iosr-JDMS   Volume-18 ~ Issue-6 ~ June-2019

Abstract: Objective: The objective of the study is to document the morbidity and mortality pattern of outborn referral neonates referred to RIMS, Ranchi Materials and Methods: This was a prospective observational study undertaken at a tertiary care teaching government hospital, for 1 year. All outborn referral neonates admitted were included in the study. Relevant maternal and neonatal data were included and analyzed. Results: A total of 1880 outborn referral neonate were admitted during the study in which all neonates were included for analysis with 58.13% male and 41.86% female giving a male to female ratio 1.3:1. Most of them were from rural area.......

Keywords Morbidity, neonatal mortality, outborn neonate, referral neonate

[1]. Lawn JE, Cousens S, Zupan J; Lancet Neonatal Survival Steering Team. 4 million neonatal deaths: When? Where? Why? Lancet 2005;365:891‑900.
[2]. Bang AT, Reddy HM, Bang RA, Deshmukh MD. Why do neonates die in rural Gadchiroli, India? (Part II): Estimating population attributable risks and contribution of multiple morbidities for identifying a strategy to prevent deaths. J Perinatol 2005;25 Suppl 1:S35‑43.
[3]. Liu L, Oza S, Hogan D, Perin J, Rudan I, Lawn JE, et al. Global, regional, and national causes of child mortality in 2000‑13, with projections to inform post‑2015 priorities: An updated systematic analysis. Lancet 2015;385:430‑40.
[4]. Registrar General and Census Commissioner of India. Sample Registration System (SRS) Statistical Report 2015, New Delhi. Available from: www.censusindia.gov.in/vital_statistics/SRS_ report_2015.html. [Last accessed on 2018 Jun 11].
[5]. Sankar MJ, Neogi SB, Sharma J, Chauhan M, Srivastava R, Prabhakar PK, et al. State of newborn health in India. J Perinatol 2016;36:S3‑S8.

Abstract: Leprosy, first described in ancient Indian texts from the sixth century B.C,is a nonfatal, chronic infectious disease caused by Mycobacterium Leprae. M. Leprae is an acid-fast obligate intracellular organism that grows very poorly in culture but can be propagated in the armadillo. It proliferates best at 32° to 34°C, the temperature of the human skin and the core temperature of armadillos1. Clinical manifestations are largely confined to the skin, peripheral nervous system, upper respiratory tract, eyes, and testes2. The mode of transmission of leprosy is unknown, but it is probably inhalation of bacilli, which may be excreted from the nasal passages of a multibacillary............

[1]. Mc Adam AJ, Milner DA, Sharpe AH. Infectious Diseases. In (eds): Kumar V, Abbas AR, Aster JC et al. Robbins and Cotran Pathologic Basis of Disease, 9th edt. Saunders Elsevier, 2014; pp. 377.
[2]. Gelber RH. Leprosy. In (eds): Longo DL, Kasper DL, Jameson JL et al. Harrison's Principles of Internal Medicine. 18th edt. The McGraw-Hill Companies,2012; USA. pp. 1359-60.
[3]. Lucas S. Bacterial Diseases. In (eds): Elder DE, Elenitar R, Johnson Jr et al. Lever's histopathology of the skin. 10th edt. Lippincott Williams and Wilkins, 2008; USA; .pp. 558
[4]. NLEP (2016). Progress report for the year 2015-16 ending on 1st March 2016. Central leprosy division, Directorate general of health services, Government of India, New Delhi.
[5]. WHO, Global strategy for further reducing the leprosy burden and sustaining leprosy control activities.2005; 53.

Abstract: Acute appendicitis is the most common cause of an acute abdomen requiring surgery, with a lifetime risk of developing about 7%. Appendicitis is common in less than 50 years old, with a peak incidence in the second and third decades. Symptoms of appendicitis overlap with a number of other conditions making diagnosis a challenge, particularly at an early stage of presentation. The diagnosis of appendicitis is largely clinical and appendicectomy is the treatment of choice. Delayed diagnosis of appendicitis could lead to complications like perforated appendix, peritonitis, sepsis, increased morbidity and mortality. Right iliac fossa pain can be a presenting complaint of different pathologies that may mimic appendicitis especially in the female population causing diagnostic difficulties.......

