Abstract: Pantoprazole is a proton pump inhibitor used in the management of hyper gastric secretions and gastroesophageal reflux during pregnancy. However, its prenatal effects on maternal pregnancy outcomes are not well reported when administered at varying doses and at different gestational periods. A post-test-only experimental study design was adopted in conducting this study. A sample size of 30 female albino rats was used for the study. The 30 albino rats were grouped into two broad study categories of 3 control rats and 27 experimental rats. The 27 experimental rats were subdivided into three study groups of nine rats each according to the doses administered as follows: 9 Low dose rats, 9 medium dose rats, and 9 high dose rats. The 9 rats assemblies were further divided into three subgroups.......
Keywords: Pantoprazole, proton pump inhibitor, fetuses, In –utero effects.
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