South Asia. Early detection of OSCC and Oral Potentially Malignant Disorders (OPMDs) is critical for improving.....
Key Word: Oral Squamous Cell Carcinoma, Oral Potentially Malignant Disorders, Brush Cytology, Oral Bethesda System, Buccal Mucosa, Screening
[1].
Montgomery PW, von Haam E. A study of the exfoliative cytology of oral carcinomas. J Dent Res. 1951 Oct;30(5):608-13.
[2].
Halder A, Chakraborty T, Mandal k, Gure PK, Das S, Roychowdhury R. Comparative study of exfoliated oral mucosal cells micronuclei frequency in normal, precancerous and malignant epithelium. Int J Hum Genet 2004; 4:257-60.
[3].
Mohanta A, Mohanty PK, Parida G. Cytomorphometric analysis of keratinized round cells in human oral carcinoma, J Cytol 2015;32:107-12.
[4].
World Health Organization’s (WHO) GLOBOCAN 2022 database, published by the International Agency for Research on Cancer (IARC).
[5].
Kumari P, Debta P, Dixit A. Oral Potentially Malignant Disorders: Etiology, Pathogenesis, and Transformation into Oral Cancer. Front Pharmacol. 2022; 13:825266. doi: 10.3389/ fphar.2022.825266. PMID: 35509742.References
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Abstract: Background: Restoring masticatory function in edentulous patients is crucial for their overall health and quality of life. Prosthetic options like complete dentures (CD), single complete dentures (SCD), and overdentures (OD) vary in their ability to withstand and distribute occlusal forces, influencing patients maximum bite force (MBF). Understanding MBF differences among these prostheses is essential for optimizing treatment outcomes. This topic was selected to address the significant variations in literature regarding MBF capacities of these prostheses, aiming to provide clearer insights for clinical decision-making and improving patient satisfaction.....
Key Word: Maximum bite force; Complete denture; Single complete denture; Implant supported Overdenture; Tooth supported overdenture; Masticatory function
[1]. Trulsson, M., van der Bilt, A., Carlsson, G. E., Gotfredsen, K., Larsson, P., Müller, F., Sessle, B. J., & Svensson, P. (2012). From brain to bridge: masticatory function and dental implants. Journal of oral rehabilitation, 39(11), 858–877. https://doi.org/10.1111/j.1365-2842.2012.02340.x
[2]. Rosa, L.B., Bataglion, C., Siéssere, S., Palinkas, M., Mestriner, W., Freitas, O.D., Rossi, M.D., Oliveira, L.F., & Regalo, S.C. (2012). Bite force and masticatory efficiency in individuals with different oral rehabilitations. Open Journal of Stomatology, 2, 21-26.. https://doi.org/10.4236/OJST.2012.21004
[3]. Manzon, L., Vozza, I., & Poli, O. (2021). Bite Force in Elderly with Full Natural Dentition and Different Rehabilitation Prosthesis. International journal of environmental research and public health, 18(4), 1424. https://doi.org/10.3390/ijerph18041424
[4]. van der Bilt A. (2011). Assessment of mastication with implications for oral rehabilitation: a review. Journal of oral rehabilitation, 38(10), 754–780. https://doi.org/10.1111/j.1365-2842.2010.02197.x.
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Abstract: Background Sepsis and septic shock remain major causes of morbidity and mortality worldwide. Recent evidence suggests that a combination of intravenous vitamin C, hydrocortisone, and thiamine may improve outcomes in critically ill septic patients. Methods A prospective randomized.....
Key Word: Sepsis; Septic Shock; Vitamin C; Thiamine; Hydrocortisone; Critical Care Medicine
[1].
Wilson JX. Evaluation of vitamin C for adjuvant sepsis therapy. Antioxid Redox Signal. 2013.
[2].
Fowler AA, et al. Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis. J Transl Med. 2014.
[3].