Key Words: Acute appendicitis, Alvarado Score, Ultrasound, Appendicectomy

[1]. Ergul E. Importance of family history and genetics for the prediction of acute appendicitis. Internet J surg. 2007;10(2).

[2]. Prystowsky JB, Pugh CM, Nagle AP. Appendicitis. Current problems in surgery. 2005 Oct;42(10):694-742.

[3]. Bundy DG, Byerley JS, Liles EA, Perrin EM, Katznelson J, Rice HE. Does this child have appendicitis?. Jama. 2007 Jul 25;298(4):438-51.

[4]. O'Connell PR. The vermiform appendix. InBailey & Love's Short Practice of Surgery 25th Edition 2008 Jun 27 (pp. 1205-1219). CRC Press.

[5]. Omiyale AO, Adjepong S. Histopathological correlations of appendicectomies: a clinical audit of a single center. Annals of translational medicine. 2015 Jun;3(9).

Abstract: Introduction: Head injuries are frequently associated with ophthalmic manifestations andconsequent morbidity, but many of the ophthalmic findings are often ignored andpresent much later to specialist neuro-ophthalmic clinics. Purpose:To evaluate various ocular manifestations of headinjury, to assess the significance of ocular signs in diagnosis and outcome evaluation of such patient. Methods: A prospective study for a period of 2 years (October 2016 to September 2018) in NRI Medical College and General Hospital, Chinakakani. Results: Total number of cases in the.......

Keywords: Ocular trauma , Road Traffic Accident(RTA

[1]. WHO. Strategies for the Prevention of Blindness in National Programmes. A Primary Health Care Approach. 2nd ed. Geneva, England: WHO Library Cataloguing; 1997.p. 74‑6.
[2]. Steinsapir KD, Goldberg RA. Traumatic optic neuropathy.SurvOphthalmol. 1994;38:487–517.
[3]. Epidemiology of Childhood Ocular Trauma in a Northeastern Colombian Region Arch Ophthalmol. 2003;121(10):1439-1445.
[4]. Sharma B, Gupta R, Anand R, Ingle R. Ocular manifestations of head injury And incidence of post-traumatic ocular motor nerve involvement in cases of Head injury: a clinical review. IntOphthalmol. 2014 Aug;34(4):893-900.
[5]. Kulkarni AR, Aggarwal SP, Kulkarni RR, Deshpande MD, Walimbe PB, Labhsetwar AS. Ocular manifestations of head injury: a clinical study. Eye (Lond). 2005 Dec;19(12):1257-63..

Abstract: Hypertension is perhaps one of the most common problems of patients with end stage renal disease(ESRD). Hypertension is highly prevalent ESRD in patients on maintenance hemodialysis (HD). Intradialytic hypertension (IDH) is one such complication responsible for increased morbidity and mortality in chronic kidney disease (CKD) patients undergoing hemodialysis. In India, there is limited data available in the literature for the incidence of IDH in CKD patients on hemodialysis. In this observational study, we evaluated the incidence of IDH in Indian CKD patients undergoing hemodialysis. We found a higher incidence of IDH (31%) in our study than in........

Key Word: Intradialytic hypertension; chronic kidney disease (CKD); Hemodialysis

[1]. Coresh J, Wei GL, McQuillan G, Brancati FL, Levey AS, Jones C, Klag MJ. Prevalence of high blood pressure and elevated serum creatinine level in the United States: findings from the third National Health and Nutrition Examination Survey (1988-1994). Archives of internal medicine. 2001 May 14;161(9):1207-16.Charra B, Calemard E, Ruffet M, Chazot C, Terrat JC, Vanel T, Laurent G. Survival as an index of adequacy of dialysis. Kidney international. 1992 May 1;41(5):1286-91.

