iosr-JDMS   Volume-24 ~ Issue-12 ~ December 2025

Abstract: Objective: To explore the role of genomic profiling in transforming oral cancer care, with a focus on early detection, personalized therapy, and global equity. Design: Narrative review and conceptual framework. Setting: Global oncology landscape, with emphasis on low- and middle-income countries.
Results: Genomic profiling enables molecular stratification of oral squamous cell carcinoma (OSCC), guiding targeted therapies and real-time monitoring. Integration with pan-cancer databases and liquid biopsy technologies enhances.....

Keywords: Precison Genomics, Infections and Diseases, Cancer, Genomic Profile and Oral Medicine

...

Abstract: Introduction: Tuberculosis is one of the leading contagious and infectious disease, causing mortality and morbidity in India caused by Mycobacterium tuberculosis. TB involves many different sites. Tubercular lymphadenitis (TBLN) is one of the most common causes of lymph node enlargement in developing countries. FNAC has a very important role to diagnose TBLN. Aim and Objective.....

Keywords: AFB, Cytomorphology, Necrosis, ZN staining

[1]. Organization, W. H. (2019). Global Tuberculosis Report 2019. Https://Iris.Who.Int/Handle/10665/329368
[2]. Kumar A. Lymph Node Tuberculosis. In: Sharma SK, Mohan A, Editors.Tuberculosis. 2nd Ed. New Delhi: Jaypee Brothers Medical Publishers;2009. P. 397-409.
[3]. WHO (2017). Global Tuberculosis Report 2017. Geneva: WHO Press. Https://Apps.Who.Int/Iris/Bitstream/Handle/10665/259366/9789241565516-Eng.Pdf
[4]. Organization, W. H. (2024). Global Tuberculosis Report 2024. World Health Organization. Https://Www.Who.Int/Teams/Global-Tuberculosis-Programme/Tb-Reports/Global-Tuberculosis-Report-2024.
[5]. Shubha AB, Sapna H, Dinesh RB. Tuberculosis Lymphadenitis Presenting A Diagnostic Dilemma - A Case Report. Int J Dent Clin 2010;2:48-52.

Abstract: Background: Computer-Aided Design and Computer-Aided Manufacturing (CAD-CAM) technologies have transformed restorative and prosthetic dentistry by enhancing precision, efficiency, and esthetics. However, their widespread adoption remains variable, especially in developing regions due to cost and training barriers. This study aimed to assess the awareness, usage patterns, and perceptions of CAD-CAM technology among dental professionals in Andhra Pradesh and Telangana, India.
Materials and.....

Keywords: CAD-CAM, Digital Dentistry, Prosthodontics, Awareness, Dental Technology

[1] Mclaren E. CAD/CAM Dental Technology: A Perspective On Its Evolution And Status. Compendium Of Continuing Education In Dentistry (15488578). 2011 May 1;32(4).
[2] Ritter AV. Chairside CAD/CAM In Dentistry. Journal Of Esthetic & Restorative Dentistry. 2003 Mar 1;15(2).
[3] Aslam K, Nadim R. A Review On Cad Cam In Dentistry. JPDA. 2015 Jul;24(03):112.
[4] Nassani MZ, Ibraheem S, Shamsy E, Darwish M, Faden A, Kujan O. A Survey Of Dentists’ Perception Of Chair-Side CAD/CAM Technology. Inhealthcare 2021 Jan 13 (Vol. 9, No. 1, P. 68). MDPI.
[5] Krastev T, Et Al. Utilisation Of CAD/CAM Technology Among Austrian Dentists. Clin Oral Investig. 2023;27(3):1845–1853.

Abstract: Perennial climber Gloriosasuperba L. is utilized in many parts of Africa and Southeast Asia as an ayurvedic medicinal herb. The plant was classified as endangered because of careless wild collection, despite being widely utilized in medicine for its colchicine content. Although it has a low seed set issue as well, it is now being grown because of industrial need. The herb is used to treat a variety of conditions, including snakebite, gout, arthritis, rheumatism, inflammation, ulcers, bleeding piles, skin conditions, and leprosy.Numerous chemicals, including colchicine.....

