Abstract: The in-utero exposure to phenytoin or Phenobarbital during pregnancy in the management of maternal neurological disorders like epilepsy, bipolar diseases, seizures among other has been associated with a wide range of fetal congenital malformation ranging from musculoskeletal, neurological and organ system disorders. However, their comparative teratogenic effects in terms of fetal growth have not been well elucidated hence the basis of this study. Therefore, this study seeks to comparatively evaluate fetal effects when exposed to phenytoin or Phenobarbital in development of fetal skeleton in albino rats. In carrying out the study a total of 57 nulliparous female Albino Rats dams from a pure colony/breed 3rd generation was used. The 57 albino rats were categorized into 54 rat experimental groups and 3 rats control. Further, the 54 experimental were broadly categorized into two major groups of 27.....
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