[2]. Levin A, Foley RN. Cardiovascular disease in chronic renal insufficiency. American journal of kidney diseases. 2000 Dec 1;36(6):S24-30.Inrig JK, Patel UD, Gillespie BS.Relationship between interdialytic weight gain and blood pressure among prevalent haemodialysis patients. Am J Kidney Dis. 2007; 50(1): 108-118. doi: 10.1053/j.ajkd.2007.04.020

[3]. Stidley CA, Hunt WC, Tentori F, Schmidt D, Rohrscheib M, Paine S, Bedrick EJ, Meyer KB, Johnson HK, Zager PG. Changing relationship of blood pressure with mortality over time among hemodialysis patients. Journal of the American Society of Nephrology. 2006 Jan 1;17(2):513-20.Mees D. Rise in blood pressure during hemodialysis-ultrafiltration: A "paradoxical" phenomenon? Int J Artif Organs. 1996; 19(10): 569-570.

[4]. Sebastian S, Filmalter C, Harvey J, Chothia MY. Intradialytic hypertension during chronic haemodialysis and subclinical fluid overload assessed by bioimpedance spectroscopy. Clinical kidney journal. 2016 Jun 19;9(4):636-43.Darimireddi SK, Salla SP,

Abstract: Background: Serum phosphorous is a significant risk factor for raised carotid intima media thickness (CIMT) with the conventional risk factors. Kidney dysfunction may also affect the clearance of phosphorus, which could be responsible for the calcification of major arteries. Aim: To correlate serum phosphorus with carotid intima media thickness in chronic kidney disease. Material and Methods: In this prospective observational study 190 cases of Chronic Kidney Disease were studied for carotid intima media thickness (CIMT). CIMT was measured using by B-mode ultrasonography using a 5 MHz transducer.Three measurements taken 0.5, 1, 2 cm below carotid bifurcation of common carotid artery on each......

Key Words: Chronic kidney disease,serum phosphorous, carotid intima media thickness,arteriosclerosis

[1]. Singh AK, Farag YM, Mittal BV, Subramanian KK, Reddy SR, Acharya VN, Almeida AF, Channakeshavamurthy A, Ballal HS, Gaccione P, Issacs R. Epidemiology and risk factors of chronic kidney disease in India–results from the SEEK (Screening and Early Evaluation of Kidney Disease) study. BMC nephrology. 2013 Dec;14(1):114.

[2]. Vadakedath S, Kandi V. Dialysis: a review of the mechanisms underlying complications in the management of chronic renal failure. Cureus. 2017 Aug;9(8).

[3]. Kalantar-Zadeh K, Gutekunst L, Mehrotra R, Kovesdy CP, Bross R, Shinaberger CS, Noori N, Hirschberg R, Benner D, Nissenson AR, Kopple JD. Understanding sources of dietary phosphorus in the treatment of patients with chronic kidney disease. Clinical Journal of the American Society of Nephrology. 2010 Mar 1;5(3):519-30.

[4]. Souberbielle JC, Roth H, Fouque DP. Parathyroid hormone measurement in CKD. Kidney international. 2010 Jan 2;77(2):93-100. [5]. Sharma VK, Dwivedi P, Dubey AK. Correlation of serum phosphate with carotid intimal-medial thickness in chronic kidney disease patients. Indian journal of nephrology. 2014 Jan;24(1):15.

Abstract: Worldwide each year, 1.24 million deathsand 20 to 50 million injuries are caused by road traffic crashes.1 The burden of road traffic injuries (RTIs) is increasingand, unless addressed, is projected to become the fifth-leadingcause of death by the year 2030.2 Motorcycle is the most vulnerable vehicle used in India.3,4 Motorcycle helmet laws are there in India, though implementation is very poor.A cross-sectional observational survey was undertaken in Bidhannagar (Salt Lake), located in Kolkata metropolitan area in North 24 District of West Bengal. Motorcycle helmet use and non-use data was collected by the teams in four locations near traffic light signals and on main streets in.......