Keywords: Colchicine, Gloriosine, Ethanopharmacology

[1]. Abhishek, M., Satish, K.V., Santosh, K.S., Deepika, M., Prasad, G.B.K.S. And Dua, V.K., 2011, Investigation Of Antiinflammatory Properties Of Swertia Chirayta And Gloriosa Superba. Recent Res. Sci. Technol., 3 (3): 40-43.
[2]. Acharya, D., Sancheti, G., Shrivastava, A., And Pawar, S., 2006, Rare Herb Of Patalkot: Gloriosa Superb. Traditional Herbs And Medicines, 10-24.
[3]. Banu, H.R. And Nagarajan, N., 2011, Antibacterial Potential Of Glory Lily, Gloriosa Superb Linn. Int. Res. J. Of Pharm., 2 (3) 139-142.
[4]. Faroogi And Sreeramu, 2001, Cultivation Of Medicinal And Aromatic Crops, Niversities Press (India) Private Limited, Hyderabad, India, 108
[5]. Gupta, L.M., Rana, R.C., Raina, R. And Gupta, M., 2005, Colchicine Contents In Gloriosa Superba L. SKUAST-J., 4: 238-241.

Abstract: Gradenigo syndrome is a rare complication of otitis media characterized by the triad of retro-orbital or facial pain, otorrhea, and sixth cranial nerve palsy, resulting from infection extending into the petrous apex. We report the case of an 80-year-old man who presented with a one-week history of horizontal diplopia, facial pain, and otorrhea. Examination revealed an 18–prism-diopter esotropia with a right abduction deficit consistent with a right CN VI palsy.....

Keywords: Gradenigo syndrome; Petrous apicitis; Abducens nerve palsy; Otitis media; Skull base infection

[1]. Chole RA, Sudhoff HH. Chronic Otitis Media, Mastoiditis, And Petrositis. In: Flint PW, Haughey BH, Lund VJ, Niparko JK, Richardson MA, Robbins KT, Et Al., Editors. Cummings Otolaryngology Head And Neck Surgery. 5th Ed. Philadelphia, PA: Mosby; C2010. Pp. 1963–1978.
[2]. Lee NH, Ban JH, Park CY, Kim CC. A Case Of Petrositis With Abducens Palsy. Korean J Otolaryngol-Head Neck Surg. 2006 Aug;49(8):869–872.
[3]. Lutter, S. A., Kerschner, J. E., & Chusid, M. J. (2005). Gradenigo Syndrome: A Rare But Serious Complication Of Otitis Media. Pediatric Emergency Care, 21(6), 384–386. Https://Doi.Org/10.1097/01.Pec.0000166731.70847.D5
[4]. Talmor, G., Vakil, M., Tseng, C., Svider, P., Ying, M., & Eloy, J. A. (2022). Petrous Apicitis: A Systematic Review And Case Presentation. Otology & Neurotology : Official Publication Of The American Otological Society, American Neurotology Society [And] European Academy Of Otology And Neurotology, 43(7), 753–765. Https://Doi.Org/10.1097/MAO.0000000000003600
[5]. Malic, M., Milicic, B., & Gjuric, M. (2021). Unrecognized Petrous Apicitis As A Cause Of Long- Lasting Headache In A 5-Year-Old Child: Case Report. The Journal Of International Advanced Otology, 17(5), 468–470. Https://Doi.Org/10.5152/Iao.2021.8553

Abstract: Background: The surgical removal of impacted mandibular third molars is one of the most common procedures in oral and maxillofacial surgery. The conventional buccal bone cutting technique and the lingual split technique are two widely used approaches, each with distinct advantages and potential complications. Therefore; the present study aimed to compare the clinical outcomes of two surgical techniques used for the extraction of horizontally impacted.....

Keywords: Lingual split technique; Buccal bone cutting; Impacted mandibular third molar; Postoperative complications; Operative time

[1]. Joshi, M., & Kasat, V. (2011). Variations In Impacted Mandibular Permanent Molars: Report Of Three Rare Cases. Contemporary Clinical Dentistry, 2(2), 124-126. DOI: 10.4103/0976-237X.83079
[2]. Fonseca, R. J., Marciani, R. D., & Turvey, T. A. (2008). Oral And Maxillofacial Surgery. Volume I Anesthesia, Dentoalveolar Surgery, Practice Management.
[3]. Kan, K. W., Liu, J. K., Lo, E. C., Corbet, E. F., & Leung, W. K. (2002). Residual Periodontal Defects Distal To The Mandibular Second Molar 6–36 Months After Impacted Third Molar Extraction: A Retrospective Cross‐Sectional Study Of Young Adults. Journal Of Clinical Periodontology, 29(11), 1004-1011
[4]. Singh, K. I., Sharma, A., Bali, A., Malhotra, A., Patidar, D. C., & Tanwar, K. (2019). Comparison Of Modified Lingual Split Technique And Conventional Buccal Bone Cutting Technique For The Surgical Extraction Of Impacted Mandibular Third Molar. Indian Journal Of Dental Sciences, 11(4), 207-213.
[5]. Aniko-Włodarczyk, M., Jaroń, A., Preuss, O., Grzywacz, A., & Trybek, G. (2021). Evaluation Of The Effect Of Surgical Extraction Of An Impacted Mandibular Third Molar On The Periodontal Status Of The Second Molar—Prospective Study.

