Abstract: Nine samples of dried exudate Acacia Senegal gums collected, and authenticated by studying their physicochemical properties. 50 g per day of Acacia Senegal gum was administered orally to patients of difference ages suffering from gout, for three months. Blood samples were collected from each patients, and controls on the first day of administering Acacia Senegal gum, and once per month for three months. Uric acid, Urea, Creatinine, and Haemoglobin were measured using standard methods. For males patients of different ages namely M1, M2, M3, M4, M5, M6, M7, and M8, the uric acid levels significantly decreased by 67, 26, 46, 15, 10, 8.0, 43, and 13 % respectively, while for females namely F1, and F2 decreased by 38, and 18% respectively. For above males.....
Key words: Acacia Senegal; Uric acid; Urea; Creatinine; Haemoglobin
[1]. Osman. M. E., Williams, P. A., Menzies, A. R., Phillips, G. O. and Baldwin, T.C. (1993). Carbohydr. Res., 246, 303.
[2]. Bliss, D.Z., Stein, T. P., Schleifer. C. R and Stettle, R.G. (1996). Supplementation with Gum Arabic fiber increases fecal nitrogen excretion and lowers serum urea nitrogen concentration in chronic renal failure patients consuming a low protein diet, Am J Clin. Nutr., 63. 392-398.
[3]. Abdulhakeem, A. A., , Adel, M. M., Ammar, C. A., Othman, A. A., (2002). Protective Effects of Oral Arabic Gum Administration on Gentamicin- Induced Nephrotoxicity in Rats, Pharmacological Research, Vol. 46, No. 5, 445 -451.
[4]. Assimon,S.A., Stein, T.P.(1994). Digestible fiber (gum arabic), nitrogen excretion and urea recycling in rats , Nutrition, 10, 544.
[5]. Younes H, Garleb K, Behr S, Remesy C, Demigne C. (1995). Fermentable fibers or oligosaccharides reduce urinary nitrogen excretion by increasing urea disposal in the rat cecum. J Nutr., 125, 1010-6.