Keywords: Helmet, Motorcycle, Pillion Riders

[1]. World Health Organization. Global status report on road safety 2013: supporting a decade of action. Geneva: WHO, 2013.
[2]. World Health Organization. Global status report on road safety: time for action. Geneva: WHO, 2009.
[3]. Wadhwaniya S, Gupta S, Tetali S, Josyula LK, Gururaj G, Hyder AA. The validity of self-reported helmet use among motorcyclists in India. WHO South-East Asia J Public Health 2015; 4(1): 38–44

[4]. Olsen CS, Thomas AM, Singleton M, et al. Motorcycle helmet effectiveness in reducing head, face and brain injuries by state and helmet law. InjEpidemiol. ;3(1):8. doi:10.1186/s40621-016-0072-9
[5]. Mathur AK, Gupta A, Bandhu A. Baseline Study on Pattern of Helmet Use in the State of Rajasthan, India. Journal of Health Management:19(3) 1–18..

Abstract: Objectives: This study aims at measuring the clinical outcomes in Psoriasis patients treated with the drugs Methotrexate and Mycophenolate Mofetil. Methods: This Prospective observational study was carried out in dermatology department RIMS for 6 months. Two way ANOVA was used with the help of graph pad prism to determine the response of two drugs, PASI calculator was used for measuring PASI values, P-value was used for comparisons of clinical outcomes between methotrexate and mycophenolate mofetil. Results: In the present study, a total of 54 subjects met the inclusion criteria among 73 patients. Of these, 50% (n=27) patients were in methotrexate..........

Key Words: Psoriasis; Methotrexate; Mycophenolate mofetil

[1]. S.H. Ibbotson, R.S. Dawe. Davidson's principles and practice of medicine. 22nd edition, an imprint of Elsevier Ltd; 2014; 28: 1286-1287.
[2]. Psoriasis. Diagnosis and treatment; updated: may 12, 2017. Available from: https://www .mayoclinic.org/diseases-conditions/psoriasis/diagnosis treatment/ drc-20355845.
[3]. Menter A, Korman NJ, et al. guidelines of care for the management of psoriasis and psoriatic arthritis: section4. Guidelines of care for the management and treatment of psoriasis with traditional systemic agents. J Am Acad Dermatol. 2009 sep; 61(3):451-85.
[4]. May Anne koda-kimble, et al, Applied therapeutics: The clinical use of drugs, 9th edition: 2009; 40.6-40.7
[5]. Feldman SR, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section4. Guidelines of care for the management and treatment of psoriasis with traditional systemic agents. J Am Acad Dermatol. 2009 sep; 61(3):451-85.

Abstract: Malassezia spp. are lipophilic unipolar yeasts recognized as commensals of skin that may be pathogenic under certain conditions. Different Malassezia species can induce superficial skin infections, and most frequent is pityriasis versicolor (PV), a chronic and recurrent skin disease occurring primarily in hot and humid climates. The purpose of this study was to determine the species prevalence of Malassezia yeasts among clinical cases of Pityriasis versicolor. 96 clinically suspected PV patients were subjected to detailed history, clinical examination and investigations. Skin scrapings were processed by direct microscopy and culture. Isolates were processed.........

Keywords: Malassezia, pityriasis versicolor, lipophilic, tween assimilation

[1]. Gupta AK, Batra R and Dawson T et al. Skin disease associated with Malassezia species. J Am Acad Dermatol 2004; 51:785-98.
[2]. Gupta AK, Kohli Y and Faergemann et al. Epidemiology of the Malassezia yeast associated with Pityriasis Versicolor in ontario, Canada. Med Mycol.2001; 39:199-06.
[3]. Downing DT, Stewart ME, Strauss JS. Changes in sebum secretion and the sebaceous gland. Dermatol Clin 1986; 4: 419-23 [Pubmed]
[4]. Gaitanis G, Magiatis P, Hantschke M, Bassukas ID, Velegraki A. The Malassezia genus in skin and systemic diseases. Clin Microbiol Rev 2012; 25: 106-41. [Pubmed]
[5]. Gemmer CM, DeAngelis YM, Theelen B, Boekhout T, Thomas L. Dawson J. Fast, Non-invasive Method for Molecular Detection and Differentiation of Malassezia Yeast Species on Human Skin and Application of the Method to Dandruff Microbiology. J Clin Microbiol. 2002; 40: 3350–3357.