Abstract: Introduction: The colour stability of resin-based restorative materials basically depends on the type of resin material used. Different solutions such as medicinal syrups, fruit juices and colas can significantly affect colour stability. Moreover, restorative material discolouration might be attributed to the degree of water sorption and matrix resin hydrophilicity. While restorative materials have been tested in the past, adhesive and new resin-based restorative.....

Keywords: BEAUTIFIL II GIOMER SHOFU INC, Cola, Colorimeter, Colour stability, Discolouration, Fruit juice, Medicine syrup, Wizdent WONDER BULKFILL.

[1]. Falkensammer F, Arnetzl Gv, Wildburger A, Freudenthaler J. Color Stability Of Different Composite Resin Materials. J Prosthet Dent. 2013;109(6):378-83.
[2]. Pratap B, Gupta Rk, Bhardwaj B, Nag M. Resin Based Restorative Dental Materials: Characteristics And Future Perspectives. Jpn Dent Sci Rev. 2019;55(1):126-38.
[3]. Jandt Kd, Sigusch Bw. Future Perspectives Of Resin-Based Dental Materials. Dent Mater. 2009;25(8):1001-6.
[4]. Rusnac Me, Gasparik C, Irimie Ai, Grecu Ag, Mesaros As, Dudea D. Giomers In Dentistry - At The Boundary Between Dental Composites And Glass-Ionomers. Med Pharm Rep. 2019;92(2):123-28.
[5]. Van Ende A, De Munck J, Lise Dp, Van Meerbeek B. Bulk-Fill Composites: A Review Of The Current Literature. J Adhes Dent. 2017;19(2):95-109.

Abstract: Background: Peer-Assisted Learning (PAL) is a widely recognized pedagogical method in health professions education. This study evaluated the effectiveness of a PAL program in a Dental Anatomy course from the students' perspective, assessing its impact on learning experience, outcomes, skill development, and overall satisfaction.
Methods: A cross-sectional survey was administered to a cohort of dental students (N=50) who participated in a PAL program for Dental.....

Keywords: Peer-Assisted Learning, Dental Education, Dental Anatomy, Student Engagement, Collaborative Learning, Curriculum Development

[1]. Henzi, D., Davis, E., Jasinevicius, R., & Hendricson, W. (2007). In The Students' Own Words: What Are The Strengths And Weaknesses Of The Dental School Curriculum? Journal Of Dental Education, 71(5), 632-645.
[2]. Kumar, V., Gadbury-Amyot, C. C., & Kassebaum, D. K. (2010). The Role Of Peer-Assisted Learning In Dental Education. Journal Of Dental Education, 74(9), 1005-1015.
[3]. Topping, K. J. (1996). The Effectiveness Of Peer Tutoring In Further And Higher Education: A Typology And Review Of The Literature. Higher Education, 32(3), 321-345.
[4]. Burgess, A., Mcgregor, D., & Mellis, C. (2014). Medical Students As Peer Tutors: A Systematic Review. BMC Medical Education, 14, 115.
[5]. Ross, M. T., & Cameron, H. S. (2007). Peer Assisted Learning: A Planning And Implementation Framework: AMEE Guide No. 30. Medical Teacher, 29(6), 527-545.

Abstract: Background: Laparoscopic cholecystectomy has become the gold standard for symptomatic gallbladder disease, yet perioperative profiles and early outcomes vary across centres, especially in high‑volume government teaching hospitals. This study was undertaken to evaluate clinical presentation, preoperative work‑up, intraoperative findings and early postoperative outcomes of patients undergoing laparoscopic cholecystectomy at a tertiary care hospital.
Material and.....

Keywords: Laparoscopic cholecystectomy; Gallstones; Perioperative outcomes; Postoperative complications; Clavien–Dindo classification.