Donnino MW, et al. Thiamine deficiency in critically ill patients with sepsis. J Crit Care. 2010.
[4].
Sprung CL, et al. Hydrocortisone therapy for patients with septic shock. N Engl J Med. 2008.
[5].
Marik PE, et al. Hydrocortisone, Vitamin C and Thiamine for the Treatment of Severe Sepsis and Septic Shock. Chest. 2017.
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Abstract: Background: Electronic cigarettes remain the most commonly used tobacco product among U.S. middle and high school students, and a substantial share of adolescents who vape do so frequently, with flavored disposable devices. Meta-analyses comparing adult e-cigarette users with smokers and non-smokers report an intermediate and heterogeneous periodontal profile, and often lower bleeding on probing, which has encouraged the perception that vaping is periodontally benign. This review asks whether the mechanistic evidence supports that perception.....
Key Word: Electronic nicotine delivery systems; Vaping; Adolescent; Oral microbiome; Dysbiosis; Periodontitis; Oxidative stress; Periodontal ligament stem cells; School health; Public health policy
[1]. Jamal A, Park-Lee E, Birdsey J, West A, Cornelius M, Cooper MR, et al. Tobacco product use among middle and high school students — National Youth Tobacco Survey, United States, 2024. MMWR Morb Mortal Wkly Rep. 2024;73(41):917-24. doi:10.15585/mmwr.mm7341a2
[2]. Park-Lee E, Dutra LM, Cowan H, Levine B, Sawdey MD, Cooper M, et al. Tobacco product use among middle and high school students in the United States: National Youth Tobacco Survey, 2025. Nicotine Tob Res. 2026 [Epub ahead of print, 23 Jun 2026]. doi:10.1093/ntr/ntag116
[3]. Thiem DGE, Donkiewicz P, Rejaey R, Wiesmann-Imilowski N, Deschner J, Al-Nawas B, et al. The impact of electronic and conventional cigarettes on periodontal health — a systematic review and meta-analysis. Clin Oral Investig. 2023;27(9):4911-28. doi:10.1007/s00784-023-05162-4
[4]. Pesce P, Menini M, Ugo G, Bagnasco F, Dioguardi M, Troiano G. Evaluation of periodontal indices among non-smokers, tobacco, and e-cigarette smokers: a systematic review and network meta-analysis. Clin Oral Investig. 2022;26(7):4701-14. doi:10.1007/s00784-022-04531-9
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Abstract: Background: Fine-needle cytology (FNAC) is a crucial, low-cost diagnostic tool for breast lesion in resource-limited areas. This study evaluates the diagnostic utility of the International Academy of Cytology (IAC) Yokohama System in peripheral Jharkhand by correlating its standardized categories with histological outcomes. Materials and Methods: A cross-sectional study evaluated 113 patients presenting with palpable breast lumps. Cytology smears were categorized from C1 (Inadequate) to 113 patients Histopathological examination (HPE) correlation was available for 75 cases. Diagnostic metrics were analyzed across three interpretation thresholds (Scenario 1:C3-C5.....
Key Word: FNAC, IAC, Yokohama system, Breast lumps, Atypical, Suspicious
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Siegel, R.L.; Miller, K.D.; Wagle, N.S.; Jemal, A. Cancer statistics, 2023. CA Cancer J. Clin. 2023, 70, 7–30. [CrossRef]
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Journal of Pathology and Translational Medicine 2024; 58: 241-248 https://doi.org/10.4132/jptm.2024.07.14
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Kaur, A., Buragohain, P.D., Talukdar, A. et al. Male Breast Cancer: Clinicopathological Characteristics of the Patients Treated in a Tertiary Care Centre in Northeast India. Indian J Surg 88, 472–479 (2026). https://doi.org/10.1007/s12262-025-04336-6
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Kocjan G. Needle aspiration cytology of the breast: Current perspective on the role in diagnosis and management. Acta Med Croatica. 2008;62(4):391-401..