Abstract: Objective: Iron deficiency is common among women of childbearing age in both the developed and developing countries. Intravenous Ferric carboxy maltose (FCM) is a novel molecule which can be safely administered in a single dose as large as 1000mg in as little as 15 minutes with no significant adverse effects. The aim of the study was to compare the safety and efficacy of Ferric carboxy maltose (FCM) with Iron sucrose(IS) to treat iron deficiency anaemia. Methods: 70 women of iron deficiency anaemia were allocated into two groups. Iron sucrose group - subjects were given I.V. IS in multiple doses,200 mg/day on day,2,4,6, 8 total of 1000 mg. FCM group - subjects were given I.V. FCM 1000 mg single dose. In both..........

[1]. Bernd Froessler,Joshua Collingwood, Nicolette A Hodyl,Gustaaf Dekker. Intravenous ferric carboxymaltose for anaemia in pregnancy. BMC pregnancy and Childbirth 2014; 14(115).
[2]. Erin McLean, Ines Egli and Mary Cogswell. WHO global database on anemia . 2008
[3]. World Health Organization. Reduction of maternal mortality. A joint WHO/UNFPA/UNICEF/World Bank statement. Geneva:WHO;1999
[4]. Bodnar LM, Cogswell ME, RN PH, McDonald T. have we forgotten the significance of postpartum iron deficiency? American Journal of Obstetrics and Gynecology 2005; 195:36-44
[5]. KlaireExarchou, NancyTanahill, andreaanthoney, Atif Khalil and Shahed Ahmed. Efficacy and safety profile of single dose intravenous ferric carboxymaltose in the management of renal anemia a single center experience. Nephrology Dialysis Transplantation May 2013; 28(1):i363-364

Abstract: Rehabilitation of patients with partially edentulous maxillary and mandibular arches entails a very comprehensive diagnosis and treatment planning for the operator. Long term complications and benefit to risk ratio has to be evaluated before selecting a treatment plan. This holds true especially if the remaining teeth under evaluation are bilaterally present maxillary bicuspids and mandibular anterior teeth and bicuspids. To prevent the possibility of an ensuing Combination Syndrome, retaining the maxillary bicuspids becomes critical. Tooth supported overdentures have a long and documented history of preserving the inter-abutment bone loss which is an aftermath of Combination syndrome. Following is hereby a case of maxillary tooth supported overdenture and mandibular cast partial denture.

Keywords: Abutment, Alveolar bone, Combination syndrome, Overdenture, Cast partial denture.

[1]. Atwood DA. Reduction of residual ridges: a major oral disease entity. J Prosthet Dent 1971;26:266-79.
[2]. Tallgren A. The continuing reduction of residual alveolar ridges in complete denture wearers: a mixed-longitudinal study covering 25 years. J Prosthet Dent 1972;27:120-32.
[3]. Bergman B, Carlsson GE. Clinical long-term study of complete denture wearers. J Prosthet Dent 1985;53:56-61.
[4]. Crum RJ, Rooney GE. Alveolar bone loss in overdentures- A five year study. J Prosthet Dent 1978;40:610-613.
[5]. Sennerby L, Carlsson GE, Bergman B, WarfuingeJ. Mandibular bone resorption in patients treated with tissue-integrated prosthesis and in complete-denture wearers. ActaOdontolScand 1988;46:135-140..

Abstract: Le séminome est une pathologie rarechez l'enfant, souvent découverte à un stade précoce devant une masse intrascrotale, exceptionnellement devant une gynécomastie. Son pronostic estgénéralement bon, en particulier dans les tumeurs de stade I. Des taux de guérison peuvent être atteints grâce àde nombreux moyens thérapeutiques: le traitement standard par radiothérapie, la surveillance et la chimiothérapie. Nous rapportons le cas d'un enfant présentant un séminome testiculairedont le mode de révélation était une gynécomastie bilatérale ; qui est rarement décrit dans cette tranche d'âge........