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Abstract: Background: Orofacial pain (OFP) remains a diagnostic and therapeutic challenge in general dental practice due to its multifactorial etiology and overlapping clinical features.
Objective: To assess the awareness and practice of managing orofacial pain among dental professionals across different educational and experience levels.
Methods: A descriptive cross-sectional study was conducted from July to September 2025 among dental practitioners, interns....

Keywords: Orofacial Pain, Awareness, Dental Practitioners, Neuropathic Pain, Pain Management

[1]. Renton T, Wilson NH. Understanding And Managing Dental And Orofacial Pain In General Practice. Br J Gen Pract. 2016;66(646):236–7. Doi:10.3399/Bjgp16x684901.
[2]. Labanca M, Gianò M, Franco C, Rezzani R. Orofacial Pain And Dentistry Management: Guidelines For A More Comprehensive Evidence-Based Approach. Diagnostics (Basel). 2023;13(17):2854. Doi:10.3390/Diagnostics13172854.
[3]. Ziegeler C, Brauns G, May A. Characteristics And Natural Disease History Of Persistent Idiopathic Facial Pain, Trigeminal Neuralgia, And Neuropathic Facial Pain. Headache. 2021;61:1441–51. Doi:10.1111/Head.14212.
[4]. May A, Hoffmann J. Facial Pain Beyond Trigeminal Neuralgia. Curr Opin Neurol. 2021;34:373–7.
Doi:10.1097/WCO.0000000000000927.
[5]. Šklebar D, Šklebar I, Cesarik M, Barada A, Maletić A. Neuropathic Orofacial Pain–Diagnostic And Therapeutic Challenges. Period Biol. 2015;117:231–7.

Abstract: Background: Adequate sleep is essential for doctors to maintain cognitive efficiency and patient safety. Occupational stress and prolonged working hours predispose healthcare professionals to sleep disturbances. Objectives: To assess sleep quality and daytime sleepiness and determine associated factors among doctors of Agartala Government Medical College.
Methods: A cross-sectional study was conducted among 103 doctors using the Pittsburgh Sleep Quality Index (PSQI) and Epworth.....

Keywords: Poor sleep quality, Long working hours

[1]. Dey R, Dutta S, Bhandari SS. Sleep Quality And Daytime Sleepiness Among The Clinicians Working In A Tertiary Care Center In Sikkim, India. Indian J Psychol Med. 2020 Mar 9;42(2):141-6.
[2]. Alamri FA, Amer SA, Almubarak A, Alanazi H. Sleep Quality Among Healthcare Providers; In Riyadh, 2019. Int J Med Sci Clin Invent 2019 March; 6(5): 4438-48.
[3]. Tesfaye W, Getu A A , Dagnew B, Lemma A, Yeshaw Y. Poor Sleep Quality And Associated Factors Among Healthcare Professionals At The University Of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia. Front. Psychiatry 2004 May;15:1225518.
[4]. Kotronoulas GC, Papadopoulou CN, Papapetrou A, Patiraki E. Psychometric Evaluation And Feasibility Of The Greek Pittsburgh Sleep Quality Index (GR-PSQI) In Patients With Cancer Receiving Chemotherapy. Support Care Cancer. 2011 Nov;19(11):1831-40.
[5]. Omachi TA. Measures Of Sleep In Rheumatologic Diseases: Epworth Sleepiness Scale (ESS), Functional Outcome Of Sleep Questionnaire (FOSQ), Insomnia Severity Index (ISI), And Pittsburgh Sleep Quality Index (PSQI). Arthritis Care Res (Hoboken). 2011 Nov;63(11):287-96.

Abstract: Background: Biliary atresia (BA) is a common surgical cause of jaundice in infancy, characterized by progressive obliterative cholangiopathy. Cystic biliary atresia (CBA) a variant of BA, with relatively good prognosis. The cyst in CBA can be located anywhere along the atretic biliary tree, treated with excision of atretic biliary tree along with cyst and porto enterostomy.
Clinical Description.....

Keywords: Cystic Biliary Atresia, Portal cyst, Portocysto enterostomy.