[1]. Faure-Conter C, Rocourt N, Sudour-Bonnange H, Vérité C, Martelli H, Patte C, Frappaz D, OrbachD.Les tumeurs germinales de l'enfant. Bull Cancer 2013 ; 100 : 381-91.doi : 10.1684/bdc.2013.1729.
[2]. Schneider DT, Calaminus G, Koch S, et al. Epidemiologic analysisof 1,442 children and adolescents registered in the German germ celltumor protocols. Pediatr Blood Cancer 2004 ; 42 : 169-75.
[3]. Song H and Huang C: Clinical analysis on children testicular tumor (attached 55 case reports). Chin J Urol 25: 44-46, 2004 (In Chinese).
[4]. Khan O, Protheroe A: Testis Cancer. Postgrad Med J 2007, 83(984):624-32.
[5]. Stevenson SM, Lowrance WT. Epidemiology and diagnosisof testis cancer. UrolClin North Am 2015;42(3):269–275..

Abstract: Low birth weight is an important determinant of infant and childhood mortality and morbidity. In-spite of nutritional transition, low birth weight remains an important public health problem in developing countries like India. With this context, the present study was conducted to find out the risk factors of low birth weight. A hospital based case-control study was undertaken in the post-natal wards of Bankura Sammilani Medical College & Hospital, Bankura from June 2017 to February 2018 . A total 120 cases (low birth weight newborns) and another 120 matching controls (newborns not low birth weight) with a 1: 1 ratio were studied. Interview of the mothers by........

Keywords: Low birth weight, newborn, risk factors, case-control study

[1]. Ryan CA, Ryan F, Keane E, Hegarty H. Trend analysis and socio-economic differentials in infant mortality in the Southern Health Board, Ireland (1988–1997). Ir Med J 2000;93:204-6.
[2]. Chiarotti F, Castignani AM, Puopolo M, et al. Effects of socio-environmental factors on neurocognitive performance in premature or low-birth weight preschoolers. Ann Ist Super Sanita 2001; 37:553-9.
[3]. Singh G, Chouhan R, Sidhu K. Maternal factors foright babies. Medical Journal Armed Forces India.2009; 65:10-12.
[4]. Nagargoje MM, Chaudhary SS ,Deshmukh JS, Mishra SK.A case control study for risk factors of low birth weight in Nagpur city of Maharastra. Indian J Community Med. 2011 ; 22(2):4-7.
[5]. Kohler L, Jakobsson G. Growth and development. In: Children‟s health and well-being in the Nordic countries. London:Mac Keith Press; 1987. p. 75-81..

Abstract: Background: Carcinoma of the stomach has been described as one of the captains of man of death. Modern imaging techniques, especially Computed Tomography remains the most widely used imaging modality for pre-operative staging. CT not only can demonstrate gastric wall and perigastric tissue but also can demonstrate the direct extension of tumor into contiguous organs and presence of distant metastasis. Here we have assessed accuracy of pre-operative radiological staging of gastric carcinoma and its correlation with post-operative findings - a study in a tertiary care hospital of eastern india. Methods: Between MAY 2018 and........

Keywords: Carcinoma Stomach; Spiral Computed Tomography; Pre operative staging

[1]. Gore R. Gastrointestinal cancer. Radiol Clin North Am 1997: 35:295-310.
[2]. Fenogilo-Preiser C. Cameiro F. Correa P, et al. Gastric carcinoma. In: Hamilton S. Aaitonin L. eds. Pathology and Genetics. Tumors of the Digestive System, vol 1 Lyon. France: Lyon Press: 2000:37-52.
[3]. Livingston E. Stomach and duodenum. In: Norton J Bollinger R, Chang A. et al., eds. Surgery. Basic Science and Clinical Evidence. New York: Springer-Verlag 2001:489-515.
[4]. Albert C. Clinical Aspects of Gastric Cancer Gastrointestinal Cancers: Biology, Diagnosis, and
[5]. Therapy. Philadelphia: Lippincot-Raven: 1995:197-216.