[1]. Hartley Jl, Davenport M, Kelly Da. Biliary Atresia. The Lancet. 2009;374(9702):1704-1713. Doi:10.1016/S0140-6736(09)60946-6
[2]. Caponcelli E, Knisely As, Davenport M. Cystic Biliary Atresia: An Etiologic And Prognostic Subgroup. J Pediatr Surg. 2008;43(9):1619-1624. Doi:10.1016/J.Jpedsurg.2007.12.058
[3]. Rahamtalla D, Al Rawahi Y, Jawa Zm, Wali Y. Cystic Biliary Atresia In A Neonate With Antenatally Detected Abdominal Cyst. Bmj Case Rep. 2022;15(2):E246081. Doi:10.1136/Bcr-2021-246081
[4]. Siles P, Aschero A, Gorincour G, Et Al. A Prospective Pilot Study: Can The Biliary Tree Be Visualized In Children Younger Than 3 Months On Magnetic Resonance Cholangiopancreatography? Pediatr Radiol. 2014;44(9):1077-1084. Doi:10.1007/S00247-014-2953-9
[5]. Calinescu Am, Rougemont Al, Mclin Va, Rock Nm, Habre C, Wildhaber Be. A Case Series Of Prenatal Hepatic Hilar Cyst In The Presence Of A Gallbladder - Navigating The Dilemma Between Biliary Atresia And Choledochal Cyst. Bmc Pediatr. 2024;24(1):580. Doi:10.1186/S12887-024-05043-Z

Abstract: Background: Palmoplantar psoriasis (PPP) is a chronic, debilitating variant of psoriasis that affects the palms and soles, accounting for 13–15% of all psoriasis cases. Despite limited body surface area involvement, PPP leads to significant functional impairment due to painful fissuring, scaling, and persistent inflammation. Dermoscopy and histopathology play important roles in differentiating PPP from clinically overlapping conditions. Owing to the poor response to topical therapies and limited clinical trials, systemic agents such as methotrexate and....

Keywords: Palmoplantar psoriasis, Apremilast, Methotrexate

[1]. Venkatesan A, Aravamudhan R, Perumal SK, Et Al. Palmoplantar Psoriasis- Ahead In The Race A Prospective Study From A Tertiary Health Care Centre In South India. J Clin Diagn Res 2015; 9: WC01-3.
[2]. Judge MR, Mclean WHI, Muuro CS. Disorders Of Keratinization. In: Burns T, Breathnach S, Cox N, Griffiths C, Editors. Rook‟S Textbook Of Dermatology. 8th Edition. Wiley – Blackwell Publication. 2010;1: 19.93- 19.117
[3]. Cribier BJ. Psoriasis Under The Microscope. J Eur Acad Dermatol Venereol 2006; 20:3-99.
[4]. Farley E, Masrour S, Mckey J, Menter A. Palmoplantar Psoriasis: A Phenotypical And Clinical Review With Introduction Of A New Quality-Of-Life Assessment Tool. J Am Acad Dermatol 2009; 60: 1024– 1031..

Abstract: Accurate estimation of fetal gestational age is essential for optimal antenatal care. Although multiple biometric indices are routinely used. This study evaluated the usefulness of fetal tibial length (TL) in estimating gestational age using ultrasound. In a prospective analysis of 200 normal singleton pregnancies between 15–40 weeks with reliable menstrual histories, standard biometric parameters—BPD, HC, AC, FL—and TL were measured sonographically.
TL showed a clear...

[1]. Dewhurst CJ, Beazley JM, Campbell S. Assessment Of Fetal Maturity And Dysmaturity. Am J Obstet Gynecol. 1972;113(2):141–9.
[2]. Hadlock FP, Harrist RB, Sharman RS, Deter RL, Park SK. Estimation Of Fetal Weight With The Use Of Head, Body And Femur Measurements,A Prospective Study. Am J Obstet Gynecol. 1985;151(3):333–7
[3]. Hellman LM, Kobayashi M, Fillisti L, Lavenhar M, Cromb E. Growth And Development Of The Human Fetus Prior To The Twentieth Week Of Gestation. Am J Obstet Gynecol. 1969;103(6):789–800.
[4]. Callen PW. Callen’s Ultrasonography In Obstetrics And Gynecology. 6th Ed. Philadelphia, PA: WB Saunders; 2017.
[5]. Chitty LS, Altman DG. Charts Of Fetal Size: Limb Bones. BJOG. 2002;109(8):919-29.

Abstract: Executive Summary Hemodynamic instability affects over one-third of ICU patients with mortality rates of 40-59%. This framework presents a state-of-the-art, standardized algorithm integrating the latest machine learning approaches, validated clinical parameters, and implementation strategies based on 2024-2025 research. Based on my comprehensive research of the latest literature and clinical implementations, I’ll now develop a standardized and improved algorithm....

Keywords: hemodynamic instability, ICU, algorithm, implementation, clinical parameters

[1]. Chiang DH, Et Al. (2025). Development And Validation Of A Dynamic Early Warning System With Time-Varying Machine Learning Models For Predicting Hemodynamic Instability. Critical Care, 29:553. Link
[2]. Zhang Y, Et Al. (2025). Personalized And Real Time Hemodynamic Management In Critical Care Using Dynamic Cohort Ensemble Learning (Dynacel). Nature Digital Medicine. Link
[3]. Sharma A, Et Al. (2024). Role Of Artificial Intelligence In Haemodynamic Monitoring. Indian Journal Of Anaesthesia, 68(3). Link
[4]. Chiang DH, Et Al. (2022). External Validation Of A Machine Learning Model To Predict Hemodynamic Instability In Intensive Care Unit. Critical Care, 26:215. Link
[5]. Rahman A, Et Al. (2021). Early Prediction Of Hemodynamic Interventions In The Intensive Care Unit Using Machine Learning. Critical Care, 25:388. Link.

Abstract: Background: L-Lysine is an essential amino acid, meaning that humans cannot produce it. It has been found to stimulate therapeutic angiogenesis in wound healing. Aim of the study: Given the scarcity of research on the efficacy of topical L-Lysine in superficial surgical site infections, the current study was designed to analyze the efficacy of topical L-Lysine in the treatment of superficial surgical site infections. Methods: Following...

Keywords: L-lysine, essential amino acid, superficial surgical site infection

[1]. Barie PS, Wilson SE. Impact of evolving epidemiology on treatments for complicated skin and skin structure infections: The surgical perspective. J Am Coll Surg. 2015;220(1):105-116.e6.
[2]. Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC Definitions of Nosocomial Surgical Site Infections : A Modification of CDC Definitions of Surgical Wound Infections. Infect Control Hosp Epidemiol. 1992;13(10):606–8.
[3]. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care–associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008;36(5):309–32.. [4].
Anderson DJ. Surgical Site Infections. Infect Dis Clin North Am. 2011;25(1):135–53.
[5]. Segal CG, Waller DK, Tilley B, Piller L, Bilimoria K. An evaluation of differences in risk factors for individual types of surgical site infections after colon surgery. Surg (United States). 2014;156(5):1253–60.

Abstract: Background: Preeclampsia, a pregnancy related complication is a very common occurrence affecting 4.6% of pregnancies worldwide and 1.8-16.7% of pregnancies in developing countries. There are several risk factors for it’s development including MTHFR C677T polymorphism. Hence, we planned to study the prevalence of MTHFR C677T polymorphism in preeclampsia. Methods: A total...

Keywords: pre-eclampsia, MTHFRC677T, PCR-RFLP, mutation, homozygous

[1]. Veerabathiran R, Srinivasan K, Jayaprasad P, Et Al. Association Of MTHFR Gene Polymorphism In Preeclampsia And Recurrent Pregnancy Loss: A Case-Control Study From South India. Hum Gene. 2023;37(7):201199. Doi: 10.3390/Biology13090648.
[2]. Salimi S, Saravani M, Yaghmaei M, Fazlali Z, Mokhtari M, Naghavi A, Farajian-Mashhadi F. The Early-Onset Preeclampsia Is Associated With MTHFR And FVL Polymorphisms. Arch Gynecol Obstet. 2015;291(6):1303-1312. Doi: 10.1007/S00404-014-3561-5.
[3]. Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJH, Den Heijer M, Kluijtmans LAJ, Van Den Heuvel LP, Rozen R. A Candidate Genetic Risk For Vascular Disease: A Common Mutation In Methylenetetrahydrofolate Reductase. Nat Genet. 1995;10(1):111-3. Doi: 10.1038/Ng0595-111.
[4]. Zhang L, Sun L, Wei T. Correlation Between MTHFR Gene Polymorphism And Homocysteine Levels For Prognosis In Patients With Pregnancy-Induced Hypertension. Am J Transl Res. 2021;13(7):8253-61.
[5]. Ahmed SF, Ali MM, Kheiri S, Elzaki SEG, Adam I. Association Of Methylenetetrahydrofolate Reductase C677T And Reduced-F Carrier-1 G80A Gene Polymorphism With Preeclampsia In Sudanese Women. Hypertens Pregnancy. 2020;39(1):77-81. Doi: 10.1080/10641955.2020.1725037.